Full List
The complete list of Professor Smith’s publications [H-index-96] are displayed in reverse chronological order. A search engine allows for searches by the first or last name of authors, keywords in the title and abstract.
Important Notice: Since providing direct access to the original PDF files (by placing them on one’s server to be accessed by the public) is a serious violation of current U.S. copyright laws, the publications below are directly linked to the files residing on the respective publisher’s server. If you or your institution have subscription agreement with these publishers, you will be able to obtain the PDF document by simply clicking on the number of the publication.
| 2023 | |
| 804. | J. Ding, A.B. Smith, III, Total Synthesis of the Reported Structure of Neaumycin G, J. Am. Chem. Soc. Aug. 10, 2023 |
| 803. | M. Gupta, G. Canziani, C. Ang, M. Mohammadi, C.F. Abrams, D. Yang, A.B. Smith III, Irwin Chaiken. Pharmacophore Variants of the Macrocyclic Peptide Triazole Inactivator of HIV-1 Env. |
| 2022 | |
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| 802. | J. Richard, J. Prévost, C. Bourassa, N. Brassard, G. Goyette, H. Medjahed, G. Gendron-Lepage, F. Gaudette, H-C. Chen, W. D. Tobert, A. B. Smith, III, M. Pazgier, M. Dubé, A. Clark, W. Mothers, D. E. Kaufmann, and A. Finzi. Temsavir Blocks HIV-1 Soluble gp120-Induced Immunomodulartory Activities, Cell Rep. Med. |
| 801. | T. Alle, C. Varricchio, Y. Yao, B. Lucero, G. Nzou, S. Demuro, M. Muench, K. D. Vuong, K. Oukoloff, A-S. Cornec, J. Q. Trojanowski, V.M.-Y. Lee, A. B. Smith III, A. Brancale, K. R. Brunden, C. Ballatore, Microtubule-Stabolizing 1,2,4-Triazole[1,5-a]pyridimidines as Candidate Therapeuticis for Neuro-degenerative Tauopathies: Match Molecular Pair Analyses and Computational Studies Reveal New Elements of Structure-Activity Relationships. J, Med. Chem. 2023, 66, 435-459. |
| 800. | C. Fritschi, S. Anang, Z. Gong, M. Mohammadi, J. Richard, C. Bourassa, K. Severino, H. Richter, D. Yang, H-C. Chen, T-J. Chiu, M. Seaman, N. Mandani, C. Abrams, A. Finzi, W.A. Hendrickson, J. Sodroski, A.B. Smith, III. Indoline CD4-mimetic Compounds Mediate Potent and broad HIV-1 Inhibition and Sensitization to Antibody-dependent Cellular Cytotoxicity. PNAS In Press. |
| 799. | K. Matsumoto, T. Kuwata, W. D. Tolbert, J. Richard, S. Ding, J. Prevost, S. Takahama, G. P. Judicata, T. Ueno, H. Nakata, K. Takuya, K. Tsuji, H. Tamamura, A. B. Smith, III, M. Pazgier, A. Finzi, S. Matsushita. Characterization of a Novel CD4 Mimetic Compound YIR-8211 Against Hiv-1 Clinical Isolates. J. Viro. 10.1128/jvi.01638-22. |
| 798. | A. Laumaea, L. Marchitto, G. Beaudoin-Bussières, S. Ding, R. Gasser, D. Chatterjee, G. Gendron-Lepage H. Medjahed, H.-C. Chen, A. B Smith III , H.Ding, J. Kappes, B. Hahn, F. Kirchhoff, J. Richard, R. Duerr, A. Finzi. Small CD4 Mimetics Sensitize HIV-1-Infected Macrophages to Antibody-Dependent Cellular Cytotoxicity. Cell Reports, 42, 111983, Jan. 31, 2023 |
| 797. | C. Chaplain, C. Fritschi, S. Anang, Z. Gong, J. Richard, C. Bourassa, S. Liang, M. Mohammadi, J. Park, N. Madani, J. Sodroski, C. F. Abrams, W. A. Hendrickson and A. B. Smith, III. Structure and Functional Characterization of Indane-core CD4-mimetic Compounds Substituted with Heterocyclic Amines. ACS Med. Chem. Lett. 2023, 14, 51. |
| 796. | J. Prévost, S. Anand, J.K. Rajashekar, J. Richard, G. Goyette, H. Medjahed, G. G. Lepage, H-C. Chen, Y. Chen, J. A. Horwitz, S. Zolla-Pazner, B. F. Haynes, D. R. Burton, F. Kirchhoff, B. H. Hahn, A. B. Smith, III, M. Pazgier, M. C. Nussenzweig, P. Kumar, A. Finzi. HIV-1 Vpu Restricts Fc-Mediated Effector Functions in Vivo, Cell Reports 41,11624, 2022. |
| 795. | S. Anang, J. Richard, C. Bourassa, G. Goyette, T-J. Chiu, H. C. Chen, A. B. Smith, III, N. Madani, A. Finzi, J. Sodroski. Characterization of Human Immunodeficiency Virus (HIV) Envelope Glycoprotein Variants Selected for Resistance to a CD4-Mimetic Compound. J. Virol. 2022; 96 (17): e0063622; doi:10.1128/jvi.00636-22. PMID:35980207. |
| 794. | J. Krischman, M. Marin, Y.-C. Chen, J. Chen, A. Herschhorn, A. B. Smith, III, G. B. Melikyan. SERING5 Restricts HIV-1 Infectivity by Promoting Conformational Changes and Accelerating Functional Inactivation of Env. Viruses, 2022, 14,1388. |
| 793. | D. R. Mattos, X. Wan, J. D. Serrill, M. H. Nguyen, I. R. Humphreys, B. Viollet, A. B. Smith, III, K. L. McPhail, J. E. Ishmael. The Marine-Derived Macrolide Mandelalide A is an Indirect Activator of AMPK. Marine Drugs 2022, 20, 418. Editors Choice |
| 792. | J. Krischman, M. Marin, Y.-C. Chen, J. Chen, A. Herschhorn, A. B. Smith, III, G. B. Melikyan. SERING5 Restricts HIV-1 Infectivity by Promoting Conformational Changes and Accelerating Functional Inactivation of Env. Viruses, 2022, 14,1388. |
| 791. | D. R. Mattos, X. Wan, J. D. Serrill, M. H. Nguyen, I. R. Humphreys, B. Viollet, A. B. Smith, III, K. L. McPhail, J. E. Ishmael. The Marine-Derived Macrolide Mandelalide A is an Indirect Activator of AMPK. Marine Drugs 2022, 20, 418. |
| 790. | S. Ding, I. Ullah, S.-Y. Gong, J. R. Grover, M. Mohammadi, Y. Chen, D. Vézina, G. Beaudoin-Bussières, V. T, Verma, G. Goyette, F. Gaudette, J. Richard, D. Yang, A. B. Smith, III, M. Pazgier, M. Côté, C. Abrams, P. Kumar, W. Mothes, P. D.Uchil, A. Finzi, C. Baron. VE607 Stabilizes SARS-Co-2 Spike in the “BBD-up” Conformation and Inhibits Viral Entry. iScience 25, 104528, July 15, 2022. |
| 789. | R. Bai, A. B. Smith, III, George R. Pettit, E. Hamel. The Interaction of Spongistatin 1 with Tubulin, Arch. Biochem. Biophys. 727 2022 109296. |
| 788. | J. B. Cox, A. A. Kellum, Y. Zhang, B. Li, A. B. Smith. III. Total Synthesis of (-)-Bastimolide A. A Show Case for Type I Anion Relay Chemistry, Angew. Chem. Int. Ed. 2022, e202204884. |
| 787. | Q. Wang, F. Esnault, A. B. Smith III, Ta-J. Chiu, H. T. Nguyen, J. G. Sodroski. Global Increases in Human Immunodeficiency Virus Neutralization Due to Alterations in the Membrane-Proximal External Region of the Envelope Glycoprotein Sensitivity Can be Minimized by Distant State 1-Stabilizating Changes, J. Viro/. 2022 Apr 13;96(7). |
| 786. | H. T. Ngyuen, A. Qualizza, S. Anang, M. Zhao, S. Zou, R. Zhou, Q. Wang, S. Zhang, A. Deshpande, H. Ding, Ta-J. Chiu, A. B. Smith, III, J. C. Kappes, J. G. Sodroski. Functional and Highly Crosslinkable HIV-1 Envelope Glycoproteins Enriched in a Pretrigered Conformation, J. Virol. J. Virol. 2022, Apr. 27;96(8). |
| 785. | R. J. Micikas, A. Acharyya, A.B. Smith, III, F. Gai, Synthesis and Characterization of the Fluorescence Utility of Two Visible-Light-Absorbing Tryptophan Derivatives. Chem. Phys. Lett. 2022, 795. 139553 |
| 784. | S. Ding, S. Y. Gong, J, Grover, M. Mohammadi, Y Chen, D. Vézina, G. Beaudoin-Bussières, V. Verma, G. Goyette, J. Richard, D. Yang, A. B. Smith, III, M. Pazgier, M. Côté, C Abrams, W. Mothes, A. Finzi, C. Baron. Cell Reports. VE607 Stabilizes SARS-CoV-2 Spike In the “RBD-up” Conformation and Inhibits Viral Entry. iScience bioRxiv 2022. |
| 783. | K. J. Brown, M. Nguyen, A. B. Smith, III. Lessons Learned from Laboratory Vaccum Pumb Exhaust Explosion: Discussions and Preventive Strageties, ACS Chemical Health and Safety, 2022, 29, 87-90. |
| 2021 | |
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| 782. | J. Pervost, H. Medjahed, D. Vezina, H-C. Chen, B. H. Hahn, A. B. Smith, III, A. Finzi. HIV-1 Envelope Glycoproteins Protects Infected Cells from ADCC Mediated by Plasma from Infected Individuals. Viruses 2021, 13, 2236. |
| 781. | C. Fritschi, S. Liang, M. Mohammadi, S. Anang, F. Moraca, J. Chen, N. Madani, J. Sodroski, C. Abrams, W. A. Hendrickson, A. B. Smith, III. Identification and validationof gp120 Residue His105 as a Novel Target for HIV-1 Neutralization by Small-Molecule CD4-Mimics, ACS Med.Chem. Letters, 2021, 12, 1824-1831. |
| 780. | S. P. Anand, J. Prevost, J. Descoteaux-Dinell, J. Richard, D. N. Nguyen, H. Medjahed, H-C. Chen, A. B. Smith, III, M. Pazgier, A. Finzi. HIV-1 Envelope Glycoprotein Cell Surface Location Dictates Its Susceptibility to Antibody-Induced Internalization. Viruses. 2021, 13, 1953 |
| 779. | Y. Deng, Y. Zou, C-P. H. Yang, K. N. Houk, A. B. Smith, III. Total Synthesis of (+)-Peniciketals A-B and (-)-Diocollettines A Exploiting a Photoisomerization/Cyclication Union Protocol. J. Org. Chem. 2021, 86, 13583 –13597. |
| 778. | J. K. Rajashekar, J. Richard, J. Beloor, J. Prevost, S. P. Anand, L. Shan, D. Hemdler-Brandstetter, G. Gendron-Lepage, H. Medjahed, F. Gaudette, I. Ullah, A. Peric, D. E. Kaufmann, J. Sodroski, M. Pazgier, R. A. Flavell, J. Park, H.-C. Chen, A. B. Smith, III, A. Finzi, P. Kumar. Modulating the HIV-1 Envelope Glycoprotein Conformation to Decrease the HIV-1 Reservoir. 2021, Cell Host & Microbe, 2021, 29, 1-13. |
| 777. | R. J. Micikas, I. A. Ahmed, A. B. Smith, III, and F. Gai. Tuning the electronic transition energy of indole via substitution: application to identify tryptophan-based chromophores that absorb and emit visible light. Phys. Chem. Chem. Phys 2021, 23, 6433-6437. |
| 776. | R. J. Micikas, A. Acharyya, F. Gai, A.B. Smith, III. A Scalable Synthesis of the Blue Fluorescent Amino Acid, 4-Cyano-Tryptophan, and the Fmoc-Derivative: Utility Demonstrated with the Influenza Matrix-2 Peptide Tetramer. Org. Lett, 2021, 23,1247-1250. |
| 775. | A. Gaffney A. Nangarlia, C. Ang, S. Gossert, A.A. Rashad, M. A. Hossain, C. F. Abrams. A. B. Smith, IIII, I Chaiken. HIV-1 Env-Dependent Cell Killing by Bifunctional Small-Molecule/Peptide Conjugates. ACS Chem. Bio. 2021, 16, 193-204. |
| 774. | K. Oukoloff, G Nzou, C. Varricchio, B. Lucero, T. Alle, J. Kovalevich, L. Monti, A.-S. Cornec, Y. Yao, M. J. James, J. Q. Trojanowski, V. M.-Y. Lee, A. B. Smith, III, A. Brancale, K. R. Brunden and C. Ballatore. Evaluation of Structure-Activity Relationship of Microtubule (MT)-Targeting 1,2,4-Triazolol[1,5,-a]pyrimidines Identifies New Candidates for Neurodegenerative Tauopathies. J. Med. Chem. 2021, 64,1073-1102 |
| 773. | Y. Deng, C-P. H. Yang, and A. B. Smith, III. Enantioselective Total Synthesis of (+)-Peniciketals A and B: Two Architecturally Complex Spiroketals. J. Am. Chem. Soc. 2021,143,1740-1744. |
| 772. | D. Vezina, S.Y. Gong, W. Tolbert, S. Ding, D. Nguyen, G. Gendron-Lepage, B. Melillo, A. B. Smith, III, M. Pazgier and A. Finzi, Stabilizing the HIV-1 Envelope Glycoprotein State 2A Conformation. J. Virol. 2021, 95, 5, e01620-20. |
