From the University of Pennsylvania

85) Samsuzzoha Mondal, Karthik Narayan, Samuel Botterbusch, Imania Powers, Jason Zheng, Rui Jin, Tobias Baumgart (2022). Multivalent Interactions between Molecular Components Involved in Clathrin Independent Endocytosis Drive Protein Phase Separation. In Print, Nature Communications. BioRxiv preprint

84) Rui Jin, Rui Cao, Tobias Baumgart (2022). Curvature dependence of BAR protein membrane association and dissociation kinetics. Scientific Reports. DOI

83) Mehdi Molaei, Sreeja Kutty Kandy, Zachary Graber, Tobias Baumgart, Ravi Radhakrishnan, John Crocker (2022). Probing lipid membrane bending mechanics using gold nanorod tracking. DOI

82) Rui Jin, Tobias Baumgart (2021). Asymmetric desorption of lipid oxidation products induces membrane bending. Soft Matter. DOI

81) Rui Jin, Michael Grasso, Mingyang Zhou, Ronen Marmorstein, Tobias Baumgart (2021). Unfolding Mechanisms and Conformational Stability of the Dimeric Endophilin N-BAR Domain. ACS Omega. DOI

80) Robustelli J and Baumgart T (2021). Membrane partitioning and lipid selectivity of the N-terminal amphipathic H0 helices of endophilin isoforms. Biochimica et Biophysica Acta (BBA)-Biomembranes. DOI

79) Botterbusch S, Baumgart T (2021). Interactions between Phase-Separated Liquids and Membrane Surfaces. Applied Sciences. DOI

78) Shukla S and Baumgart T (2020). Enzymatic trans-bilayer lipid transport: mechanisms, efficiencies, slippage, and membrane curvature. Biochimica et Biophysica Acta (BBA) – Biomembranes. DOI

77) Mondal S, Powers, I, Narayan K, Botterbusch S and Baumgart T. (2020). Endophilin recruitment drives membrane curvature generation through coincidence detection of GPCR loop interactions and negative lipid charge. Journal of Biological Chemistry. DOI

76) Shukla S, Jin R, Robustelli J, Zimmerman ZE, & Baumgart T. (2019). PIP2 reshapes membranes through asymmetric desorption. Biophysical journal117(5), 962-974. DOI

75) Wilner SE, Xiao Q, Graber ZT, Sherman SE, Percec V, Baumgart T (2018). Dendrimersomes exhibit lamellar-to-sponge phase transitions. Langmuir, 34(19):5527-34 DOI

74) Shi Z, Graber ZT, Baumgart T, Stone HA, Cohen AE (2018). Cell membranes resist flow. Cell, 175(7):1769-79 DOI

73) Bassereau P, Jin R, Baumgart T, Deserno M, Dimova R, Frolov VA, Bashkirov PV, Grubmüller H, Jahn R, Risselada HJ, Johannes L, et al (2018). The 2018 biomembrane curvature and remodeling roadmap. Journal of Physics D: Applied Physics, 51(34):343001 DOI

72) Mandal K, Aroush DR, Graber ZT, Wu B, Park CY, Fredberg JJ, Guo W, Baumgart T, Janmey PA (2018). Soft Hyaluronic Gels Promote Cell Spreading, Stress Fibers, Focal Adhesion, and Membrane Tension by Phosphoinositide Signaling, not Traction Force. ACS nano DOI

71) Buzzacchera I, Xiao Q, Han H, Rahimi K, Li S, Kostina NY, Toebes BJ, Wilner SE, Möller M, Rodriguez-Emmenegger C, Baumgart T, Wilson DA, Wilson C, Klein ML and Percec V (2018). Screening Libraries of Amphiphilic Janus Dendrimers Based on Natural Phenolic Acids to Discover Monodisperse Unilamellar Dendrimersomes. Biomacromolecules 20(2), pp.712-727 DOI

70) Liu C, Deb S, Ferreira VS, Xu E, Baumgart T (2018). Kinetics of PTEN-mediated PI (3, 4, 5) P3 hydrolysis on solid supported membranes. PloS one, 13(2):e0192667 DOI

69) Jankowska KI, Williamson EK, Roy NH, Blumenthal D, Chandra V, Baumgart T, Burkhardt JK (2018). Integrins modulate TCR signaling by constraining actin flow at the immunological synapse. Frontiers in immunology, 9(25) DOI

