other publications:   reviews   methods

primary research papers

Lampson lab members in bold

Das A, Boese KG, Tachibana K, Baek SH, Lampson MA*, Black BE*. 2023. Centromere-specifying nucleosomes persist in aging mouse oocytes in the absence of nascent assembly. *Shared corresponding authors. pdf

Dudka D, Akins RB, Lampson MA. 2023. FREEDA: an automated computational pipeline guides experimental testing of protein innovation. Journal of Cell Biology. pdf

Das A, Iwata-Otsubo A, Destouni A, Dawicki-McKenna JM, Boese KG, Black BE, Lampson MA. 2022. Epigenetic, genetic and maternal effects enable stable centromere inheritance. Nature Cell Biology. pdf

Kumon T, Ma J, Stefanik D, Nordgren EC, Akins RB, Kim J, Levine M, Lampson MA. 2021. Centromere drive and suppression by parallel pathways for recruiting microtubule destabilizers. Cell. pdf and see Preview by Nikalayevich and Verlhac.

Maier NK¹, , Ma J¹, Lampson MA*, Cheeseman IM*. 2021. Separase cleaves the kinetochore protein Meikin at the meiosis I/II transition. Developmental Cell. ¹Equal contribution. *Shared corresponding authors. pdf

Zhang H, Zhao R, Tones J, Liu M, Dilley R, Chenoweth DM, Greenberg RA, Lampson MA. 2020. Nuclear body phase separation drives telomere clustering in ALT cancer cells. Molecular Biology of the Cell. pdf.

Akera T, Trimm E, Lampson MA. 2019. Molecular strategies of meiotic cheating by selfish centromeres. Cell 178:1-13. pdf and see Dispatch by Schroeder and Malik in Current Biology.

Aonbangkhen A, Zhang H, Wu DZ, Lampson MA*, Chenoweth DM*. 2018. Reversible Control of Protein Localization in Living Cells using a Photocaged-Photocleavable Chemical Dimerizer. Journal of the American Chemical Society 140(38):11926-11930. *Shared corresponding authors. pdf

Akera T, Chmátal L, Trimm E, Yang K, Aonbangkhen C, Chenoweth DM, Janke C, Schultz RM, Lampson MA. 2017. Spindle asymmetry drives non-Mendelian chromosome segregation. Science 358(6363):668-672. pdf and see Perspective by McNally and video from Science, Highlight in Nature Reviews Molecular Cell Biology, Dispatch by Kim and Desai in Current Biology, Spotlight by Laloraya in Trends in Cell Biology, review by Kursel and Malik in Current Opinion in Cell Biology.

Iwata-Otsubo A, Dawicki-McKenna JM, Akera T, Falk SJ, Chmátal L, Yang K, Sullivan BA, Schultz RM, Lampson MA*, Black BE*. 2017. Amplified satellite repeats act as selfish elements in female meiosis. Current Biology 27(15):2365-2373. *Shared corresponding authors. pdf and see Dispatch by Kim and Desai in Current Biology and review by Kursel and Malik in Current Opinion in Cell Biology.

Zhang H, Aonbangkhen C, Tarasovetc E, Ballister ER, Chenoweth DM, Lampson MA. 2017. Optogenetic control of kinetochore function. Nature Chemical Biology 3(10):1096-1101. pdf and see News & Views by Figueiredo and Maiato and Highlight in Nature Methods.

Smoak EM, Stein P, Schultz RM, Lampson MA*, Black BE*. 2016. Long-term retention of CENP-A nucleosomes in mammalian oocytes underpins transgenerational inheritance of centromere identity. Current Biology 26(8):1110-6. *Shared corresponding authors. pdf and see Dispatch by Toth and Jessberger.

Zaytsev AV†, Segura-Peña D†, Godzi M, Calderon A, Ballister ER, Stamatov R, Mayo AM, Peterson L, Black BE, Ataullakhanov FI*, Lampson MA*, Grishchuk EL*. 2016. Bistability of a coupled Aurora B kinase-phosphatase system in cell division. eLife pii: e10644. †Equal contribution. *Shared corresponding authors. pdf

Chmátal L, Yang K, Schultz RM, Lampson MA. 2015. Spatial regulation of kinetochore microtubule attachments by destabilization at spindle poles in meiosis I. Current Biology 25(14):1835-41. pdf and see Dispatch by Monda and Cheeseman.

Ballister ER, Ayloo S, Chenoweth DM, Lampson MA*, Holzbaur EL*. 2015. Optogenetic control of organelle transport using a photocaged chemical inducer of dimerization. Current Biology 25(10):R407-8. *Shared corresponding authors. pdf

Zhang M, Kothari P, Lampson MA. 2015. Spindle assembly checkpoint acquisition at the mid-blastula transition. PLoS One 10(3):e0119285. pdf

Chmátal L, Gabrial SI, Mitsainas GP, Martínez-Vargas J, Ventura J, Searle JB, Schultz RM, Lampson MA. 2014. Centromere strength provides the cell biological basis for meiotic drive and karyotype evolution in mice. Current Biology 24(19):2295-300. pdf and see Dispatch by Ross and Malik.