| 771. | K. T. O’Brien, J. Nadraws and A. B. Smith, III. A New Difluoromethylene Lynchpin/Synthon. Application in Conjunction with Anion Relay Chemistry (ARC) Permits Ready Access to Diverse Difluoromethylene Scaffolds. Org. Lett. 2021, 23,1521-1954. |
| 770. | C. A. Jette, C. O. Barnes, S. M. Kirk, B. Melillo, A. B. Smith, III, P. J. Bjorkman. Cryo-EM structures of HIV-1 trimer bound to CD4-mimetics BNM-III-170 and M48U1 adopt a CD4-bound open conformation. Nat. Commun., 2021, 12, 1950. |
| 769. | Y. Chen, X. Zhang, F. Liu, G. He, J. Zhang, K. N. Houk, A. B. Smith, III, and Y. Liang. The Role of Cul in the Siloxane-Meditated Pd-Catalyzed Cross-Coupling Reactions of Aryl Iodides with Aryl Lithium Reagents: A DFT Analysis. Chinese Chem Lett. 2021 32, 441-444.C, NIHMSID: 1614511. |
| 2020 | |
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| 768. | M. G. Cotticelli, R. Forestieri, S. Xia, S. Joyasawal, T. Lee, K. Xu, A. B. Smith, III, D Huryn, R. B. Wilson. Identification of a Novel Oleic Acid Analog with Protective Effects in Multiple Cellular Models of Friedreich Ataxia. ACS Chem. Neurosci. 2020, 11, 17, 2535-2542. |
| 767. | L. Monti, A-S. Cornec, J. Kovalevich, K. Oukoloff, J. Kovalevich, K. Prijs, T. Alle, K. R. Brunden, A. B. Smith, III, N. El-Sakkary, L. Liu, A. Syed, D. E. Skinner, C. Ballatore, and C. R. Caffrey. Novel Congeners Derived from Microtubule-Active Phenyl-Pyrimidines Produce a Potent and Long-Lasting Paralysis of Schistosoma Mansoni in Vitro. ACS Infectious Diseases. 2020, 64 1073-1102. |
| 766. | A. Laumaea, A. B. Smith, III, J. Sodroski, A. Finzi. Opening the HIV Envelope: Potential of CD4 Mimics as Multifunctional HIV Entry Inhibitors. Curr. Opin. HIV AIDS. 2020, 15, 300-308. |
| 765. | B. Guo, A. Rodriguez-Gabin, A. E. Prota, T. Mühlethaler, N. Zhang, K. Ye, M. O. Steinmetz, S. B. Horwitz, A. B. Smith, III, and H. M. McDaid. Structural Refinement of the Tubulin Ligand (+)-Discodermolide to Attenuate Chemotherapy-Mediated Senescence. Mol. Pharmacol. 2020, 98, 156-167. |
| 764. | G. Beaudoin-Bussieres, J. Prevost, G. Gendron-Lepage, B. Melillo, J. Chen, A. B. Smith, III, M. Pazgier, and A. Finzi. Elicitation of Cluster A and Co-Receptor Binding Site Antibodies are Required to Eliminate HIV-1 Infected Cells. Microorganisms. 2020, 8(5), 710. |
| 763. | G. Sarikaki, N. Chistoforidou, N. Gaboriaud-Kolar, A. B. Smith, III, I. K. Kostakis, A-L. Skaltsounis. A Biomimetic Synthesis of Olecanthal, Oleacein and Their Analogues Starting from Oleuropein, A Major Compound of Olive Leaves. Journal of Natural Products. 2020. |
| 762. | J. Prevost, W. D. Tolbert, H. Medjahed, R. T. Sherburn, N. Madani, D. Zoubchenok, G. Gendron-Lepage, A. E. Gaffney, M. C. Grenier, S. Kirk, N. Vergara, C. Han, B. T. Mann, A. L. Chenine, A. Ahmed, I. Chaiken, F. Kirchhoff, B. Hahn, H. Haim, C. Abrams, A. B. Smith, III, J. Sodroski, M. Pazgier, A. Finzi. The HIV-1 Env gp120 Inner Domain Shapes the Phe43 Cavity. mBio.asm.org. 2020, 11 (3), e00280-20. |
| 761. | M. Lu, X. Ma, N. Reichard, D. S. Terry, J. Arthos, A. B. Smith, III, J. G. Sodroski, S. C. Blanchard, W. Mothes. Shedding-resistant HIV-1 envelope glycoproteins adopt downstream conformations but remain responsive to conformation-specific ligands. J. Virol. 2020. |
| 760. | S. Zou, S. Zhang, A. Gaffney, H. Ding, M. Lu, J. R. Grover, M. Farrell, H. T. Nguyen, C. Zhao, S. Anang, M. Zhao, M. Mohammadi, M. C. Blanchard, C. Abrams, N. Madani, W. Mothes, J. C. Kappes, A. B. Smith, III, and J. Sodroski. Long-Acting BMS-378806 Analogues Stabilize the State-1 Confirmation of the Human Immunodeficiency Virus (HIV-1) Envelope Glycoproteins. J. Virol. 2020, 94(10), e00148-20. |
| 759. | Y. Deng, A. B. Smith, III. Evolution of the Anion Relay Chemistry: Construction of Architecturally Complex Natural Products. Accounts of Chemical Research. 2020, 53, 988-1000. |
| 758. | M. C. Grenier, S. Ding, D. Vézina, J. Chapleau, W. Tolbert, M. Pazgier, A. Finzi, and A. B. Smith, III. Optimization of Small Molecules that Sensitize HIV-1 Infected Cells to Antibody Dependent Cellular Cytotoxicity. Med. Chem. Lett. 2020, 11, 371-378. |
| 757. | A. B. Smith, III. A Tribute to Professor Kaoru Fuji on the Occasion of His 80th Birthday. Hetero-cycles. 2020, 101, 1-3. |
| 2019 | |
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| 756. | J. Chen, J. Park, S. M. Kirk, H-C. Chen, X. Li, D. J. Lippincott, B. Melillo, and A. B. Smith, III. Development of an Effective Scalable Enantioselective Synthesis of the HIV-1 Entry Inhibitor BNM-III-170 as the Bis-Trifluoroacetate Salt. Org. Process Res. Dev. 2019, 23, 2464-2469. |
| 755. | Y. Deng, M. D. Nguyen, Y. Zou, K. N. Houk, A.B. Smith, III. Generation of Dithianyl and Dioxolanyl Radicals Using Photoredox Catalysis: Application in the Total Synthesis of the Danshenspiroketallactones via Radical Relay Chemistry. Org. Lett. 2019, 21(6), 1708-1712. |
| 754. | A. Gaffney, A. Nangarlia, S. Gossert, A. A, Rashad, M. A. Hossain, C. F. Abrams, A. B. Smith, III, and I. Chaiken. Irreversible HIV-1 Inactivation Employing a Small-Molecule Dual-Action Virolytic Entry Inhibitor Strategy. ChemRxiv. 2019. |
| 753. | S. Ding, M. C. Grenier, W. D. Tolbert, D. Vézina, R. Sherburn, J. Richard, J. Prévost, J. Chapleau, G. Gendron-Lepage, H. Medjahed, C. Abrahms, J. Sodroski, M. Pazgier, A. B. Smith, III, and A. Finzi. A New Family of Small Molecule CD4-Mimetic Compounds Contact the Highly Conserved Aspartic Acid 368 of HIV-1 gp120 and Mediates ADCC. J. Virol. 2019, 93, e01325-19. |
| 752. | K. T. O’Brien and A. B. Smith, III. Merging Asymmetric [1,2]-Additions of Lithium Acetylides to Carbonyls with Type II Anion Relay Chemistry (ARC). Org. Lett. 2019, 21,7655-7659. |
| 751. | C. Zhao, A. M. Princiotto, H. T. Nguyen, S. Zou, M. L. Zhao, S. Zhang, A. Herschhorn, M. Farrell, K. Pahil, B. Melillo, S. V. Sambasivarao, C. Abrams, A. B. Smith, III, N. Madani, and J. Sodroski. Strain-Dependent Activation and Inhibition of Human Immunodeficiency Virus (HIV-1) Entry by a Specific PF-68742 Stereoisomer. J. Virol. 2019, 93 (21), e01197-19. |
| 750. | Y. Zou, X.-S. Xue, Y. Deng, A. B. Smith, III, and K. N. Houk. Factors Controlling Reactivity in the Hydrogen Atom Transfer and Radical Addition Steps of A Radical Relay Cascade. Org. Lett. 2019, 21, 5894-5897. |
| 749. | M. Lu, X. Ma, L. R. Castillo-Menendez, J. Gorman, N. Alsahafi, U. Ermel, D. S. Terry, M. Chambers, D. Peng, B. Zhang, T. Zhou, N. Reichard, K. Wang, J. R. Grover, B. P. Carman, M. R. Gardner, I. Nikić-Spiegal, A. Sugawara, J. Arthos, E. A. Lemke, A. B. Smith III, M. Farzan, C. Abrams, J. B. Munro, A. B. McDermott, A. Finzi, P. D. Kwong, S. C. Blanchard, J. G. Sodroski, and W. Mothes. Associating HIV-1 Env Trimer Structured with Conformational States Defined by smFRET. Nature. 2019, 568, 415-419. |
| 748. | N. Alsahafi, N. Bakouche, M. Kazemi, J. Richard, S. Ding, S. Bhattacharyya, D. Das, S. P. Anand, J. Prévost, W. D. Tolbert, H. Lu, H. Medjahed, G. Gendron-Lepage, G. G. O. Delgado, S. Kirk, B. Melillo, W. Mothes, J. Sodroski, A. B. Smith, III, D. E. Kaufmann, X. Wu, M. Pazgier, I. Rouiller, A. Finzi, and J. B. Munro. An Asymmetric Opening of HIV-1 Env is Required for Anti-Cluster A Antibody Binding. Cell Host Microbe. 2019, 25, 578-587. |
| 747. | S. P. Anand, J. Prévost, S. Baril, J. Richard, H. Medjahed, J-P. Chapleau, W. D. Tolbert, S. Kirk, A. B. Smith, III, B. D. Wines, S. J. Kent, M. Hogarth, M. S. Parsons, M. Pazgier, A. Finzi. Two Families of Env Antibodies Efficiently Engage Fc-gamma Receptors and Eliminate HIV-1-Infected Cells. J. of Virol. 2019, 93 (3), pii:e01823-18. |
| 2018 | |
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| 746. | A.B. Smith, III. Farewell and Thanks. Org. Lett. 2018, 20 (24), 7747. |
| 745. | B. Zhang, Y. Yao, A. Cornec, K. Oukoloff, M. James, P. Koivula, J. Q. Trojanowski, A. B. Smith, III, V. M-Y. Lee, C. Ballatore, and K. R. Brunden. A Brain-Penetrant Triazolopyrimidine Enhances Microtubule-Stability and Reduces Axonal Dysfunction and Tau Pathology in a Mouse Tauopathy Model. Molecular Neurodegeneration. 2018, 13 (1), 59. |
| 744. | W. B. Tolman, S. Miller, P. Chirik, A. B. Smith, III. Editorial: Straddling the Rooftop: Finding a Balance between Traditional and Modern Views of Chemistry. Org. Lett. 2018, 20, 5075-5081 |
| 743. | L. Monti, S. Wang, K. Oukoloff, A.B. Smith, III, K. R. Bruden, C. R. Caffrey, and C. Ballatore. Brain-penetrant, triazolopyrimidine and phenylpyrimidine microtubule-stabilizers as potential leads to treat Human African Trypanosomiasis. Bioorganic & Medicinal Chemistry Letters. 2018, 13, 1751-1754. |
| 742. | Y. Zou, X. Li, Y. Yang, S. Berritt, J. Melvin, S. Gonzales, M. Spafford, and A. B. Smith, III. Total Synthesis of (–)-Nodulisporic Acids D, C and B: Evolution of a Synthetic Strategy. J. Am. Chem. Soc. 2018, 140 (30), 9502-9511. |
| 741. | N. Alsahafi, S. P. Anand, L. Castillo-Menendez, M. M. Verly, H. Medjahed, J. Prévost, A. Herschhorn, A. Schön, B. Melillo, E. Freire, A. B. Smith, III, J. Sodroski, A. Finzi. SOSIP Changes Affect Human Immunodeficiency Virus (HIV-1) Envelope Glycoprotein Conformation and CD4 Engagement. J. Viro. 2018. |
| 740. | Y. Ai, M. V. Kozytska, Y. Zou, A. S. Khartulyari and A. B. Smith, III. Total Synthesis of the Marine Phosphomacrolide, (–)-Enigmazoles A, Exploiting Multicompnent Type I Anion Relay Chemisty (ARC) in Conjunction with a Late-Stage Petasis – Ferrier Union/Rearrangement. J. Org. Chem. 2018, 138, 3675-3678. |
| 739. | K. Oukoloff, Y. Yao, A. Cornec, M. James, J. Kovalevich, J. Q. Trojanowski, V. M.-Y. Lee, A. B. Smith, III, K. R. Bunden, and C. Ballatore. Design, Synthesis and Evaluation of Photoactivatable Derivatives of Microtubule (MT)-active [1,2,4]triazolo [1,5-a]pyramidines. Bioorg. Med. Chem. Lett. 2018, 28, 2180-2183. |
| 738. | 738. F. Moraca, D. Rinaldo, A. B. Smith, III, and C. F. Abrams. Specific Noncovalent Interactions Determine Optimal Structure of a Buried Ligand Moiety: QM/MM and Pure QM Modeling of Complexes of the Small-Molecule CD4 Mimetics and HIV-1 gp120. Chem. Med. Chem., 2018, 13, 627-633. |
| 737. | N. Madani, A. M. Princiotto, L. Mach, S. Ding, J. Prevost, J. Richard, B. Hora, L. Sutherland, C.A. Zhao, B. P. Conn, T. Bradley, M. Anthony Moody, B. Melillo, A. Finzi, B. Haynes, A. B. Smith, III, S. Santra and J. Sodroski. A CD4-Mimetic Compound Enhances Vaccine Efficacy Against Stringent Immunodeficiency Virus Challenge. Nature Commun. 2018, 9, 2363. |