68) Xiao Q, Sherman SE, Wilner SE, Zhou X, Dazen C, Baumgart T, Reed EH, Hammer DA, Shinoda W, Klein ML, Percec V (2017). Janus dendrimersomes coassembled from fluorinated, hydrogenated, and hybrid Janus dendrimers as models for cell fusion and fission. PNAS, 114(34):E7045-53 DOI

67) Natesan R, Sreeja KK, Roychoudhuri A, Eckmann DM, Ayyaswamy PS, Baumgart T, Pucadyil T, Patil SV, Weaver VM and Radhakrishnan R (2017). Excess area dependent scaling behavior of nano-sized membrane tethers. Physical biology, 15(2):026002 DOI

66) Graber ZT, Shi Z, and Baumgart T (2017). Cations induce shape remodeling of negatively charged phospholipid membranes. Physical Chemistry Chemical Physics, 19:15285-95 DOI

65) Li N, Sharifi-Mood N, Tu F, Lee D, Radhakrishnan R, Baumgart T*, Stebe KJ* (2016). Curvature-driven migration of colloids on tense lipid bilayers. Langmuir, 33(2):600–610 DOI *Co-corresponding authors

64) Haney CM, Cleveland CL, Wissner RF, Owei L, Robustelli J, Daniels MJ, Canyurt M, Rodriguez P, Ischiropoulos H, Baumgart T, Petersson EJ (2016). Site-Specific Fluorescence Polarization for Studying the Disaggregation of α-Synuclein Fibrils by Small Molecules. Biochemistry, 56(5):683–691 DOI

63) Chen Z, Atefi E and Baumgart T (2016). Membrane Shape Instability Induced by Protein Crowding. Biophysical Journal, 111(9):1823-6 DOI

62) Chen Z, Zhu C, Kuo CJ, Robustelli J and Baumgart T (2016). The N-terminal amphipathic helix of Endophilin does not contribute to its molecular curvature generation capacity. Journal of the American Chemical Society, 138(44):14616-22 DOI

61) Xiao Q, Rubien JD, Wang Z, Reed EH, Hammer DA, Sahoo D, Heiney PA, Yadavalli SS, Goulian M, Wilner SE, Baumgart T, Vinogradov SA, Klein ML and Percec V (2016). Self-Sorting and Coassembly of Fluorinated, Hydrogenated, and Hybrid Janus Dendrimers into Dendrimersomes. Journal of the American Chemical Society, 138(38):12655-63 DOI

60) Luo Q, Shi Z, Zhang Y, Chen XJ, Han SY, Baumgart T, Chenoweth DM, Park SJ (2016). DNA Island Formation on Binary Block Copolymer Vesicles. Journal of the American Chemical Society, 138(32):10157-62 DOI

59) Tourdot RW, Ramakrishnan N, Baumgart T, Rahhakrishnan R (2015). Application of a free-energy-landscape approach to study tension-dependent bilayer tubulation mediated by curvature-inducing proteins. PHYSICAL REVIEW E, 92, 042715 DOI

58) Chen Z, Shi Z, Baumgart T (2015). Regulation of membrane shape transitions induced by I-BAR domains. Biophysical Journal, 109(2):298-307 DOI

57) Shi Z, Sachs JN, Rhoades E, and Baumgart T. (2015). Biophysics of α-synuclein induced membrane remodelling. Physical Chemistry Chemical Physics DOI

56) Shi Z and Baumgart T(2015). Membrane tension and peripheral protein density mediate membrane shape transitions. Nature Communications, Vol.6, Article No.5974 DOI Penn News

55) Knorr RL, Nakatogawa H, Ohsumi Y, Lipowsky R, Baumgart T, Dimova T (2014). Membrane morphology is actively transformed by covalent binding of the protein Atg8 to PE-lipids. PLoS ONE, 9 (12), e115357 DOI

54) Wu T,and Baumgart T. (2014). BIN1 Membrane Curvature Sensing and Generation Show Autoinhibition Regulated by Downstream Ligands and PI(4,5)P2. Biochemistry, 53 (46), pp 7297–7309 DOI

53) Shen H, Giordano F, Wu Y, Chan J, Zhu C, Milosevic I, Wu X, Yao K, Chen B, Baumgart T, Sieburth D, De Camilli P.(2014). Coupling between endocytosis and sphingosine kinase 1 recruitment. Nature Cell Biology, 16(7):652-62 DOI

52) Shi Z, and Baumgart T. (2014). Dynamics and instabilities of lipid bilayer membrane shapes. Advances in Colloid and Interface Science, 208, 76–88 DOI

