Penn Chemistry NMR Facility provides researchers in the Chemistry, Material Science and Engineering department at University of Pennsylvania access to state-of-the-art instrumentation for high resolution NMR spectroscopy. Facility provides users extensive training to use spectrometers wihtout supervision and expert advice/consultation on advanced applications of NMR spectroscopy to solve rsearch problems. At present, the Facility operates 9 high resolution NMR spectrometers (400-600 MHz) of varying capabilities and located in the Chemistry building at the corner of 34th and Spruce street, Philadelphia, PA.
There are six 500 MHz spectrometers configured for observing a wide range of nuclei, with consoles varying from DRX, AVII to AVIII. The 500 MHz probes include several 5 mm Bruker room temperature probes such as DUAL, BBO, BBFO, QNP, and TXI, and a Bruker Helium-cooled cryogenic 5mm DCH probe that is optimized for the highest 13C sensitivity. The lower field spectrometers consist of a two-channel AVIII 400 MHz NMR and a three-channel NEO 400 MHz NMR. In addition to 5 mm Bruker X-nuclei-optimized IProbe and BBFO probes, a Bruker 5mm inverse triple resonance TBI probe that is designed to observe 1H with 13C/BB decoupling is also available for the 400 MHz spectrometers. The highest field spectrometer is a Bruker AVANCE NEO 600 MHz NMR equipped with a Bruker 5 mm X-nuclei-optimized BBO nitrogen-cooled Prodigy Cryoprobe, as well as a Bruker 3mm TXI probe and a Bruker 5mm TXI probe that are 1H optimized with 13C/15N decoupling. The SampleCase on the NEO400 and NEO 600 allows automation.