| 736. | A. M. Princiotto, V. D. Vrbanac, B. Melillo, J. Park, A. M. Tager, A. B. Smith, III, J. Sodroski and N. Madani. A Small-Molecule CD4 Mimetic Compound Protects BLT-mice From Human Immunodeficiency Virus Infection. J. Inf. Disease. 2018, 218(3), 471-475. |
| 735. | M. H. Nguyen, M. Imanishi, T. Kurogi, X. Wan, J. E. Ishmael, K. L. McPhail and A. B. Smith III. Synthetic Access to the Mandelide Family of Macrolides: Development of an Anion Relay Chemistry Strategy. J. Org. Chem. 2018, 83, 4287-4306. |
| 734. | C. Nadaradjane, C. P. H. Yang, A. Rodriguez-Gabin, K. Ye, K. Sugawasa, O. Atasoylu, A. B. Smith, III, S. B. Horwitz, and H. M. McDaid. Improved Dose-Response of (+)-Discodermolide-Taxol Hybrid Congeners. J. Nat. Prod. 2018. 81. 607-615. |
| 733. | S.L. Mooberry, D.G.I. Kingston, A.B. Smith, III, S.M. Swanson, M.C. Wani. Editorial: Special Issue in Honor of Professor Susan Band Horwitz. J. Nat. Prod. 2018. 81, 449-500. |
| 732. | B. Parajuli, K. Acharya, H. C. Bach, B. Parajuli, A. B. Smith, III, C. F. Abrams and I. Chaiken. Restricted HIV-1 Env Glycan Engagement by Lectin-Reengineered DAVEI Protein Chimera is Sufficient for Lytic Inactivation of the Virus. Biochem. J. 2018, 5, 931-957. |
| 731. | A.B. Smith, III. Obituary – Frank Mallory, Chem. & Eng. News, 2018, p.32 |
| 730. | A. M. Hunter and A. B. Smith, III. Update on Data Standards at Organic Letters. Org. Lett. 2018, 20, 1481-1482. |
| 729. | Y. Zou and A. B. Smith, III. Total Synthesis of Architecturally Complex Indole Terpenoids: Strategic and Tactical Evolution. J. Antibiotics. 2018, 71, 185-204. |
| 728. | A.B. Smith, III. Editorial: Twenty Year of Organic Letters, A Look Back…and Forward. Org. Lett. 2018, 20, 1-3. |
| 2017 | |
|---|---|
| 727. | T. D. Montgomery and A. B. Smith, III. α-Silyl Amides: Effective Bifunctional Type I Linchpins for Anion Relay Chemistry. Org. Lett. 2017, 19, 6216-6219. |
| 726. | H. Han and A. B. Smith, III. Anion Relay Chemistry: The Development of an Effective Diastereoselective [3+2} Annulation Tactic Exploiting an Aldol/Brook Rearrangement/Cyclization Cascade. Angew. Chem. Int. Ed. 2017, 56, 14102-14106. |
| 725. | Q. Liu, Y. Deng, and A. B. Smith III. Total Synthesis of (–)-Nahuoic Acid Ci (Bii). J. Am. Chem. Soc. 2017, 82, 1156-11071. |
| 724. | P. Lassalas, K. Oukoloff, V. Makani, M. James, V. Tran, M. Yao, L. Huang, K. Vijayendran, L. Monti, J. Q. Trojanowski, V. M.-Y. Lee, M. C. Kozlowski, A. B. Smith, III, K. R. Brunden and C. Ballatore. Evaluation of Oxetan-3-ol, Thietan-3-ol and Derivatives Thereof as Potential Bio-isosteres of the Carboxylic Acid Functional Group. ACS Med. Chem. Lett. 2017. 8, 864-868. |
| 723. | Y. Deng, Q. Liu and A. B. Smith, III. Oxidative [1,2]-Brook Rearrangements Exploiting Single-Electron Transfer: Photoredox-Catalyzed Alkylations and Arylations. J. Am. Chem. Soc. 2017, 139, 9487-9490. |
| 722. | M. Nguyen. K. T. O’Brien and A. B. Smith, III. Design, Synthesis and Application of Polymer-Supported Silicon Transfer Agents for Cross-Coupling Reactions with Organolithium Reagents. J. Org. Chem. 2017, 82, 11056-11071. |
| 721. | M. Nazari, J. D. Serrill, M. Nguyen, C. Anklin, X. Wan, D. A. Gallegos, A. B. Smith, III, J. E. Ishmael and K. L. McPhail. New Mandelalides Expand a Macrolide Series of Mitochondrial Inhibitors. ACS Chem Bio 2017, 60, 7850-7862. |
| 720. | A. Herschhorn, C. Gu, F. Moraca, X. Ma, M. Farrell, A. B. Smith, III, M. Pancera, P. Kwong, A. Schon, E. Freire, C. Abrams, S. C. Blanchard, W. Mothes and J. G. Sodroski. The 20-21 of gp120 is a Regulatory Switch for HIV-1 Env Conformational Transitions. Nat. Commun. 2017. (doi:10.1038/S41467-017-01119w). |
| 719. | A.-S. Cornec, L. Monti, J. Kovalevich, V. Makani, M. J. James, K. G. Vijayendran, K. Oukoloff, Y. Yao, V. M.-Y. Lee, J. Q. Trojanowski, A. B. Smith, III, K. R. Brunden and C. Ballatore. Multi-targeted Imidazoles as Therapeutic Leads for Alzheimer’s Disease. J. Med. Chem. 2017, 60, 5120-5145. |
| 718. | J. Richard, J. Prévost, B. Von Bredow, S. Ding, M. Coutu, N. Brassard, B. Melillo, F. Bibollet-Ruche, B. H. Hahn, D. E. Kaufmann, A. B. Smith, III, J. Sodroski, D. Sauter, F. Kirchhoff, K. Gee, S. J. Neil, D. T. Evans and A. Finzi. BST-2 Expression Modulates Small CD4 Mimetics Sensitization of HIV-1-infected Cells to ADCC. J. Virol. 2017, 91, e00219-17. |
| 717. | J. Johnson, Y. Zhai, N. Espy, H. Salimi, N. Espy, N. Eichelberger, O. DeLeon, Y. O’Malley, J. Courter, A. B. Smith, III, N. Madani, J. Sodroski and H. Haim. Induction of a Tier-1-like Phenotype in Diverse Tier-2 Isolates by Agents that Guide HIV-1 Env to Perturbation-sensitive, Non-native States. J. Virol. 2017, 91, e00174-17. |
| 716. | R. M. Abaskharon, S. P. Brown, W. Zhang, J. Chen, A. B. Smith, III and F. Gai. Isotope-Labeled Aspartate Sidechain as a Non-Perturbing Infrared Probe: Application to Investigate the Dynamics of a Carboxylate Buried Inside a Protein. Chem Phys Lett. 2017, 683, 193-198. |
| 715. | Q. Liu, Y. Chen, X. Zhang, K. N. Houk and A. B. Smith, III. Type II Anion Relay Chemistry: Conformational Constraints to Achieve Effective [1,5]-Vinyl Brook Rearrangements. J. Am. Chem. Soc. 2017, 139, 8710-8717. |
| 714. | A. E. Prota, K. Bargsten, M. Redondo, A. B. Smith, III, I. Paterson, S. B. Horwitz, J. F. Diaz and M. O. Steinmetz. Structural Basis of Microtubule Stabilization by Discodermolide. Chem. Bio. Chem. 2017, 18, 905-909. |
| 713. | B. Pacheco, N. Alsahafi, O. Debbeche, S. Ding, J.-P. Chapleau, A. Herschhorn, N. Madani, A. Princiotto, C. Gu, X. Zeng, Y. Mao, A. B. Smith, III, J. Sodroski and A. Finzi. Residues in the gp41 Ectodomain Regulate HIV-1 Envelope Glycoprotein Conformational Transitions Induced by gp120-directed Inhibitors. J. Virol. 2017, 92, e-2219-16. |
| 712. | C. Ballatore, K. R. Brunden, J. Q. Trojanowski, V. M.-Y. Lee and A. B. Smith, III. Non-naturally Occurring Small Molecule Microtubule-stabilizing Agents: A Potential Tactic for CNS-directed Therapies. ACS Chem. Neuro. 2017, 8, 5-7. |
| 711. | N. Madani, A. M. Princiotto, C. Zhao, F. Jahanbakhshsefidi, M. Mertens, A. Herschhorn, B. Melillo, A. B. Smith, III and J. Sodroski. Activation and Inactivation of the Human Immunodeficiency Virus Envelope Glycoprotein Trimers by CD4-Mimetic Compounds. J. Virol. 2017, 91, e01880-16. |
| 710. | A. B. Smith, III. Organic Letters Update. Org. Lett. 2017, 19, 1. (Not NIH Funded). |
| 2016 | |
|---|---|
| 709. | K. R. Brunden, V. M.-Y. Lee, A. B. Smith, III, J. Q. Trojanowski and C. Ballatore. Altered Microtubule Dynamics in Neurodegenerative Disease: Therapeutic Potential of Microtubule-Stabilizing Drugs. Neurbiol. Dis. 2016, 105, 328-335 |
| 708. | W. Xu, X. Wang, A. M. Tocker, P. Huang, M. E. A. Reith, L.-Y. Liu-Chen. A. B. Smith, III and S. Kortagere. Functional Characterization of a Novel Series of Biased Signaling Dopamine D3 Receptor Agonists. ACS Chem Neurosci 2016. (ASAP). DOI: 10.1021/acschemneuro.6b00221. |
| 707. | C. Ballatore, A. B. Smith, III, V. M.-Y. Lee, J. Q. Trojanowski and K. R. Brunden. Microtubule-Stabilizing Agents for Alzheimer’s and Other Tauopathies. Top. Med. Chem. 2017, 8, 5-7. |
| 706. | S. Ding, M. M. Verly, A. Princiotto, N. Brassard, B. Melillo, A. M. Moody, T. Bradley, D. Easterhoff, B. H. Hahn, D. E. Kaufmann, N. Madani, A. B. Smith, III, B. Haynes, J. Sodroski and A. Finzi. Small-Molecule CD4 Mimetics Sensitize HIV-1-infected Cells to Antibody-Dependent Cellular Cytotoxicity by Antibodies Elicited by Multiple Envelope Glycoprotein Immunogens in Nonhuman Primates. Aids Res. Hum. Retroviruses 2016, 33, 428-431. |
| 705. | T. Bradley, A. Trama, N. Tumba, E. Gray, X. Lu, N. Madani, F. Jahanbakhsh, A. Eaton, S.-M. Xia, R. Parks, K. E. Lloyd, L. L. Sutherland, R. M. Scearce, C. M. Bowman, S. Barnett, S. S. Abdool-Karim, S. Boyd, B. Melillo, A. B. Smith, III, J. Sodroski, T. B. Kepler, S. M. Alam, F. Gao, M. Bonsignori, H.-X. Liao, M. A. Moody, D. Montefiori, S. Santra, L. Morris and B. F. Haynes. Amino Acid Changes in the HIV-1 gp41 Membrane Proximal Region Control Virus Neutralization Sensitivity. E Bio Medicine 2016, 12, 196-207. |
| 704. | V. Makani, B. Zhang, H. Han, Y. Yao, P. Lassalas, K. Lou, I. Paterson, V. M-Y. Lee, J. Q. Trojanowski, C. Ballatore, A. B. Smith, III and K. R. Brunden. Evaluation of the Brain-Penetrant Microtubule-Stabilizing Agent, Dictyostatin, in the PS19 Tau Transgenic Mouse Model of Tauopathy. Acta Neuropathologica 2016, 4, 106. |
| 703. | J. Richard, B. Pacheco, N. Gohain, M. Veillette, S. Ding, N. Alsahafi, W. D. Tolbert, J. Prévost, J.-P. Chapleau, M. Coutu, M. Jia, N. Brassard, J. Park, J. R. Courter, B. Melillo, L. Martin, C. Tremblay, B. H. Hahn, D. E. Kaufmann, X. Wu, A. B. Smith, III, J. Sodroski, M. Pazgier and A. Finzi. Co-Receptor Binding Site Antibodies Enable CD4-Mimetics to Expose Conserved Anti-Cluster A ADCC Epitopes on HIV-1 Envelope Glycoproteins. E Bio Medicine 2016, 12, 208-218. |
| 702. | C. Ballatore, A. B. Smith, III, V. M.-Y. Lee, J. Q. Trojanowski, and K. R. Brunden. Chapter 11- Microtubule Stabilization A2 in “Developing Therapeutics for Alzheimer’s Disease,” M.S. Wolfe, Ed. Elsevier. Boston, Academic Press. 305-326. 2016. |
| 701. | F. Moraca, K. Acharya, B. Melillo, A. B. Smith, III, I. Chaiken and C. F. Abrams. Computational Evaluation of HIV-1 gp120 Conformations of Soluble Trimeric gp140 Structures as Targets for De Novo Docking of First and Second Generation of Small-Molecule CD4 Mimetics. J. Chem. Inf. Model. 2016, 56, 2069-2079. |
| 700. | A. Hershhorn, X. Ma, C. Gu, D. Ventura, L. Castillo-Menendez, B. Melillo, D. S. Terry, A. B. Smith, III, S. Blanchard, J. B. Munro, W. Mothes, A. Finzi and J. Sodroski. Release of gp120 Restraints Leads to an Entry-Competent Intermediate State of the HIV-1 Envelope Glycoproteins. mBio. 2016, 7, 01598-16. |
| 699. | C. Ballatore, A. B. Smith, III, V. M.-Y. Lee, J. Q. Trojanowski, and K. R. Brunden (2016) Chapter 11 – Microtubule Stabilization A2 in “Developing Therapeutics for Alzheimer’s Disease,” M.S. Wolfe, Ed. Boston, Academic Press: 305-326. |
| 698. | P. Lassalas, B. Gay, C. Lasfargeas, M. James, V. Tran, K. Vijayendran, K. Brunden, M. Kozlowski, C. Thomas, A. B. Smith, III, D. Huryn and C. Ballatore. Structure Property Relationships of Carboxylic Acid Isosteres. J. Med. Chem. 2016, 59, 3183-3203. |
| 697. | N. Madani, A. M. Princiotto, D. Easterhoff, T. Bradley, K. Luo, W. B. Williams, H.-X. Liao, M. A. Moody, G. E. Phad, N. V. Bernat, B. Melillo, A. B. Smith, III, G. B. K. Hedestam, B. Haynes and J. Sodroski. Antibodies Elicited by Multiple Envelope Glycoprotein Immunogens in Primates Neutralize Primary Human Immunodeficiency Viruses (HIV-1) Sensitized by CD4-Mimetic Compounds. J. Virol. 2016, 90, 5031-5046. |
