Catalytic Antibodies-Hirschmann/Smith/Benkovic Collaboration

Referenced Publications:
R. Hirschmann, A. B. Smith, III, C. M. Taylor, P. A. Benkovic, S. D. Taylor, K. M. Yager, P. A. Sprengeler, and S. Benkovic. Peptide Syntheses Catalyzed by an Antibody Containing a Binding Site for Variable Amino Acids. Science 1994, 265, 234-237.
A. B. Smith, III, C. Taylor, S. J. Benkovic, and R. Hirschmann. Peptide Bond Formation Via Catalytic Antibodies: Synthesis of a Novel Phosphonate Diester Hapten. Tetrahedron. Lett. 1994, 35, 6853-6856.
Hirschmann, Ralph; Yager, Kraig M.; Taylor, Carol M.; Moore, William; Sprengeler, Paul A.; Witherington, Jason; Phillips, Barton W.; Smith, Amos B.. III. Phosphonyltriethylammonium Salts: Novel Reactive Species for the Synthesis of Phosphonate Esters and
Smithrud, David B.; Benkovic, Patricia A.; Benkovic, Stephen J.; Taylor, Carol M.; Yager, Kraig M.; Witherington, Jason; Philips, Barton W.; Sprengeler, Paul A.; Smith, Amos B., III; Hirschmann, Ralph. Investigations of an Antibody Ligase. Journal of the
Hirschmann, Ralph; Yager, Kraig M.; Taylor, Carol M.; Witherington, Jason; Sprengeler, Paul A.; Phillips, Barton W.; Moore, William; Smith, Amos B., III. Phosphonate Diester and Phosphonamide Synthesis. Reaction Coordinate Analysis by 31P NMR Spectroscopy
D. B. Smithrud, P. A. Benkovic, S. J. Benkovic, V. Roberts, J. Liu, I. Neagu, S. Iwama, B. W. Phillips, A. B. Smith, III, and R. Hirschmann. Cyclic peptide formation catalyzed by an antibody ligase. Proc. Nat. Acad. Sci. 2000, 97, 1953-1958.
S. N. Savinov, R. Hirschmann, S. J. Benkovic and A. B, Smith, III. Investigation of an Antibody-Ligase. Evidence for Strain-Induced Catalysis. Bioorg. Med. Chem. Lett. 2003, 13, 1321-1324.