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Welcome to the Rhoades lab!

We are interested in understanding the underlying principals that govern the functions of intrinsically disordered proteins and why these proteins are so frequently associated with disease.  To do this, we use single-molecule fluorescence and other biophysical techniques to study protein conformations and dynamics, protein-protein interactions, and protein-membrane interactions.

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Currently, the proteins of interest to our group include tau, α-synuclein, islet amyloid polypeptide, and troponin.

Single molecule fluorescence – applied to protein molecules that are either diffusing freely through solution (using confocal microscopy) or those localized to a surface (using total internal reflection microscopy) – is an elegant and powerful approach to studying biological molecules and processes.

Lab News

  • June 2017 – Goodbye to Xiaohan! He is off to England to begin a post-doc in the Babu lab at the Laboratory for Molecular Biology in Cambridge, England. We will miss you, Xiaohan!
  • June 2017 – We welcome new BMB graduate student, Karen Acosta, and congratulate her on receiving a Structural Biology and Molecular Biophysics Training Grant slot!
  • May 2017 – Congratulations to Hope Merens! She is one of the Vagelos Science Challenge Award Winners for 2017-2018!
  • May 2017 – We welcome undergraduate CEMB researcher Richard Potter to the lab!
  • May 2017 – Congratulations to Xiaohan Li on successfully defending his thesis!
  • April 2017 – Sanju passed prelims; Buyan passed candidacy – congratulations to them both!
  • Feb 2017 – Members of the Rhoades lab presented posters (Siobhan Toal, Xiaohan Li, and Melissa Birol) and a talk (Ana Melo) at the Biophysical Society Annual Meeting in New Orleans.
  • January 2017 – Liz became the Associate Editor of the Proteins section of the Biophysical Journal.

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