news

Takashi is commended by the ASCB Porter Prize committee for outstanding research.

 

Takashi’s paper on molecular and evolutionary strategies of meiotic cheating by selfish centromeres is available on bioRxiv.

 

Huaiying and Takashi  give talks at the 2018 ASCB annual meeting in San Diego in Minisymposium 10 (Phase Transitions in the Cell) and Minisymposium 11 (Spindle Mechanics and Chromosome Segregation).

 

Runi gives a talk and and Takashi presents a poster at the 2018 Germ Cells meeting at Cold Spring Harbor.

 

Takashi gives a talk and Runi presents a poster at the 2018 Centromere Biology Gordon Research Conference.

 

Takashi receives the 2018 Kaushal Family Award in Genetics, from the Department of Genetics, Perelman School of Medicine, University of Pennsylvania.

 

Takashi’s optogenetics methods chapter is published in Mouse Oocyte Development: Methods and Protocols, edited by Terret and Verlhac.

 

Takashi receives the 2018 Holtzer award from the Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania.

 

Huaiying’s optogenetics methods chapter is published in a Mitosis and Meiosis volume edited by Maiato and Schuh.

 

Huaiying presents her work in Heidelberg at an EMBO / EMBL Symposium: Cellular Mechanisms Driven by Liquid Phase Separation.

 

Our review on cellular and molecular mechanisms of centromere drive is published.

 

Takashi’s paper showing how selfish centromeres exploit spindle asymmetry in meiosis to bias their transmission to the egg is published in Science. The paper is featured in a Perspective and video from Science, Highlight in Nature Reviews Molecular Cell BiologyDispatch in Current Biology, Spotlight in Trends in Cell Biologyreview in Current Opinion in Cell Biologyand in Natural History Magazine.

 

We are presenting our work at the 2017 ASCB annual meeting in Philadelphia:

Huaiying has a talk and a poster on “optogenetic control of nuclear body assembly”. Her talk is Sunday, Dec. 3 at 6:05 pm in Minisymposium 3: Inside the Nucleus: Genome Organization and Gene Expression. The poster is Tuesday, December 5, board B392.

Huaiying has another poster titled “Optogenetic manipulation of individual kinetochores shows that Aurora B kinase promotes microtubule depolymerization rather than detachment”. Sunday, December 3, board B207.

Takashi has a talk and a poster titled “microtubule destabilizing activity of selfish centromeres drives non-Mendelian segregation”. His talk is Sunday, Dec. 3 at 5:50 pm in Minisymposium 6: Regulation of Cell Size, Mitosis and Meiosis. The poster is Monday, December 4, board B242.

Runi has a poster on “mechanisms of quantitative transmission of CENP-A nucleosomes through the germline”. Tuesday, December 5, board B226

 

Lukas’s book chapter on the cell biology of female meiotic drive is published.

 

Takashi’s paper showing how selfish centromeres exploit spindle asymmetry in meiosis to bias their transmission to the egg is available on bioRxiv.

 

Huaiying’s paper showing that we can control motor activity and mitotic checkpoint signaling at kinetochores with light, using new optogenetic tools, is published in Nature Chemical Biology and featured in a News & Views by Figueiredo and Maiato. It is also highlighted in Nature Methods.

 

Runi’s review on centromere inheritance through the germline is published.

 

Aiko’s paper showing that amplified satellite DNA repeats at centromeres act as selfish elements in female meiosis is published in Current Biology.