Amit Berson, PhD
Amit investigates the molecular mechanisms underlying ALS/FTD with a focus on the contribution of epigenetic mechanisms and their potential use in developing novel therapeutics.
email: amitbe at sas.upenn.edu
Leeanne McGurk, PhD
email: lmcgurk at sas.upenn.edu
China Byrns, MD-PhD candidate in Neuroscience
China studies the role of glia in the pathophysiology of traumatic brain injury, using a fly model to dissect the molecular mechanisms driving inflammation and decline post-injury.
email: china.byrns at uphs.upenn.edu
Chia-Yu Chung, PhD candidate in Genetics & Epigenetics
Chia-Yu investigates the role of transcription factors and complexes in the molecular pathophysiology of ALS/FTD.
email: chiach at pennmedicine.upenn.edu
Lindsey Goodman, PhD candidate in Neuroscience
Lindsey has developed a number of novel gain of function models for C9orf72-associated ALS/FTD. Her continued work uses these fly models and human derived samples to define disease mechanisms.
email: goodmanl at upenn.medicine.edu
Alexandra Perlegos, PhD candidate in Neuroscience
Alexandra focuses on the RNA modification N6-methyladenosine (m6A) and understanding its critical role in cellular stress as well as chronic stress states in the brain, particularly aging and degenerative disease.
email: perlegos at pennmedicine.upenn.edu
Janani Saikumar, PhD candidate in Biology
Janani developed and characterized a novel model of traumatic brain injury in flies and is using it to study perturbations of the cellular stress response and its role in TBI pathophysiology.
email: sjanani at sas.upenn.edu
Ananth Srinivasan, PhD candidate in Biology
Ananth studies the impact of microRNA-34 on healthy brain aging and susceptibility to neurodegenerative disease.
email: ananths at sas.upenn.edu
Olivia Rifai, Research specialist
Olivia originally joined the lab as an undergraduate in Penn’s Vagelos Scholars Program. In her current position, she investigates the role of poly(ADP-ribose) polymerases in TDP-43 degradation and Ataxin-2 toxicity in a fly model.
email: orifai at sas.upenn.edu
Johanna Inamagua, Research assistant
Johanna is a sophomore at Penn. She works with Ananth to study the impact of Polycomb Repressive Complex 2 on brain aging.
email: johannai at sas.upenn.edu
Zhecheng Jin, Research assistant
Jin is a visiting junior at Penn. He works with China characterizing novel molecular processes involved in the response to traumatic brain injury.
email: zhecheng at sas.upenn.edu
Sofiya Patra, Research assistant
Sofiya is a junior at Penn, majoring in Biology with a concentration in Neuroscience. She works with Alex studying the role of the m6A RNA modification in aging and cellular stress.
email: spatra at sas.upenn.edu
Luis Martinez Ramirez, Research assistant
Luis is a senior at Penn, majoring in Biology with a minor in Chemistry. He works with Lindsey and has helped define the PAF1 complex as a modifier of C9orf72-associated ALS/FTD.
email: martluis at sas.upenn.edu
For a complete list of past members of the Bonini lab, see here.