| 696. | J. Kovalevich, A.-S. Cornec, Y. Yao, M. James, A. Crowe, V. M.-Y. Lee, J. Q. Trojanowski, A. B. Smith, III, C. Ballatore and K. R. Brunden. Characterization of pyrimidine-containing molecules with differential microtubule-stabilizing activities: Potential therapeutic agents for Alzheimer’s disease and related neurodegenerative tauopathies. J Pharmacol Exp Ther 2016. 357, 432-450. |
| 695. | Q. Liu, C. An, K. TenDyke, H. Cheng, Y. Y. Shen, A. T. Hoye and A. B. Smith, III. Design, Synthesis, and Evaluation of Ircinastatin Analogues: Simplification of the Tetrahydropyran Core and C(11) Substituents. J. Org. Chem. 2016, 81, 1930-1942. |
| 694. | J. Richard, M. Veillette, S. Ding, D. Zoubchenok, N. Alsahafi, M. Coutu, N. Brassard, J. Park, J. R. Courter, B. Melillo, A. B. Smith, III, G. M. Shaw, B. H. Hahn, J. Sodroski, D. E. Kaufmann and A. Finzi. Small CD4 Mimetics Prevent HIV-1 Uninfected Bystander CD4+ T Cell Killing Mediated by Antibody-dependent Cell-mediated Cytotoxicity. E. Bio Medicine 2016, 3, 122-134. |
| 693. | M. H. Nguyen, M. Imanishi, T. Kurogi and A. B. Smith, III. Total Synthesis of (–)-Mandelalide A Exploiting Anion Relay Chemistry (ARC): Identification of a Type II ARC/CuCN Cross-Coupling Protocol. J. Am. Chem. Soc. 2016. 11, 3675-3678. |
| 692. | L. Penazzi, C. Tackenberg, A. Ghori, N. Golovyashkina, B. Niewidok, K. Selle, C. Ballatore, A. B. Smith, III, L. Bakota, R. Brandt. Aβ-mediated spine changes in the hippocampus are microtubule-dependent and can be reversed by a subnanomolar concentration of the microtubule-stabilizing agent epothilone D. Neuropharmacology. 2016, 105, 84-95. |
| 691. | B. Melillo, S. Liang, J. Park, A. Schon, J. R. Courter, J. M. LaLonde, D. J. Wendler, A. M. Princiotto, M. S. Seaman, E. Freire, J. Sodroski, N. Madani, W. A. Hendrickson and A. B. Smith, III. Small-Molecule CD4-Mimics: Structure-Based Optimization of HIV-1 Entry Inhibition. ACS Med Chem Lett 2016, 26, 330-334. |
| 690. | W. Zhang, B. N. Markiewicz, R. S. Doerksen, A. B. Smith, III and F. Gai. C≡C Stretching Vibration of 5-Cyanotryptophan as an Infrared Probe of Protein Local Environment: What Determines its Frequency? Phys. Chem. Chem. Phys. 2016, 18, 7027-7034. |
| 689. | D. Martinez-Solorio, B. Melillo, L. Sanchez, Y. Liang, E. Lam, K. N. Houk and A. B. Smith, III. Design, Synthesis and Validation of an Effective, Reusable Silicon-Based Transfer Agent for Room-Temperature Pd-Catalyzed Cross-Coupling Reactions of Aryl and HeteroAryl Chlorides with Readily Available Aryl Lithium Reagents. J. Am. Chem. Soc. 2016, 138, 1836-1839. |
| 688. | M. Farrell, B. Melillo, and A. B. Smith, III. Type II Anion Relay Chemistry: Exploiting Bifunctional Weinreb Amide Linchpins for the One-Pot Synthesis of Differentiated 1,3-Diketones, Pyrans and Spiroketals. Angew. Chem. Int. Ed. 2016, 55, 232-235. |
| 687. | C. Delépine, H. Meziane, J. Nectoux, M. Opitz, A. B. Smith, III, C. Ballatore, Y. Saillour, O. Feraud, Q. Chang, E. Cunningham Williams, M. Dahan, A. Duboin, P. Billuart, Y. Herault, T. Bienvenu. Altered Microtubule Dynamics and Vesicular Transportation in Mouse and Human MeCP2-Deficient Astrocytes. Hum Mol Gen. 2016, 25, 146-157. |
| 686. | W. S. Lee, J. Richard, M. Lichtfuss, A. B. Smith, III, J. Park, J. R. Courter, B. N. Melillo, J. G. Sodroski, D. E. Kaufmann, A. Finzi, M. S. Parsons and S. J. Kent. Antibody-Dependent Cellular Cytotoxicity Against Reactivated HIV-1-Infected Cells. J. Virol. 2016. 2016, 90, 2021-2030. |
| 2015 | |
|---|---|
| 685. | N. Golovyashkina, L. Penazzi, C. Ballatore, A. B. Smith, III, L. Bakota and R. Brandt. Region-specific dendritic simplification induced by Aβ, mediated by tau via dysregulation of microtubule dynamics: a mechanistic distinct event from other neurodegenerative processes. Mol Neurodegener. 2016, 10:60. PMC4634596. |
| 684. | B. Melillo, M. Z. Chen, R. Forestieri and A. B. Smith, III. An Effective Bifunctional Aldehyde Linchpin for Type II Anion Relay Chemistry: Development and Application to the Synthesis of a C16-C29 Fragment of Rhizopodin. Org. Lett. 2015, 17, 6242-6245. |
| 683. | Y. Ai, M. V. Kozytska, Y. Zou, A. S. Khartulyari and A. B. Smith, III. Total Synthesis of (–)-Enigmazole A. J. Am. Chem. Soc. 2015, 137, 15426-15429. (Also see: E. Carreira, M. Westphal, Synfacts 2016, 12, 0117.) https://www.thieme-connect.com/products/ejournals/pdf/10.1055/s-0035-1561117.pdf |
| 682. | H. Han and A. B. Smith, III. Total Synthesis of (–)-Secu’amamine A Exploiting Type II Anion Relay Chemistry. Org. Lett. 2015, 17, 4232-4235. |
| 681. | A. M. Hunter and A. B. Smith, III. Editorial; Review of Supporting Information at Organic Letters. Org. Lett., 2015, 17, 2867-2869 (Not NIH Funded). |
| 680. | G. Adams, A. B. Smith, III. The Chemistry of the Akuammiline Alkaloids in “The Alkaloids.” H.-J. Knolker, Ed., Vol. 76. Elsevier, New York, NY. 2016. DOI: 10.1016/bs.alkal.2015.08.001 |
| 679. | B. Melillo, R. M. Kohli and A. B. Smith, III. The 2014 Benjamin Franklin Medal in Chemistry Presented to Christopher T. Walsh. J. Franklin. 2015. |
| 678. | Y. Zou, J. E. Melvin, S. S. Gonzales and A. B. Smith, III. Total Synthesis of (–)-Nodulisporic Acid. J. Am. Chem. Soc. 2015, 137, 7095-7098. |
| 677. | A. Sokolsky, M. Cattoen and A. B. Smith, III. Synthesis of a C(1)-C(23) Fragment for Spirastrellolide E: Development of a Mechanistic Rationale for Spiroketalization. Org. Lett. 2015, 17, 1898-1901. |
| 676. | A.-S. Cornec, M. James, J. Kovalevich, J. Q. Trojanowski, V. M.-Y. Lee, A. B. Smith, III, C. Ballatore, and K. R. Brunden. Pharmacokinetic, pharmacodynamic and metabolism studies of a brain retentive microtubule (MT)-stabilizing triazolopyrimidine. Bioorg. Med. Chem. Lett. 2015, 25, 4980-4982. PMC4569539. |
| 675. | S.P. Brown and A. B. Smith, III. Peptide/Protein Stapling and Unstapling: Introduction of s-Tetrazine, Photochemical Release, and Regeneration of the Native Peptide/Protein. J. Am. Chem. Soc. 2015, 137, 4034-4037. PMC4394111. |
| 674. | A. Naini, Y. Muthukumar, A. Raja, R. Franke, I. Harrier, A. B. Smith, III, D. Lee, R. E. Taylor, F. Sasse and M. Kalesse. The Synthesis of Desepoxy-isotedanolide and Its Biological Evaluation in Comparison with Desepoxy-tedanolide. Angew. Chem. Int. Ed. 2015, 54, 6935-6939. (Not NIH Funded). |
| 673. | J. Richard, M. Veillette, N. Brassard, S. S. Iyer, M. Roger, L. Martin, M. Pazgier, J.-P. Routy, A. B. Smith, III, J. Park, D. M. Jones, J. R. Courter, B. N. Melillo, D. E. Kaufmann, B. H. Hahn, S. Permar, B. F. Haynes, N. Madani, J. Sodroski and A. Finzi. CD4 Mimetics Sensitize HIV-1-Infected Cells to ADCC. Proc. Natl. Acad. Sci. USA 2015, 112, E2687-E2694. PMC4443331. |
| 672. | A. B. Smith, III and J. R. Courter. The 2013 Benjamin Franklin Medal in Chemistry. J. Franklin. 2015, 352, 2603-2618. (Not NIH Funded). |
| 671. | A. Shvartsbart and A. B. Smith, III. The Daphniphyllum Alkaloids: Total Synthesis of (−)-Calyciphylline N. J. Am. Chem. Soc. 2015, 137, 3510-3519. |
| 670. | A. Sokolsky, X. Wang and A. B. Smith, III. Spirastrellolide E: Synthesis of an advanced C(1)-C(24) southern hemisphere. Tet. Lett. 2015, 56, 3160-3164. |
| 669. | M. Scotece, J. Conde, V. Abella, V. Lopez, J. Pino, F. Lago, A. B. Smith, III, J. J. Gómez-Reino and O. Gualillo. New Drugs from Ancient Natural Foods: Oleocanthal, the Naturally Occurring Spicy Compound of Olive Oil: a Brief History. Drug Discovery Today, 2015, 20, 406-410. (Not NIH Funded). |
| 668. | B. Li, B. D. Williams and A. B. Smith, III. A Mild, Diastereoselective Construction of Cyclic and Spirocyclic Ketals Employing a Tandem Photoisomerization/Cyclization Tactic. Org. Lett., 2015, 17, 3-5. PMC4295796. |
| 667. | A. B. Smith, III. Editorial 2015. Org. Lett., 2015, 17, 1-2. (Not NIH Funded). |
| 2014 | |
|---|---|
| 666. | B. D. Williams and A. B. Smith, III. Total Synthesis of (+)-18-epi-Latrunculol A: Development of a Synthetic Route. J. Org. Chem. 2014, 79, 9284-9296. |
| 665. | J. B. Munro, J. Gorman, X. Ma, J. Arthos, D. R. Burton, W. C. Koff, J. R. Courter, A. B. Smith, III, P. D. Kwong, S. C Blanchard and W. Mothes. Conformational Dynamics of Single HIV-1 Env Trimers on the Surface of Native Virions. Science 2014, 346, 759-763. PMC4304640. |
| 664. | X. Wang, L. Liu, L. Huang, K. Herbst-Robinson, A.-S. Cornec, M. James, S. Sugiyama, M. Bassetto, A. Brancale, J. Q. Trojanowski, V. M.-Y. Lee, A. B. Smith, III, K. R. Brunden and C. Ballatore. Potent, Long-Acting Cyclopentane-1,3-dione Thromboxane (A2)-Receptor Antagonists. ACS Med. Chem. Lett. 2014, 5, 1015-1020. PMC4160754. |
| 663. | C. Ballatore, B. Gay, L. Huang, K. H. Robinson, M. James, J. Q. Trojanowski, V. M.-Y. Lee, K. R. Brunden and A. B. Smith, III. Evaluation of the cyclopane-1,2-dione as a potential bio-isostere of the carboxylic acid functional group. Bioorg. Med. Chem. Lett. 2014, 24, 4175-4177. PMC4146692. |
| 662. | K. Lou, Y. Yao, A. Hoye, M. James, A.-S. Cornec, E. Hyde, B. Gay, V. M.-Y. Lee, J. Q. Trojanowski, A. B. Smith, III, K. R. Brunden and C. Ballatore. Brain-Penetrant, Orally Bioavailable Microtubule-Stabilizing Small Molecules as Potential Candidates for the Treatment of Alzheimer’s Disease and Related Tauopathies. J. Med. Chem. 2014, 47, 6116-6127. PMC4111403. |
| 661. | J. R. Courter, N. Madani, J. Sodroski, A. Schon, E. Freire, P. D. Kwong, W. A. Hendrickson, I. M. Chaiken, J. M. LaLonde and A. B. Smith, III. Structure-Based Design, Synthesis and Validation of CD4-Mimetic Small Molecule Inhibitors of HIV-1 Entry: Conversion of a Viral Entry Agonist to an Antagonist. Acc. Chem. Res. 2014, 47, 1228-1237. PMC3993944. |
| 660. | K. Vougogiannopoulou, C. Lemus, M. Halabalaki, C. Pergola, O. Werz, A. B. Smith, III, S. Michel, L. Skaltsounis and B. Deguin. One-Step Semisynthesis of Oleacein and its Identification as 5-lipoxygenase Inhibitor. J. Nat. Prod. 2014, 77, 441-445. (Not NIH Funded). |
| 659. | N. Madani, A. M. Princiotto, A. Schön, J. LaLonde, Y. Feng, E. Freire, J. Parks, J. Courter, D. Jones, J. Robinson, H.-X. Liao, M. A. Moody, S. Permar, B. Haynes, A. B. Smith, III, R. Wyatt and J. Sodroski. CD4-Mimetic Small Molecules Sensitize Human Immunodeficiency Virus (HIV-1) to Vaccine-Elicited Antibodies. J. Virol. 2014, 88, 6542-6555. |
| 658. | M. H. Nguyen and A. B. Smith, III. Recyclable Polystyrene-Supported Siloxane-Transfer Agent for Palladium-Catalyzed Cross-Coupling Reactions. Org. Lett. 2014, 16, 2070-2073. |
