The NEO600 has been upgraded with a Prodigy cryoprobe. This probe is a liquid nitrogen cooled BBO probe with enhanced sensitivity of approximately 5x compared to our room temperature probe. It has also been equipped with a 24 sample autosampler for automation. The NEO600 will run on the automated Bruker software IconNMR on a 24hr basis, unless there are experimental needs that would require a manual acquisition.