51) Chen Z, Chang K, Capraro BR, Zhu C , Hsu CJ, and Baumgart T. (2014). Intradimer / intermolecular interactions suggest auto-inhibition mechanism in endophilin A1. Journal of the American Chemical Society, 136 (12), 4557–4564 DOI

50) Wu T, Shi Z, Baumgart T. (2014) Mutations in BIN1 associated with Central Nuclear Myopathy disrupt membrane remodeling by affecting protein density and oligomerization. PLoS ONE, 9(4): e93060 DOI

49) Cavallaro M, Gharbi MA, Beller DA, Copar S, Shi Z, Baumgart T, Yang S, Kamien RD, Stebe KJ. (2013). Exploiting imperfections: Assembling surface colloids via bulk topological defects. PNAS, 110(47)18804–18808 DOI

48) Zhao Y, Liu J, Yang, C, Capraro BR, Baumgart T, Bradley RP, Ramakrishnan N, Svitkina T and Guo W. (2013). Exo70 generates negative membrane curvature for morphogenesis and direction cell migration. Developmental Cell, 26 (3) 266 DOI

47) Liao Z, Hsieh W, Baumgart T*, Dmochowski IJ*. (2013). Measuring Interactions between Polydimethylsiloxane and Serum Proteins at the Air−Water Interface. Langmuir, 29 (30), 9420. *Co-corresponding authors DOI

46) Cavallaro M, Gharbi MA, Beller DA, Copar S, Shi Z, Kamien RD, Yang S, Baumgart T, Stebe KJ. (2013). Ring around the colloid. Soft Matter, 9 (38), 9099 DOI

45) Capraro B, Shi Z, Wu T, Chen Z, Dunn J, Rhoades E, Baumgart T. (2013). Dimerization and membrane binding kinetics of endophilin N-BAR. Journal of Biological Chemistry, 288 (18), 12533-12543 DOI

44) Spinler K, Tian A, Christian DA, Pantano DA, Baumgart T*, Discher D*.(2013). Dynamic Domains in Polymersomes: Mixtures of Polyanionic and Neutral Diblocks Respond More Rapidly to Changes in Calcium than to pH. Langmuir, 29 (24), 7499. *Co-corresponding authors DOI

43) May RM, Okumura M, Hsu C, Bassiri H, Yang E, Rak G, Mace EM, Philip NH, Zhang W, Baumgart T, Orange JS, Nichols KE, Kambayashi T. (2012). Murine natural killer immunoreceptors use distinct proximal signaling complexes to direct cell function. Blood, 12, 474361 DOI

42) Chinnapen DJF, Hsieh W, Welscher YM, Saslowsky DE, Kaoutzani L, Brandsma E, D’Auria L, Park H, Wangner JS, Drake KR, Kang M, Benjamin T, Ullman MD, Costello CE, Kenworthy AK, Baumgart T, Massol RH, Lencer WI (2012). Lipid Sorting by Ceramide Structure from Plasma Membrane to ER for the Cholera Toxin Receptor Ganglioside GM1. Developmental Cell, 23 (3), 573-586 DOI

41) Hsieh WT, Hsu CJ, Capraro B, Wu T, Chen CM, Yang S, Baumgart T (2012). Curvature Sorting of Protein Domains on Solid-Supported Wavy Membranes. Langmuir, 28 (35), 12838–12843 DOI

40) Sezgin E, Kaiser HJ, Baumgart T, Schwille P, Simons K, Levental I (2012). Elucidating membrane structure and protein behavior using giant plasma membrane vesicles. Nature Protocols, 7, 1042-1051 DOI

39) Singh P, Paritosh M, Baumgart T, Das S (2012). Curvature sorting of proteins on a cylindrical lipid membrane tether connected to a lipid reservoir. Physical Review E, 85 (5), 051906 DOI

38) Zhu C, Das SL, Baumgart T (2012). Nonlinear sorting, curvature generation, and crowding of Endophilin N-BAR on tubular membranes. Biophysical Journal, 102 (8), 1837-1845 DOI – offered free as a Featured Article

37) Hsu CJ, Hsieh WT, Waldman A, Clarke F, Huseby ES, et al. (2012). Ligand Mobility Modulates Immunological Synapse Formation and T Cell Activation. PLoS ONE 7(2): e32398 DOI

36)Hsu CJ, Baumgart T (2011). “Spatial Association of Signaling Proteins and F-actin Effects on Cluster Assembly Analyzed via Photoactivation Localization Microscopy in T Cells”, PLoS ONE, 6 (8): e23586 DOI