| 657. | K. R. Brunden, J. Q. Trojanowski, A. B. Smith, III, V. M.-Y. Lee and C. Ballatore. Microtubule-Stabilizing Agents as Potential Therapeutics for Neurodegenerative Disease. Bioorg. Med. Chem. 2014, 13, 01054-7. NIHMSID556452. |
| 656. | Y. D. Kwon, J. M. LaLonde, Y. Yang, M. A. Elban, A. Sugawara, J. R. Courter, D. M. Jones, A. B. Smith, III, A. K. Debnath and P.D. Kwong. Crystal Structures of HIV-1 gp120 Envelope Glycoprotein in Complex with NBD Analogues that Target the CD4 Binding Site. PLoS One. 2014, 9, e85940. PMC3904841. |
| 655. | M. Z. Chen, O. Gutierrez and A. B. Smith, III. Through-Bond/Through-Space Anion Relay Chemistry Exploiting Vinylepoxides as Bifunctional Linchpins. Angew. Chem. Int. Ed. 2014, 53, 1279-1282. |
| 654. | A. Shvartsbart and A. B. Smith, III. Total Synthesis of (−)-Calyciphylline N. J. Am. Chem. Soc. 2014, 136, 870-873. |
| 653. | J. R. Courter, M. Abdo, M. J. Tucker, S. P. Brown, R. M. Hochstrasser and A. B. Smith, III. The Design and Synthesis of Alanine-Rich α-Helical Peptides Constrained by an S,S-Tetrazine Photochemical Trigger: A Fragment Union Approach. J. Org. Chem. 2014, 79, 759-768. PMC3916828. |
| 652. | C. Ballatore, A. B. Smith, III, V. M.-Y. Lee, J. Q. Trojanowski and K. R. Brunden. Aminothienopyridazines as Imaging Probes of Tau Pathology: A Patent Evaluation of WO2013090497. Expert Opin Ther Pat. 2014, 24, 355-360. (Not NIH Funded). |
| 651. | A. B. Smith, III and J. Potuzak. The 2010 Benjamin Franklin Medal in Chemistry Presented to JoAnne Stubbe. J. Franklin Institute, 2014, 351, 1-11. |
| 650. | A. B. Smith, III. Organic Letters Update. Org. Lett. 2014, 16, 1-2. |
| 2013 | |
|---|---|
| 649. | M. H. Nguyen and A. B. Smith, III. Copper-Catalyzed Electrophillic Amination of Organolithium Compounds Mediated by Recoverable Siloxane Transfer Agents. Org. Lett. 2013, 15, 4872-4875. |
| 648. | D. G. Kuroda, M. Abdo, L. Chuntunov, A. B. Smith, III and R. M. Hochstrasser. Vibrational Dynamics of a Non-Degenerate Ultrafast Rotor: The (C12-C13)-Oxalate Ion. J. Chem. Phys. 2013, 139, 164514. PMC3829914. |
| 647. | B. D. Williams and A. B. Smith, III. Total Synthesis of (+)-18-epi-Latrunculol A. Org. Lett. 2013, 15, 4584-4587. |
| 646. | M. J. Tucker, M. Abdo, J. R. Courter, J. Chen, S. P. Brown, A. B. Smith, III and R. M. Hochstrasser. Non-Equilibrium Dynamics of Helix Reorganization Observed by Transient 2D IR Spectroscopy. PNAS 2013, 110, 17314-17319. PMC3808647. |
| 645. | M. H. Nguyen and A. B. Smith, III. Polymer-Supported Siloxane Transfer Agents for Pd-Catalyzed Cross-Coupling Reactions. Org. Lett. 2013, 15, 4258-4261. |
| 644. | T. Fricke, A. Brandariz-Nunez, X. Wang, A. B. Smith, III and F. Diaz-Griffero. Human Cytosolic Extracts Stabilize the HIV-1 Core. J. Virol. 2013, 87, 10587-10597. PMC3807412. |
| 643. | K. R. Brunden, M. J. James, Y. Yao, J. Q. Trojanowski, V. Y.-M. Lee, I. Paterson, C. Ballatore and A. B. Smith, III. MT-Stabilizer, Dictyostatin, Exhibits Prolonged Brain Retention: Potential Therapeutic Implications. ACS Med. Chem. Lett. 2013, 4, 886-889. |
| 642. | A. B. Smith, III. Editorial: Data Integrity. Org. Lett. 2013, 15, 2893-2894. (Not NIH Funded). |
| 641. | D. Martinez-Solorio, A. T. Hoye, M. H. Nguyen, and A. B. Smith, III. The Design, Synthesis and Validation of Recoverable and Readily Reusable Siloxane Transfer Agents for Pd-Catalyzed Cross-Coupling Reactions. Org. Lett. 2013, 15, 2454-2457. |
| 640. | B. Melillo and A. B. Smith, III. A Unified Synthetic Strategy to the Cryptocarya Family of Natural Products Exploiting Anion Relay Chemistry (ARC). Org. Lett. 2013, 15, 2282-2285. |
| 639. | C. An, J. A. Jurica, S. P. Walsh, A. T. Hoye and A. B. Smith, III. Total Synthesis of (+)-Irciniastatin A (aka Pysmberin) and (-)-Irciniastatin B. J. Org. Chem. 2013, 78, 4278-4296. |
| 638. | M. Scotece, R. Gómez, J. Conde, V. Lopez, J. J. Gómez-Reino, F. Lago, A. B. Smith, III and O. Gualillo. Oleocanthal inhibits proliferation and (MIP-1α) expression in human multiple myeloma cells. Curr. Med. Chem. 2013, 2467-2475. (Not NIH Funded). |
| 637. | D. J. Emerson, B. P. Weiser, J. Psonis, Z. Liao, O. Taratula, A. Fiamengo, X. Wang, K. Sugawara, A. B. Smith, III, R. G. Eckenhoff and I. Dmochowski. Direct Modulation of Microtubule Stability Contributes to Anthracene General Anesthesia. J. Am. Chem. Soc. 2013, 135, 5389-5398. |
| 636. | A. Crowe, M. James, V. M.-Y. Lee, A. B. Smith, III, J. Q. Trojanowski, C. Ballatore and K. R. Brunden. Aminothienopyridazines and Methylene Blue affect Tau Fibrillization via Cysteine Oxidation. J. Biol. Chem. 2013 288, 11024-11037. PMC3630889 |
| 635. | J. M. LaLonde, M. Le-Khac, D. M. Jones, J. R. Courter, J. Park, A. Schon, A. M. Princiotto, X. Wu, J. R. Mascola, E. Freire, J. Sodroski, N. Madani, W. A. Hendrickson and A. B. Smith, III. Structure-Based Optimization of a Small Molecule HIV-1 Entry Inhibitor Exploiting X-Ray and Thermodynamic Characterization. ACS Med. Chem. Lett. 2013, 4, 338-343. NIHMSID445081. |
| 634. | C. Ballatore, D. M. Huryn and A. B. Smith, III. Carboxylic Acid (Bio)-Isosteres in Drug Design. Chem. Med. Chem. 2013, 8, 385-395. NIHMSID455683. |
| 633. | G. L. Adams and A. B. Smith, III. Access to the Akuammiline Family of Alkaloids: Total Synthesis of (+)-Scholarisine A. J. Am. Chem. Soc. 2013, 135, 519-528. |
| 632. | A. B. Smith, III. Editorial. Org. Lett. 2013, 1, 1-2. |
| 2012 | |
|---|---|
| 631. | L. Sanchez and A. B. Smith, III. Long-Range Anion Relay Chemistry (LR-ARC): A Validated ARC Tactic. Org. Lett. 2012, 14, 6314-6317. |
| 630. | M. Scotece, R. Gómez, J. Conde, V. Lopez, J. J. Gómez-Reino, F. Lago, A. B. Smith, III and O. Gualillo. Further evidence for the anti-inflammatory activity of oleocanthal: Inhibition of MIP-1α and IL-6 in J774 macrophages and in ATDC5 chondrocytes. Life Sciences 2012, 91, 1229-1235 (Not NIH Funded). |
| 629. | Carlo Ballatore, Kurt R. Brunden, Donna M. Huryn, John Q. Trojanowski, Virginia M.-Y. Lee and Amos B. Smith, III. Microtubule Stabilizing Agents as a Potential Treatment for Alzheimer’s Disease and Related Neurodegenerative Tauopathies. J. Med. Chem. 2012, 55, 8979-8996. PMC3493881. |
| 628. | J. H. Soper, S. Sugiyama, K. Herbst-Robinson, M. James, X. Wang, J. Q. Trojanowski, A. B. Smith, III, V. M.-Y. Lee, C. Ballatore and K. R. Brunden. Brain-Penetrant Tetrahydronaphthalene Thromboxane A2-Prostanoid (TP) Receptor Antagonists as Prototype Therapeutics for Alzheimer’s Disease. ACS Chem. Neurosci. 2012 (ASAP). |
| 627. | A. Sokolsky and A. B. Smith, III. Validation of Diethoxy-phosphonate as an Effective Agent for Charge Transfer in Anion Relay Chemistry (ARC). Org. Lett. 2012, 14, 4470-4473. |
| 626. | C. An, A. T. Hoye and A. B. Smith, III. Total Synthesis of (−)-Irciniastatin B and Structural Confirmation via Chemical Conversion to (+)-Irciniastatin A (Psymberin). Org. Lett. 2012, 14, 4350-4353. |
| 625. | X. Wang, T. J. Paxton, N. Li and A. B. Smith, III. Spirastrellolide B: Construction of the C(26)-C(40) Northern Hemisphere and a Related [5,5,7]-Bis-Spiroketal Analogue. Org. Lett. 2012, 14, 3998-4001. |
| 624. | M. Abdo, S. Brown, J. Courter, M. Tucker, R. Hochstrasser and A. B. Smith, III. Design, Synthesis and Photochemical Validation of Peptide Linchpins Containing the S,S-Tetrazine Phototrigger. Org. Lett. 2012, 14, 3518-3521. PMC3397404. |
| 623. | S. Kortagere, N. Madani, M. K. Mankowski, A. Schön, I. Zentner, G. Swaminathan, A. Princiotto, K. Anthony, A. Oza, L.-J. Sierra, S. R. Passic, X. Wang, D. M. Jones, E. Stavale, F. C. Krebs, J. Martínez-García, E. Freire, R. G. Ptak, J. Sodroski, S. Cocklin and A. B. Smith, III. Inhibiting Early-Stage Events in HIV-1 Replication by Small-Molecule Targeting of the HIV-1 Capsid. J. Virol. 2012, 86, 8472-8481. Not NIH Funded. |
| 622. | C. Ballatore, A. Crowe, F. Piscitelli, M. James, K. Lou, G. Rossidivito, J. Q. Trojanowski, V. M.-Y. Lee, K. R. Brunden and A. B. Smith, III. Aminothienopyridazine Inhibitors of Tau Aggregation: Evaluation of Structure-Activity Relationships Leads to Selection of Candidates with Desirable In Vivo Properties. Bioorg. Med. Chem. 2012, 20, 4451-4461. (Not NIH Funded). |
| 621. | K. R. Brunden, C. Ballatore, V. M.-Y. Lee, A. B. Smith, III and J. Q. Trojanowski. Brain-Penetrant Microtubule Stabilizing Compounds as Potential Therapeutic Agent for Tauopathies. Biochem. Soc. Trans. 2012, 40, 661-666. NIHMS396940. PMC Journal – In Process. |
| 620. | J. M. LaLonde, Y. D. Kwon, D. M. Jones, A. W. Sun, J. R. Courter, T. Soeta, T. Kobayashi, A. M. Princiotto, X. Wu, J. Mascola, A. Schon, E. Freire, P. D. Kwong, J. Sodroski, N. Madani and A. B. Smith, III. Structure-Based Design, Synthesis and Characterization of Dual Hot Spot Small-Molecule HIV-1 Entry Inhibitors. J. Med. Chem. 2012, 55, 4382-4396. PMC3376652. |
| 619. | M. J. Tucker, M. Abdo, J. R. Courter, J. Chen, A. B. Smith, III and R. M. Hochstrasser. Di-Cysteine S,S-Tetrazine: A Potential Ultra-fast Photochemical Trigger to Explore the Early Events of Peptide/Protein Folding. J. Photochem. Photobiol. A. 2012, 234, 156-163. PMC3345895. |
| 618. | B. Zhang, J. Carroll, J. Q. Trojanowski, Y. Yao, M. Iba, J. S. Potuzak, A.-M. L. Hogan, S. Xie, C. Ballatore, A. B. Smith, III, V. M.-Y. Lee and K. R. Brunden. Microtubule-Stabilizing Agent, Epothilone D, Reduces Axonal Dysfunction, Cognitive Deficits, Neurotoxicity and Alzheimer-like Pathology in an Interventional Study With Aged Tau Transgenic Mice. J. Neurosci. 2012 32 3601-3611. PMC3321513. |
| 617. | A. B. Smith, III, A. T. Hoye, D. Martinez-Solorio, W.-S. Kim and R. Tong. Unification of Anion Relay Chemistry (ARC) with the Takeda and Hiyama Cross-Coupling Reactions: Identification of an Effective Silicon-Based Transfer Agent. J. Am. Chem. Soc. 2012 134, 4533–4536. |
| 616. | G. L. Adams, P. J. Carroll and A. B. Smith, III. Total Synthesis of (+)-Scholarisine A. J. Am. Chem. Soc. 2012 134, 4037-4040. |
| 615. | A. B. Smith, III. Editorial: Organic Letters: Now in the 21st Century. Org. Lett. 2012, 1-2. |
| 2011 | |
|---|---|
| 614. | C. Ballatore, J. Soper, F. Piscitelli, M. James, L. Huang, O. Atasoylu, D. Huryn, J. Q. Trojanowski, V. M.-Y. Lee, K. R. Brunden and A. B. Smith, III. Cyclopentane-1,3-dione: a novel isostere for the carboxylic acid functional group. Application to the design of potent thromboxane (A2) receptor antagonists. J. Med. Chem. 2011, 54, 6969-6983. PMC3188681. |