Ballister ER, Aonbangkhen C, Mayo AM, Lampson MA*, Chenoweth DM*. 2014. Localized light-induced protein dimerization in living cells using a photocaged dimerizer. Nature Communications 5:5475. *Shared corresponding authors. pdf

Ballister ER, Riegman M, Lampson MA. 2014. Recruitment of Mad1 to metaphase kinetochores is sufficient to reactivate the mitotic checkpoint. Journal of Cell Biology 204(6):901-8. pdf

Zhang M, Kothari P, Mullins MC, Lampson MA. 2014. Regulation of zygotic genome activation and DNA damage checkpoint acquisition at the mid-blastula transition. Cell Cycle 13(24):3828-38. pdf

Davydenko O, Schultz RM, Lampson MA. 2013. Increased CDK1 activity determines the timing of kinetochore-microtubule attachments in meiosis I. Journal of Cell Biology 202(2):221-9. pdf

Liu D, Davydenko O, Lampson MA. 2012. Polo-like kinase-1 regulates kinetochore-microtubule dynamics and spindle checkpoint silencing. Journal of Cell Biology 198(4):491-9. pdf and see Comment by Cane and Maresca.

Schindler K†, Davydenko O†, Fram B, Lampson MA*, Schultz RM*. 2012. Maternally-recruited Aurora C kinase is more stable than Aurora B to support mouse oocyte maturation and early development. Proceedings of the National Academy of Sciences 109(33):E2215-22 (Cover). †Equal contribution. *Shared corresponding authors. pdf

Chiang T, Schultz RM, Lampson MA. 2011. Age-dependent susceptibility of chromosome cohesion to premature separase activation in mouse oocytes. Biology of Reproduction 85(6):1279-83. pdf

Wang E, Ballister ER, Lampson MA. 2011. Aurora B dynamics at centromeres creates a diffusion-based phosphorylation gradient. Journal of Cell Biology 194(4):539-549 (Cover). pdf

Salimian KJ, Ballister ER, Smoak EM, Wood S, Panchenko T, Lampson MA*, Black BE*. 2011. Feedback Control in Sensing Chromosome Biorientation by the Aurora B Kinase. Current Biology 21(13):1158-65.  *Shared corresponding authors. pdf

Chiang T, Duncan FE, Schindler K, Schultz RM, Lampson MA. 2010. Evidence that weakened centromere cohesion is a leading cause of age-related aneuploidy in oocytes. Current Biology 20(17):1522-8. pdf and see Time.com feature and Dispatch by Hunt and Hassold.

Liu D, Vleugel M, Backer CB, Hori T, Fukagawa T, Cheeseman IM, Lampson MA. 2010. Regulated targeting of protein phosphatase 1 to the outer kinetochore by KNL1 opposes Aurora B kinase. Journal of Cell Biology 188(6):809-20 (Cover). pdf

Liu D, Vader G, Vromans MJ, Lampson MA*, Lens SM. 2009. Sensing chromosome bi-orientation by spatial separation of Aurora B kinase from kinetochore substrates. Science 323(5919):1350-3.  *Corresponding author. pdf

Duncan FE†, Chiang T†, Schultz RM, Lampson MA. 2009. Evidence that a defective spindle assembly checkpoint is not the primary cause of maternal age-associated aneuploidy in Mouse eggs. †Equal contribution. Biology of Reproduction 81(4):768-76. pdf

Fuller BG, Lampson MA*, Foley EA, Rosasco-Nitcher S, Le KV, Tobelmann P, Brautigan DL, Stukenberg PT, Kapoor TM. 2008. Midzone activation of Aurora B in anaphase produces an intracellular phosphorylation gradient. Nature 453: 1132-6.  *Shared first author and co-corresponding author. pdf

Kapoor TM, Lampson MA, Hergert P, Cameron L, Cimini D, Salmon ED, McEwen BF, Khodjakov A. 2006. Chromosomes can congress to the metaphase plate prior to bi-orientation. Science 311: 388-91 (Cover). pdf and see Perspective by Heald.

Lampson MA, Kapoor TM. 2005. The human mitotic checkpoint protein BubR1 regulates chromosome-spindle attachments. Nature Cell Biology 7: 93-8. pdf

Lampson MA, Renduchitala K, Khodjakov A, Kapoor TM. 2004. Correcting improper chromosome–spindle attachments during cell division. Nature Cell Biology 6: 232-7 (Cover). pdf and see News & Views by Biggins.

 

See PubMed for a complete list of publications.