35) Baumgart T, Capraro BC, Zhu C, Das SL (2011). “Thermodynamics and mechanics of membrane curvature generation and sensing by proteins and lipids”, Annual Reviews in Physical Chemistry, 62, 483-506 DOI

34) Heinrich MC, Capraro BR, Tian A, Isas JM, Langen R, Baumgart T (2010). “Quantifying Membrane Curvature Generation of Drosophila Amphiphysin N-BAR Domains”, Journal of Physical Chemistry Letters, 1 (23), 3401 DOI

33) Heinrich M, Tian A, Esposito C, Baumgart T. (2010). Dynamic sorting of lipids and proteins by membrane tubes with a moving phase boundary. Proceedings of the National Academy of the Sciences of the United States of America, 107 (16), 7208-7213 DOI

32) Camley B, Esposito C, Baumgart T, Brown FLH (2010). Lipid bilayer domain fluctuations as a probe of membrane viscosity. Biophysical Journal, 99 (6), L44-L46 DOI

31) Kambayashi T, Okumura M, Baker RG, Hsu CJ, Baumgart T, Zhang W, Koretzky GA (2010). “Independent and cooperative roles of adaptor molecules in proximal signaling during FceRI-mediated mast cell activation”, Molecular and Cellular Biology, 30 (17), 4188 – 4196 DOI

30) (Invited) Johnson S, Stinson B, Go M, Reminick J, Carmona M, Fang X, Baumgart T (2010). Temperature dependent phase behavior and protein partitioning in giant plasma membrane vesicles. Biochimica et Biophysica Acta – Biomembranes, 1798 (7), 1427-1435 DOI

29) Capraro BR, Yoon Y, Cho W, Baumgart T (2010). Curvature sensing by the epsin N-terminal homology (ENTH) domain measured on cylindrical lipid membrane tethers. Journal of the American Chemical Society, 132 (4), 1200-1201 DOI

28) Levental I, Byfield FJ, Choudhourie P, Madara J, Gai F, Baumgart T, Janmey PA (2009). Cholesterol-dependent phase separation in cell-derived giant plasma membrane vesicles. Biochemical Journal, 424 (2), 163-167 DOI

27) Baker RG, Hsu CJ, Lee D, Jordan MS, Maltzman JS, Hammer DA, Baumgar T, Koretzky GA (2009). The adapter protein SLP-76 mediates “outside-in” integrin signaling and function in T cells. Molecular and Cellular Biology, 29 (20), 5578-5589 DOI

26) Christian D, Tian A, Ellenbroek W, Levental I, Rajagopal K, Janmey P, Liu A, Baumgart T, Discher D (2009). Spotted vesicles, striped micelles and Janus assemblies induced by ligand binding. Nature Materials, 8, 843-849 DOI

25) Oh H, Mohler III ER, Tian A, Baumgart T, & Diamond SL (2009). Membrane cholesterol is a biomechanical regulator of neutrophil adhesion. Arteriosclerosis, Thrombosis, and Vascular Biology, 29, 1290-1297 DOI

24) Tian A, Capraro BR, Esposito C, & Baumgart T (2009). Bending stiffness depends on curvature of ternary lipid mixture tubular membranes. Biophysical Journal, 97 (6), 1636-1646 DOI

23) Das SL, Jenkins JT, & Baumgart T (2009). Neck geometry and shape transitions in vesicles with co-existing fluid phases: Role of Gaussian curvature stiffness versus spontaneous curvature. Europhysics Letters, 86, 48003-48008 DOI

22) Tian A & Baumgart T (2009). Sorting of lipids and proteins in membrane curvature gradients. Biophysical Journal, 96(7), 2676-2688 DOI – offered free as a Featured Article

21) Das SL, Tian A, & Baumgart T (2008). Mechanical stability of micropipette aspirated giant vesicles with fluid phase coexistence. Journal of Physical Chemistry, 112 (37), 11625-11630 DOI

20) Heinrich MC, Levental I, Gelman H, Janmey PA, & Baumgart, T (2008). Critical exponents for line tension and dipole density difference from lipid monolayer domain boundary fluctuations. Journal of Physical Chemistry,112 (27), 8063-8068 DOI

19) Esposito C, Tian A, Melamed S, Johnson C, Tee SY, & Baumgart, T (2007). Flicker spectroscopy of thermal lipid bilayer domain boundary fluctuations. Biophysical Journal, 93 (3), 3169-3181 DOI

18) Hess S, Gudheti M, Mlodzianoski M, & Baumgart T (2007). Shape analysis of giant vesicles with fluid phase coexistence by laser scanning microscopy to determine curvature, bending elasticity and line tension. Methods in Molecular Biology, 400, 367-387 DOI