| 613. | A. Herschhorn, A. Finzi, D. Jones, J. R. Courter, A. Sugawara, A. B. Smith, III and J. Sodroski. An Inducible Cell-cell Fusion System with Integrated Ability to Measure the Efficiency and Specificity of HIV-1 Entry Inhibitors. PLoS 2011, 6, e26731. |
| 612. | A. B. Smith, III, S. Dong, R. J. Fox, J. B. Brenneman, J. A. Vanecko and T. Maegawa. (+)-Sorangicin A; Evolution of a Viable Synthetic Strategy. Tetrahedron 2011, 67, 9809-9828. |
| 611. | Q. Xu, K.-C. Huang, K. TenDyke, J. Marsha, J. Liu, D. Qiu, B. Littlefield, K. Nomoto, O. Atasoylu, C. A. Risatti, J. B. Sperry and A. B. Smith, III. In Vitro and In Vivo Anti-Cancer Activity of (+)-Spongistatin 1. Anticancer Res. 2011, 31, 2773-2779. PMC3181053. |
| 610. | A. B. Smith, III, O. Atasoylu, K. Sugawara, S. Horwitz. Design and Synthesis of (+)-Discodermolide-Paclitaxel Hybrids Leading to Enhanced Biological Activity. J. Med. Chem. 2011, 54, 6319-6327. |
| 609. | A. B. Smith, III, C. Risatti, O. Atasoylu, C. S. Bennett, J. Liu, H. Cheng, K. TenDyke, Q. Xu. Design, Synthesis and Biological Evaluation of Diminutive Forms of (+)-Spongistatin I: Lessons Learned. J. Am. Chem. Soc. 2011, 133, 14042-14053. |
| 608. | A. B. Smith, III, R. Tong, W.-S. Kim and W. A. Maio. Anion Relay Chemistry: Access to the Type II Reaction Manifold via a Fundamental Different Reaction Pathway Exploiting 1-Oxa-2-Silacyclopentanes and Related Congeners. Angew. Chem. Int. Ed. 2011, 50, 8904-8907. |
| 607. | R. Bai, T. L. Nguyen, J. C. Burnett, O. Atasoylu, M. G. H. Munro, G. R. Pettit, A. B. Smith, III, R. Gussio, and E. Hamel. Interactions of Halichondrin B and Eribulin With Tubulin. J. Chem. Inf. Model 2011, 51, 1393-140. PMC3130535. |
| 606. | H. Haim, B. Strack, A. Kassa, N. Madani, L. Wang. J. Courter, A. Princiotto, K. McGee, B. Pacheco, M. S. Seeman, A. B. Smith, III and J. Sodroski. Contribution of Intrinsic Reactivity of the HIV-1 Envelope Glycoprotein to CD4-Independent Infection and Global Inhibitor Sensitivity. PLoS Pathogen 2011, 7, e1002101. PMC3121797. |
| 605. | A. B. Smith, III, H. Han and W.-S. Kim. Diversity-Oriented Synthesis of 2,4,6-trisubstituted Piperidines via Type II Anion Relay Chemistry (ARC). Org. Lett. 2011, 13, 3328-3331. |
| 604. | J. A. Gladding, J. P. Bacci, S. A. Shaw, A. B. Smith, III. Sporolide B: Synthetic Studies. Tetrahedron 2011, 67, 6697-6706. PMC3197724. |
| 603. | S. A. Kuriakose, I. J. Zentner, A. Schön, K. McFadden, M. Umashankara, S. Rajagopal, M. Contarino, C. Duffy, J. Courter, D. Jones, M.-Y. Zhang, J. M. Gershoni, S. Cocklin, D. S. Dimitrov, A. B. Smith, III, E. Freire, I. M. Chaiken. Conformational and Structural Features of HIV-1 gp120 Underlying its Dual Antagonism by the Cross-Reactive Neutralizing Antibody, m18. Biochemistry 2011, 50, 2756-2768. PMC3088361. |
| 602. | A. B. Smith, III, A.-M. Hogan, Z. Liu, T. M. Razler, R. M. Meis, B. I. Morinaka and T. F. Molinski. Phorboxazole Synthetic Studies: Design, Synthesis and Biological Evaluation of Phorboxazole A and Hemi-Phorboxazole A Related Analogues. Tetrahedron 2011, 67, 5069-5078. PMC3146768 |
| 601. | A. B. Smith, III and W.-S. Kim. Diversity Oriented Synthesis Leads to a New Class of Bi-functional Linchpins Uniting Anion Relay Chemistry (ARC) with Benzyne Reactivity. Proc. Nat. Acad. Sci. 2011, 108, 6787-6792. PMC3084103. |
| 600. | A. B. Smith, III, A. K. Charnley and R. Hirschmann. Pyrrolinone-Based Peptidomimetics. “Let the Enzyme or Receptor be the Judge”. Acc. Chem. Res. 2011, 44, 180-193. |
| 599. | A. B. Smith, III, N. Kutsumura and J. Potuzak. A Formal Total Synthesis of (⎯)-Brevisamide. Tet. Lett. 2011, 52, 2117-2119. PMC3092486. |
| 598. | K. R. Brunden, Y. Yao, J. Potuzak, N. I. Ferrer, C. Ballatore, M. James, A.-M. L. Hogan, J. Q. Trojanowski, A. B. Smith, III and V. M.-Y. Lee. The Characterization of Microtubule-Stabilizing Drugs as Possible Therapeutic Agents for Alzheimer’s Disease and Related Tauopathies. Pharmacological Research. 2011, 63, 341-351. PMC3042036. |
| 597. | S. K. Chao, J. Lin, J. Brouwer-Visser, A. B. Smith, III, S. B. Horwitz, and H. M. McDaid. Resistance to Discodermolide, a Microtubule Stabilizing Agent and Senescence Inducer, is 4E-BP1 Dependent. Proc. Nat Acad. Sci. 2011, 108, 391-396. PMC3017154. |
| 596. | A. Schön, N. Madani, A. B. Smith, III, J. M. LaLonde and E. Freire. Some Binding-RelatedDrug Properties are Dependent on Thermodynamic Signature. Chem. Biol. Drug Des. 2011, 77, 161-165. PMC3079564. |
| 595. | J. M. LaLonde, M. Elban, J. Courter, A. Sugawara, T. Soeta, N. Madani, A. M. Princiotto, Y. D. Kwon, P. D. Kwong, A. Schön, E. Freire, J. Sodroski and A. B. Smith, III. Design, Synthesis and biological evaluation of small molecule inhibitors of CD4-gp120 binding based on virtual screening. Bioorg. Med. Chem. 2011, 19, 91-101. PMC3049263. |
| 594. | C. P. des Gachons, K. Uchida, B. Bryant, A. Shima, J. B. Sperry, L. Dankulich-Nagrudny, M. Tominaga, A. B. Smith, III, G. K. Beauchamp and P. A. S. Breslin. Unusual pungency from extra-virgin olive oil is due to restricted spatial expression of oleocanthal’s receptor. J. Neurosci. 2011, 31, 999-1009. PMC3073417. |
| 593. | C. Ballatore, K. R. Brunden, J. Q. Trojanowski, V. M-Y. Lee, A. B. Smith, III and D. Huryn. Modulation of Protein-Protein Interactions as a Therapeutic Strategy for the Treatment of Neurodegenerative Tauopathies. Curr. Top. Med. Chem. 2011, 11, 317-330. PMC3069499 |
| 592. | A. B. Smith, III and H, Xiong. The 2008 Benjamin Franklin Medal in Chemistry is Presented to Albert Eschenmoser, Dr. sc.nat. J. Franklin I. 2011, 348, 481-488. (Not NIH Funded) |
| 2010 | |
|---|---|
| 591. | J. D. Clifton, M. C. Myers, A. B. Smith, III, E. Lucumi, A. Napper, D. M. Huryn, S. L. Diamond, and M. Pack. Identification of Novel Inhibitors of Dietary Lipid Absorption Using Zebrafish. PLos One 2010, 5, e12386. PMC2928291. |
| 590. | K. R. Brunden, B. Zhang, J. Carroll, Y. Yao, J. S. Potuzak, A.-M. Hogan, M. Iba, M. J. James, S. X. Xie, C. Ballatore, A. B. Smith, III, V. M.-Y. Lee, and J. Q. Trojanowski. Epothilone D Improves Microtubule Density, Axonal Integrity and Cognition in a Transgenic Mouse Model of Tauopathy. J. Neurosci. 2010, 30, 13861-13866. PMC2958430. |
| 589. | A. B. Smith, III, T. Lewandowski. Editorial: The NIH Public Access Mandate. Org. Lett. 2010, 12, 3967. |
| 588. | P. P. Shah, T. Wang, R. L. Kaletsky, M. C. Myers, J. E. Purvis, H. Jing, D. M. Huryn, D. G. Greenbaum, A. B. Smith, III and S. L. Diamond. A small-molecule oxocarbazate inhibitor of human cathepsin L blocks severe acute respiratory syndrome and ebola pseudotype virus infection into human embryonic kidney 293T cells. Mol. Pharma. 2010, 78, 319-324. PMC2917856. |
| 587. | A. Iacono, R. Gómez, J. Sperry, J. Conde, G. Bianco, R. Meli, A. B. Smith, III and O. Gualillo. Effect of oleocanthal and its derivatives on inflammatory response induced by LPS in chondrocyte cell line. Arthritis Rheum. 2010, 62, 1675-1682. PMID20201078 (Not NIH Funded). |
| 586. | A. B. Smith, III, H. Smits and D.-S. Kim. Spirastrellolide Studies. Synthesis of the C(1)-C(25) Southern Hemisphere of Spirastrellolides A and B, Exploiting Anion Relay Chemistry. Tetrahedron 2010, 66, 6597-6605. PMC2915457. |
| 585. | C. Ballatore, K. R. Brunden, F. Piscitelli, M. James, A. Crowe, M. Yao, J. Q. Trojanowski, V. M.-Y. Lee and A. B. Smith, III. Discovery of a Brain-Penetrant and Orally Bioavailable Aminothienopyridazine Inhibitor of Tau Aggregation. J. Med. Chem. 2010, 53, 3739-3747. PMC2872922. |
| 584. | M. J. Tucker, J. R. Courter, J. Chen, A. B. Smith, III and R. M. Hochstrasser. Tetrazine phototriggers: Probes for protein dynamics. Angew. Chem. Int. Ed. 2010, 49, 3612-3616. PMC2903731. |
| 583. | A. B. Smith, III, H. Xiong, A. K. Charnley, M. Brenner, E. F. Mesaros, C. S. Kenesky, L. di Costanzo, D. Christianson and R. Hirschmann. Design, Synthesis and Structural Analysis of D, L-Mixed Polypyrrolinones 2: Macrocyclic Hexapyrrolinones. Org. Lett. 2010, 12, 2994-2997. PMC2892552. |
| 582. | A. B. Smith, III, W. Wang, A. K. Charnley, P. J. Carroll, C. S. Kenesky and R. Hirschmann. Design, Synthesis and Structural Analysis of D,L-Mized Polypyrrolinones 1: From Nonpeptide Peptidomimetics to Nanotubes. Org. Lett. 2010, 12, 2990-2993. PMC2892756. |
| 581. | A. B. Smith, III, C. A. Risatti, O. Atasoylu, C. S. Bennett, K. TenDyke and Q. Xu. Design, Synthesis and Biological Evaluation of EF- and ABEF- Analogs of (+)-Spongistatin 1. Org. Lett. 2010, 12, 1792-1795. PMC2853872. |
| 580. | O. Atasoylu, G. Furst, C. Risatti and A. B. Smith, III. The Solution Structure of (+)-Spongistatin 1 in DMSO. Org. Lett. 2010, 12, 1788-1791. PMC2856070. |
| 579. | H.-S. Lee, M. Contarino, M. Umashankara, A. Schoen, E. Freire, A. B. Smith, III, I. M. Chaiken, M. Irwin and L. S. Penn. Use of the quartz crystal microbalance to monitor ligand-induced conformational rearrangements in HIV-1 envelope protein gp120. Anal. Bioanal. Chem. 2010, 396, 1143-1152. PMC2903444. |
| 578. | Z. Liu, M. C. Myers, P. P. Shah, M. P. Beavers, P. A. Benedetti, S. L. Diamond, A. B. Smith, III, and D.M. Huryn. Design, Synthesis and Biological Evaluation of a Library of Thiocarbazates and Their Activity as Cysteine Protease Inhibitors. Comb. Chem. High Throughput Screening. 2010, 337-351. PMC2975254. |
| 577. | K. R. Brunden, C. Ballatore, A. Crowe, A. B. Smith, III, V. M.-Y. Lee and J. Trojanowski. Tau-Directed Drug Discovery for Alzheimer’s Disease and Related Taupathies: A Focus on Tau Assembly Inhibitors. Experimental Neurology 2010, 223, 304-310. PMC2864354 |
| 576. | A. B. Smith, III and R. Tong. Benzyl and Phenylthiomethyl Silanes: A New Class of Bifunctional Linchpins for Type II Anion Relay Chemistry (ARC). Org. Lett. 2010, 12, 1260-1263. PMC2844645 |
| 575. | A. B. Smith, III, W.-S. Kim and R. Tong. Uniting Anion Relay Chemistry with Pd-Mediated Cross Coupling: Design and Evaluation of Bifunctional Aryl and Vinyl Silane Linchpins. Org. Lett. 2010, 12, 588-591. PMC2813984 |
| 574. | J. B. Sperry; A. B. Smith, III “Synthesis of Diverse Phenolic Compounds Isolated From Olive Oils”, in Olives and Olive Oil in Health and Disease Prevention; V.R. Preedy; R.R. Watson, eds; Academic Press, London, 2010, pp. 1439-1464. |
| 2009 | |
|---|---|
| 573. | A. Kassa, N. Madani, A. Schön, H. Haim, A. Finzi, S. Xiang, L. Wang, A. Princiotto, M. Pancera, J. Courter, E. Freire, P.D. Kwong, A.B. Smith, III and J. Sodroski. Transitions to and from the CD4-bound Conformation are Modulated by a Single-Residue Change in the HIV-1 gp120 Inner Domain. J. Virol. 2009, 83, 8364-8378. PMC2738180. |
| 572. | M. Khrapunovich-Baine, V. Menon, P. Verdier-Pinard, A. B. Smith, III, R. Angeletti, A. Fiser, S. B. Horwitz and H. Xiao. Distinct Orientation of Discodermolide in Taxol Binding Pocket Drives a Complementary Mode of Microtubule Stabilization. Biochemistry. 2009, 48, 11664-11677. PMC2845443. |
| 571. | F. Piscitelli, C. Ballatore and A. B. Smith, III. Solid-Phase Synthesis of 2-Aminobenzothiazoles. Bioorg. Med. Chem. Lett. 2009, 20, 644-648. PMC2818510. |
| 570. | D. M. Huryn and A. B. Smith, III. The Identification, Characterization and Optimization of Small Molecule Probles of Cysteine Proteases: Experiences of the Penn Center for Molecular Discovery with Cathepsin B and Cathepsin L. Curr. Top. Med. Chem., 2009, 9, 1206-1216. PMC2909000. |
| 569. | J. Pitt, W. Roth, P. Lacor, A. B. Smith, III, M. Blankenship, P. Velasco, F. DeFelice, P. Breslin and W. L. Klein. Alzheimer’s-associated Aβ oligomers show altered structure, immunoreactivity and synaptotoxicity with low doses of oleocanthal. Toxicology and Applied Pharmacology, 2009, 240, 189-197. PMC2808212 |
| 568. | A. B. Smith, III. “Ralph F. Hirschmann, May 6, 1922-June 20, 2009.” Organic Reactions 2009, IX-XI. |
| 567. | A. B. Smith, III, Z. Liu, and V. Simov. An Efficient Protocol for the Oxidative Hydrolysis of Ketone SAMP Hydrazones Employing SeO2 and H2O2 Under Buffered (pH7) Conditions. Syn. Lett. 2009, 19, 3131-3134. PMC2909127. |
| 566. | R. F. Hirschmann, K. C. Nicolaou, A. R. Angeles, J. S. Chen, and A. B. Smith, III. The β-D-Glucose Scaffold as a β-Turn Mimetic. Acc. Chem. Res. 2009, 42, 1511-1520. |
| 565. | A. B. Smith, III, Z. Liu, A.-M. L. Hogan, D. S. Dalisay and T. F. Molinski. Hemi-Phorboxazole A: Structure Confirmation, Analogue Design and Biological Evaluation. Org. Lett. 2009, 11, 3766-3769. PMC2743491. |
| 564. | A. B. Smith, III, O. Atasoylu and D. C. Beshore. Construction of 5,6-Fused 2-Pyridones: An Effective Annulation Tactic Achieved in Water. Syn. Lett. 2009, 16, 2643-2646. PMC2904244. |
| 563. | A. B. Smith, III, S. Dong, J. B. Brenneman and R. J. Fox. Total Synthesis of (+)-Sorangicin A. J. Am. Chem. Soc., 2009, 131, 12109-12111. PMC2749982. |
| 562. | A. B. Smith, III, M. A. Foley, S. Dong, and A. Orbin. (+)-Rimocidin Synthetic Studies: Construction of the C(1-27) Aglycone Skeleton. J. Org. Chem., 2009, 74, 5987-6001. PMC2891182. |
| 561. | A. B. Smith, III, C. Sfouggatakis, C. A. Risatti, J. B. Sperry, W. Zhu, V. A. Doughty, T. Tomioka, D. B. Gotchev, C. S. Bennett, S. Sakamoto, O. Atasoylu, S. Shirakami, D. Bauer, M. Takeuchi, J. Koyanagi and Y. Sakamoto. Spongipyran Synthetic Studies. Evolution of a Scalable Total Synthesis of (+)-Spongistatin 1. Tetrahedron, 2009, 65, 6489-6509. PMC2902791. |
| 560. | A. B. Smith, III, Q. Lin, V. A. Dougherty, L. Zhuang, M. D. McBriar, J. K. Kerns, A. M. Boldi, N. Murase, W. H. Moser, C. S. Brook, C. S. Bennett, K. Nakayama, M. Sobukawa and R. E. L. Trout. Spongipyran Synthetic Studies. Total Synthesis of (+)-Spongistatin 2. Tetrahedron, 2009, 65, 6470-6488. PMC2712115. |
| 559. | A. Crowe, W. Huang, C. Ballatore, R. Johnson, A. M. Hogan, R. Huang, J. Wichtermann, J. McCoy, D. Huryn, D. Auld, A. B. Smith, III, J. Inglese, J. Trojanowski, C. Austin, K. R. Brunden and V. M.-Y. Lee. The Identification of Aminothienopyridazine Inhibitors of Tau Assembly by Quantitative High-Throughput Screening. Biochemistry, 2009, 48, 7732-7745. PMC2773749. |
| 558. | S. Bagchi, A. K. Charnley, A. B. Smith, III and R. M. Hochstrasser. Equilibrium exchange processes of the aqueous Tryptophan dipeptide. J. Phys. Chem. B. 2009, 113, 8412-8417. PMC2929808. |
| 557. | W. Li, J. Sperry, A. Crowe, I. V. J. Murphy, P. H. Axelsen, A. B. Smith, III, J. Q. Trojanowski, V. M. Y. Lee. Inhibition of Tau Fibrillization by Oleocanthal via Reaction with the Amino Groups of Tau. J. Neurochem. 2009, 110, 1339-1351. PMC2758489. |
| 556. | A. Kassa, A. Finzi, M. Pancera, J. Courter, A.B. Smith, III and J. Sodroski. Identification of a Human Immunodeficiency Virus (HIV-1) Envelope Glycoprotein Variant Resistant to Cold Inactivation. J. Virol. 2009, 83, 4476-4488. PMC2668461. |
| 555. | H. Haim, Z. Si, N. Madani, L. Wang, J.R. Courter, A. Princiotto, A. Kassa, M. DeGrace, K. McGee-Estrada, M. Mefford, D. Gabuzda, A.B. Smith, III and J. Sodroski. Soluble CD4 and CD4-mimetic compounds inhibit HIV-1 infection by induction of a short-lived activated state. PLoS Pathogens. USA. 2009, 5(4): e1000360. PMC2655723. |
| 554. | N. O. Devarie-Baez, W. Kim, A. B. Smith, III and M. Xian. Multicomponent Type II Anion Relay Chemistry (ARC): “One-Pot” Syntheses of 2,3-Disubstituted Furans and Thiophenes. Org. Lett. 2009, 11, 1861-1864. PMC2777545. |
| 553. | A. B. Smith, III, T. Bosanac, and K. Basu. Evolution of the Total Synthesis of (−)-Okilactomycin Exploiting a Tandem Oxy-Cope Rearrangement/Oxidation, a Petasis-Ferrier Union/Rearrangement, and Ring-Closing Metathesis. J. Am. Chem. Soc. 2009, 131, 2348-2358. PMC2697663. |
| 552. | A. B. Smith, III, S. Dong. An Efficient, Second-Generation Synthesis of the Signature Dioxabicyclo [3.2.1]octane Core of (+)-Sorangicin A and Elaboration of the Z,Z,E-Triene Acid System. Org. Lett. 2009, 11, 1099-1102. PMC2880660. |
| 2008 | |
|---|---|
| 551. | N. Madani, A. Schon, A. M. Princiotto, J. LaLonde, J. Courter, T. Soeta, D. Ng, L. Wang, E. Brower, S. Xiang, R. Wyatt, P. D. Kwong, E. Freire, A. B. Smith, III, and J. Sodroski. Small-Molecule CD4 Mimics Interact with a Highly Conserved Pocket on the HIV-1 gp120. Structure 2008, 16, 1689-1701. PMC2597202. |
| 550. | Smith, A. B., III, Jurica, J. A., and Walsh, S. P. Total Synthesis of (+)-Psymberin (a.k.a. Irciniastatin A): Catalytic Reagent Control as the Strategic Cornerstone. Org. Lett. 2008, 10, 5625-5628. PMC2750869. |
| 549. | C. Ballatore, B. Zhang, J. Q. Trojanowski, V. M.-Y. Lee, and A. B. Smith, III. In Situ Blood-Brain Barrier Permeability of a C-10 Paclitaxel Carbamate. Bioorg. Med. Chem. Lett. 2008, 18, 6119-6121. PMC2603177. |
| 548. | A. B. Smith, III, J. M. Cox, N. Furuichi, C. S. Kenesky, J. Zheng, and W. Wuest. Total Synthesis of (−)-2-Epi-Peloruside A. Org. Lett. 2008 10 (24), 5501-5504. PMC2697658. |
| 547. | A. B. Smith, III and W. M. Wuest. Evolution of Multi-Component Anion Relay Chemistry (ARC): Construction of Architecturally Complex Natural and Unnatural Products. Chem. Comm. 2008, 5883-5895. PMC2769507. |
| 546. | D. C. Beshore and A. B. Smith, III. The Lyconadins: Enantioselective Total Synthesis of (+)-Lyconadin A and (−)-Lyconadin B. J. Am. Chem. Soc. 2008, 130, 13778-13789. PMC2819465. |
| 545. | A. B. Smith, III, and Z. Liu. Total Synthesis of (−)-Aplaminal. Org. Lett. 2008, 10, 4363-4365. PMC2775134. |
| 544. | A. B. Smith, III, W. S. Kim and W. M. Wuest. Ortho-TMS Benzaldehyde: An Effective Linchpin for Type II Anion Relay Chemistry. Angew. Chem. Int. Ed. 2008, 47, 7082-7086. PMC2756143. |
| 543. | A. B. Smith, III, T. Tomioka, C. A. Risatti, J. B. Sperry, and C. Sfouggatakis. Gram-Scale Synthesis of (+)-Spongistatin 1. An Improved, Scalable Synthesis of the F-Ring Subunit, Fragment Union, and Final Elaboration. Org. Lett. 2008, 10, 4359-4362. PMC2819470. |
| 542. | H. Gopi, M. Umashankara, V. Pirrone, J. LaLonde, N. Madani, F. Tuzer, S. Baxter, I. Zentner, S. Cocklin, N. Jawanda, S. R. Miller, A. Schön, J. C. Kelin, E. Freire, F. C. Krebs, A. B. Smith, III, J. Sodroski and I. Chaiken. Structural Determinants for Affinity Enhancement of a Dual Antagonist Peptide Entry Inhibitor of Human Immunodeficiency Virus Type-1. J. Med. Chem. 2008, 51, 2638-2647. PMC2921370. |
| 541. | M. P. Beavers, M. C. Myers, P. P. Shah, J. E. Purvis, S. L. Diamond, B. S. Cooperman, D. M. Huryn, and A. B. Smith, III. Molecular Docking of Cathepsin L Inhibitors in the Binding Site of Papain. J. Chem. Inf. Model 2008, 48, 1464-1472. PMC2923042. |
| 540. | M. Myers, P. P. Shah, M. P. Beavers, S. L. Diamond, A. B. Smith, III, and D. M. Huryn. The Design, Synthesis and Evaluation of Inhibitors of Cathepsin L: Exploiting a Unique Thiocarbazate Chemotype. Bioorg. Med. Chem. Lett. 2008, 18, 3646-3657. PMC2494853. |
| 539. | P. P. Shah, M. C. Myers, M. P. Beavers, J. E. Purvis, D. M. Huryn, A. B. Smith, III, and S. L. Diamond. Kinetic Characterization and Molecular Docking of a Novel, Potent, and Selective Slow-Binding Inhibitor of Human Cathepsin L. Mol. Pharmacol. 2008, 74, 34-41. PMC2575030. |
| 538. | A. B. Smith, III, R. J. Fox, and T. M. Razler. Evolution of the Petasis-Ferrier Union/Rearrangement Tactic: Construction of Architecturally Complex Natural Products Possessing the Ubiquitous cis-2,6-Substituted Tetrahydropyran Structural Element. Acc. Chem. Res. 2008, 41, 675-687. |
| 537. | A. B. Smith, III, T. M. Razler, J. P. Ciavarri, T. Hirose, T. Ishikawa, and R. M. Meis. Synthesis and Biological Evolution of Phorboxazole Congeners Leading to the Discovery and Preparative-Scale Synthesis of (+)- Chlorophorboxazole A Possessing Picomolar Tumor Cell Growth Inhibatory Activity. J. Org. Chem. 2008, 73, 1201-1208 |
| 536. | A. B. Smith, III, T. M. Razler, J. P. Ciavarri, T. Hirose, T. Ishikawa, and R. M. Meis. A Second-Generation Total Synthesis of (+)- Phorboxazole A. J. Org. Chem. 2008, 73, 1192-1200. |
| 535. | A. B. Smith, III, M. O. Duffey, K. Basu, S. P. Walsh, and M. Frohn. Total Synthesis of the Assigned Structure of Lituarine B and C. J. Am. Chem. Soc. 2008, 130, 422-423. |
| 534. | A. B. Smith, III and B. S. Freeze. (+)-Discodermolide: Total Syntheses, Construction of Novel Analogues, and Biological Evaluation: An Overview. Tetrahedron, 2008, 64, 261-298. PMC2991168. |
| 533. | M. Myers, P. P. Shah, S. L. Diamond, D. M. Huryn, and A. B. Smith, III. Identification and Synthesis of a Unique Thiocarbazate Cathepsin L Inhibitor. Bioorg. Med. Chem. Lett. 2008,18, 210-214. PMCID2423727 |
| 532. | A. B. Smith, III. Editorial 2008, Org. Lett. 2008,10, 1-3. |
| 2007 | |
|---|---|
| 531. | A. B. Smith, III, K. Basu, T. Bosanac. Total Synthesis of (−)-Okilactomycin. J. Am. Chem. Soc. 2007, 129, 14872-14874. |
| 530. | H. Xie, D. Ng, S. Savinov, B. Dey, P. D. Kwong, R. Wyatt, A. B. Smith, III, and W. A. Hendrickson. Structure-activity Relationship in the Binding of Chemically Derivatized CD4 to HIV gp120. J. Med. Chem. 2007, 50, 4898-4908. |