17) Tian A, Johnson C, Wang W, & Baumgart T (2007). Line tension at fluid membrane domain boundaries measured by micropipette aspiration. Physical Review Letters, 98 (20), 208102 DOI

From Cornell University:

16) Wu M, Baumgart T, Hammond S, Holowka D, Baird B (2007). Differential targeting of secretory lysosomes and recycling endosomes in mast cells revealed by patterned antigen. Journal of Cell Science, 120, 3147-3154 DOI

15) Baumgart T, Hunt G, Farkas E, Webb WW,  Feigenson F (2007). Fluorescence probe partitioning between Lo / Ld phases in lipid membranes. Biochimica et Biophysica Acta, 1768 (9), 2182-2194 DOI

14) Baumgart T, Hammond A, Sengupta P, Hess S, Holowka D, Baird B,  Webb WW (2007). Large-scale fluid/fluid phase separation of proteins and lipids in giant plasma membrane vesicles. Proceedings of the National Academy of Sciences of the United States of America,104 (9), 3165-3170 DOI

13) Baumgart T, Das SL, Webb WW, & Jenkins JT (2005). Membrane elasticity in giant vesicles with fluid phase coexistence. Biophysical Journal, 89 (2), 1067-1080 DOI

12) Hammond AT, Heberle FA, Baumgart T, Holowka D, Baird B, & Feigenson GW (2005). Crosslinking a lipid raft component triggers liquid ordered-liquid disordered phase separation in model plasma membranes. Proceedings of the National Academy of Sciences of the United States of America, 102 (18), 6320-6325 DOI

11) Korlach, J, Baumgart, T, Feigenson, GW, Webb, WW (2005). Detection of motional heterogeneities in lipid bilayer membranes by dual probe fluorescence correlation spectroscopy. Biochimica et Biophysica Acta, 1668 (2), 158-163 DOI

10) Baumgart T, Hess ST, Webb WW, (2003). Imaging coexisting fluid domains in biomembrane models coupling curvature and line tension. Nature, 425, 821-824 DOI

From Max Planck Institute for Polymer Research, Germany:

9) Baumgart T, Kreiter M, Lauer H, Naumann R, Jung G, Jonczyk A, Offenhausser A, & Knoll W (2003). Fusion of small unilamellar vesicles onto laterally mixed self-assembled monolayers of thiolipopeptides. Journal of Colloid and Interface Science, 258 (2), 298-309 DOI

8) Baumgart T, Offenhausser A (2003). Polysaccharide-supported planar bilayer lipid model membranes. Langmuir, 19, 1730-1737 DOI

7) Naumann R, Baumgart T, Graber P, Jonczyk A, Offenhausser A, & Knoll W (2002). Proton transport through a peptide-tethered bilayer lipid membrane by the H+-ATP Synthase from chloroplasts measured by impedance spectroscopy. Biosensors & Bioelectronics, 17 (1-2), 25-34 DOI

6) Morigaki K, Baumgart T, Jonas U, Offenhausser A, & Knoll W (2002). Photopolymerization of diacetylene lipid bilayers and its application to the construction of micropatterned biomimetic membranes. Langmuir, 18 (10), 4082-4089 DOI

5) Bolze J, Takahasi M, Mizuki J, Baumgart T, Knoll W (2002). X-ray reflectivity and diffraction studies on lipid and lipopolymer Langmuir-Blodgett films under controlled humidity. Journal of the American Chemical Society, 124 (32), 9412-9421 DOI

4) Baumgart T, Offenhausser A (2002). Spreading of lipid monolayers on hydrophilic substrates at increased relative humidities. Langmuir, 18 (15), 5899-5908 DOI

3) Baumgart T, Offenhauser A (2002). Lateral diffusion in substrate-supported lipid monolayers as a function of ambient relative humidity. Biophysical Journal, 83 (3), 1489-1500 DOI

2) Morigaki K, Baumgart T, Offenhausser A, Knoll W (2001). Patterning solid-spported lipid bilayer membranes by lithographic polymerization of a diacetylene lipid. Angewandte Chemie-International Edition, 40 (1), 172-174 DOI

From University of Clausthal, Germany:

1)Baumgart T, Cramer S, Jahr T, Veniaminov A, Adams J, Fuhrmann J, Jeschke G, Wiesner U, Spiess HW, Bartsch E, Sillescu H (2000). Film-forming colloidal dispersions studied by tracer methods. Macromolecular Symposia, 151, 451-457. DOI