| 529. | S. Shaw, H. Menzella, D. C. Miller, M. Xian and A. B. Smith, III. Coumarin-derived discodermolide analogues with equivalent potency as the Natural Product—a further simplification of the lactone region. Org. Biomol. Chem. 2007, 5, 2753-2755. |
| 528. | A. B. Smith, III and D. Lee. Total Synthesis of (+)- Tedanolide. J. Am. Chem. Soc. 2007, 129, 10957-10962. |
| 527. | A. B. Smith, III, J. B. Sperry and Q. Han. Synthesis of (−)-Oleocanthal, a Natural NSAID Found in Extra Virgin Olive Oil, (−)-Deacetoxy-oleuropein Aglycone and Related Analogies. J. Org. Chem. 2007, 72, 6891-6900. |
| 526. | M. C. Myers, A. D. Napper, N. Motlekar, P. P. Shah, C. Chiu, M. P. Beavers, S. L. Diamond, D. M. Huryn, and A. B. Smith, III. Identification and Characterization of 3-Substituted Pyrazolyl Esters as Alternative Substrates for Cathepsin B. The Confounding Effects of DTT and Cysteine in Biological Assays. Bioorg. Med. Chem. Lett. 2007, 17, 4761-4766. |
| 525. | A. B. Smith, III and D. S. Kim. The Spirastrellolides: Construction of the Southern C(1)-C(25) Fragment Exploiting Anion Relay Chemistry. Org. Lett. 2007, 9, 3311-3314. |
| 524. | A. B. Smith, III, D. S. Kim, and M. Xian. Anion Relay Chemistry Extended. Synthesis of a Gorgonian Sesquiterpene. Org. Lett. 2007, 9, 3307-3309. |
| 523. | C. Ballatore, E. Hyde, R. Deicher, V. Lee, J.Q. Trojanowski, D. Huryn, and A. B. Smith, III. Paclitaxel C10 carbamates: potential candidates for the treatment of neurodegenerative tauopathies. Bioorg. Med Chem Lett. 2007, 17, 3642-3646. |
| 522. | A. B. Smith, III, L. Kürti, A. H. Davulcu, Y.-S. Cho, H. Ishiyama, and K. Ohmoto. Indole Diterpene Synthetic Studies: Development of a Second Generation Synthetic Strategy for (+)-Nodulipsoric Acids A and B. J. Org. Chem. 2007, 72, 4611-4620. |
| 521. | A. B. Smith, III, L. Kürti, A. H. Davulcu, Y.-S. Cho, H. Ishiyama, and K. Ohmoto. Indole Diterpene Synthetic Studies: Total Synthesis of (+)-Nodulisporic Acid F and Construction of the Heptacyclic Cores of (+)-Nodulisporic Acis A and B and (–)-Nodulisporic Acid D. J. Org. Chem. 2007, 72, 4596-4610. |
| 520. | S. Bagchi, Y.S. Kim, A.K. Charnley, A. B. Smith, III, and R. M. Hochstrasser. Two-Dimensional Infrared Investigation of N-Acetyl Tryptophan Methyl Amide in Solution. J. Phys. Chem. B. 2007, 111, 3010-3018. |
| 519. | D. C. Beshore and A. B. Smith, III. Total Synthesis of (+)-Lyconadin A and (−)-Lyconadin B. J. Am. Chem. Soc. 2007, 129, 4148-4149. |
| 518. | A. B. Smith, III, L. Kürti, and A. H. Davulcu. Development of a Scalable Synthesis of a Common Eastern Tricyclic Lactone for Construction of the Nodulisporic Acids. Org. Proc. Res. Dev. 2007, 11 (1) 19-24. |
| 2006 | |
|---|---|
| 517. | B. P. Mowery, V. Prasad, C. S. Kenesky, A. R. Angeles, L. L. Taylor, J.-J. Feng, W.-L. Chen, A. Lin, F.-C. Cheng, A. B. Smith, III, and R. Hirschmann. Catechol: A Minimal Scaffold for Non-Peptide Mimetics of the i+1 and i+2 Positions of β-turns. Application to Somatostatin. Org. Lett. 2006, 8, 4397-4400. |
| 516. | S. Xian, C. Kenesky, P. V Rucker, A. B. Smith, III, G. A. Orr, and S. B. Horwitz. A Photoaffinity Analogue of Discodermolide Specifically Labels a Peptide in β-Tubulin. Biochemistry. 2006, 45, 11762-11775. |
| 515. | A. Schön, J. C. Klein, N. Madani, D. Ng, A. B. Smith, III, J. Sodroski, and E. Freire. Binding Thermodynamics of a Small Molecular Weight CD4 Mimetic to NIV-1 gp120. Biochemistry. 2006, 45, 10973-10980. |
| 514. | A. B. Smith, III, M. Xian, and W.-S. Kim. The [1,5]-Brook Rearrangement: An Initial Application in Anion Relay Chemistry. J. Am. Chem. Soc. 2006, 128, 12368-12369. |
| 513. | P. J. Stephens, D. M. McCann, F. J. Devlin, and A. B. Smith, III. Determination of the Absolute Configurations of Natural Products via Density Functional Theory Calculations of Optical Rotation, Electronic Circular Dichroism and Vibrational Circular Dichroism: the Cytotoxic Sesqquiterpene Natural Products Quadrone, Subersenone, Suberosanone and Suberosenol A Acetate. J. Nat. Prod. 2006, 69 1055-1064. |
| 512. | A. B. Smith, III and V. Simov. Total Synthesis of the Marine Natural Product (–)-Clavosolide A. A Showcase for the Petasis-Ferrier Union/Rearrangement Tactic. Org. Lett. 2006, 8, 3315-3318. |
| 511. | A. B. Smith, III, L. Kürti, and A. K. Davulcu. A New Modular Indole Synthesis. Construction of the Highly Strained CDEF Parent Tetracycle of Nodulipsoric Acids A and B. Org. Lett. 2006, 8, 2167-2170. |
| 510. | S. Foister, L. L. Taylor, J.-J. Feng, W.-L. Chen, A. Lin, F.-C. Cheng, A. B. Smith, III, and R. F. Hirschmann. Design and Synthesis of a Potent Cystine-Free Cyclic Hexapeptide Agonist at the Human Urotensin Receptor. Org. Lett. 2006, 8, 1799-1802. |
| 509. | A. B. Smith, III, A. H. Davulcu, and L. Kürti. Indole Diterpenoid Synthetic Studies. Construction of the Heptacyclic Core of (–)-Nodulisporic Acid D. Org. Lett. 2006, 8, 1669-1672. |
| 508. | A. B. Smith, III, A. H. Davulcu, and L. Kürti. Indole Diterpenoid Synthetic Studies. The Total Synthesis of (+)-Nodulisporic Acid F. Org. Lett. 2006, 8, 1665-1668. |
| 507. | A. B. Smith, III and D.-S. Kim. A General, Convergent Strategy for the Construction of Indolizidine Alkaloids: Total Synthesis of (–)-Indolizidine 223AB and Alkaloid (–)-205B. J. Org. Chem. 2006, 71, 2547-2557. |
| 506. | A. B. Smith, III, E. F. Mesaros, and E. A. Meyer. Evolution of a Total Synthesis of (–)-Kendomycin Exploiting a Petasis-Ferrier Rearrangement/Ring-Closing Olefin Metathesis Strategy. J. Am. Chem. Soc. 2006, 128, 5292-5299. |
| 505. | A. B. Smith, III, T. M. Razler, R. M. Meis, and G. R. Pettit. The Design and Synthesis of a Potent Phorboxazole C(11-15) Acetal Analogue. Org. Lett. 2006, 8, 797-799. |
| 504. | G. S. Huang, L. Lopez-Barcons, R. Perez-Soler, B. S. Freeze, A. B. Smith, III, G. L. Goldberg, S. B. Horwitz, and H. McDaid. Potentiation of Taxol Efficacy by Discodermolide in Ovarian Carcinoma Xenograft-bearing Mice. Clin. Cancer Res. 2006, 12, 298-304. |
| 503. | A. B. Smith, III and M. Xian. Anion Relay Chemistry: An Effective Tactic for Diversity Oriented Synthesis. J. Am. Chem. Soc. 2006, 128, 66-67. |
| 502. | A. B. Smith, III, A. K. Charnley, H. Harada, J. J. Beiger, L.-D. Cantin, C. S. Kenesky, R. Hirschmann, S. Munshi, D. B. Olsen, M. W. Stahlhut, W. A. Schleif, and L. C. Kuo. Design, Synthesis and Biological Evaluation of Monopyrrolinone-Based HIV-1 Protease Inhibitors Possessing Augmented P2 Side-Chains. Bioorg. Med. Chem. Lett. 2006, 16, 859-863. |
| 501. | A. B. Smith, III. Editorial 2006: Exciting and Challenging Times for Organic Letters. Org. Lett. 2006, 8, 1-2. |
| 2005 | |
|---|---|
| 500. | A. B. Smith, III, J. J. Beiger, A. H. Davulcu, and J. M. Cox. Preparation of [1 (Methoxymethylcarbamoyl)ethyl] Phosphonic Acid Bis(2,2,2-Trifluoroethyl) Ester: a Useful Intermediate in the Synthesis of Z-Unsatured N-Methoxy-N-Methylamides. Org. Syn. 2005, 82, 147-156. |
| 499. | S. Mani, H. Huang, S. Sundarababu, W. Liu, G. Kalpana, A. B. Smith, III, and S. B. Horwitz. Activation of the Steroid and Xenobiotic Receptor (hPXR or SXR) by Non-Taxane Microtubule Stabilizing Agents. Clin. Cancer Res. 2005, 11, 6359-6369. |
| 498. | A. B. Smith, III and M. Xian. Design, Synthesis, and Biological Evaluation of Simplified Analogues of (+)-Discodermolide. Additional Insights on the Importance of Diene and Lactone. Org. Lett. 2005, 7, 5229-5232. |
| 497. | C. Sun, S. E. Aspland, C. Ballatore, R. Castillo, A. B. Smith, III, and A. J. Castelino. The Design, Synthesis and Evaluation of Two Universal Doxorubicin-Linkers. Preparation of Conjugates that Retain Topoisomerase II Activity. Bioorg. Med. Chem. Lett. 2005, 16, 104-107. |
| 496. | A. B. Smith, III, P. V. Rucker, I. Brouard, B. S. Freeze, and S. B. Horwitz. Design, Synthesis and Biological Evaluation of Discodermolide Fluorescent and Photoaffinity Molecular Probes. Org. Lett. 2005, 7, 5199-5202. |
| 495. | A. B. Smith, III, Q. Han, P. A. S. Breslin, and G. K. Beauchamp. Synthesis and Assignment of Absolute Conformation of (–)-Oleocanthal: A Potent, Naturally Occurring Non-Steroidal Anti-Inflammatory and Anti-Oxidant Agent Derived from Extra Virgin Olive Oils. Org. Lett. 2005, 7, 5075-5078. |
| 494. | A. B. Smith, III, M. Xian, and F. Liu. Design, Synthesis and Biological Evaluation of C13-C14 Cyclopropane Analogs of Discodermolide. Org. Lett. 2005, 7, 4613-4616. |
| 493. | M. J. Fuertes, J. Kaur, P. Deb, B. S. Cooperman, and A. B. Smith, III. Design, Synthesis, and Evaluation of Octahydropyranopyrrole-Based Inhibitors of Mammalian Ribonucleotide Reductase. Biorg. Med. Chem. Lett. 2005, 15, 5146-5149. |
| 492. | A. B. Smith, III, T. M. Razler, G. R. Pettit, and J.-C. Chapuis. (+)-Phorboxazole A Synthetic Studies: Identification of Highly Cytotoxic C(45-46) Analogues. Org. Lett. 2005, 7, 4403-4406. |
| 491. | A. B. Smith, III, T. M. Razler, J. P. Ciavarri, T. Hirose, and T. Ishikawa. (+)-Phorboxazole A Synthetic Studies: A Highy Convergent Second Generation Synthesis of (+)-Phorboxazole A. Org. Lett. 2005, 7, 4399-4402. |
| 490. | G. Beauchamp, R. Keast, D. Morel, J. Lin, J. Pika, Q. Han, C.-H. Lee, A. B. Smith, III, and P. Breslin. Phytochemistry: Ibuprofen-like activity in extra-virgin olive oil. Nature 2005, 437, 45-46. |
| 490. | G. Beauchamp, R. Keast, D. Morel, J. Lin, J. Pika, Q. Han, C.-H. Lee, A. B. Smith, III, and P. Breslin. Phytochemistry: Ibuprofen-like activity in extra-virgin olive oil. Nature 2005, 437, 45-46. |
| 489. | C.G. Cho, W.-S. Kim and A. B. Smith, III. A Scalable Route to Trisubstituted (E)-Vinyl Bromides. Org. Lett 2005, 7, 3569-3572. |
| 488. | C. Ballatore, S. E. Aspland, R. Castillo, J. Desharnais, T. Eustaquio, C. Sun, A. J. Castellino, and A. B. Smith, III. A Facile Route to Paclitaxel C-10 Carbamates. Bioorg. Med. Chem. Lett. 2005, 15, 2477-2480. |
| 487. | A. B. Smith, III, B. S. Freeze, M. J. LaMarche, J. Sager, K. W. Kinzler, and B. Vogelstein. Discodermolide Analogues as the Chemical Components of Combination Bacteriolytic Therapy (COBALT). Bioorg. Med. Chem. Lett. 2005, 15, 3623-3626. |
| 486. | S. Neelamkavil, E. Birzin, J.-J. Feng, K.-H. Chen, A. Lin, F.-C. Chen, L. Taylor, E. R. Thornton, A. B. Smith, III, and R. Hirschmann. Replacement of Phe6, Phe7, and Phe11 of D-Trp8-Somatostatin-14 with L-Pyrazinylalanine. Predicted and Observed Effects on Binding Affinities at hstr2 and hstr4. An Unexpected Effect of the Chirality of Trp8 on NMR Spectra in Methanol. J. Med. Chem. 2005, 48, 4025-4030. |
| 485. | A. B. Smith, III and D.-S. Kim. Total Synthesis of the Neotropical Poison Frog (–) Alkaloid 205B. Org. Lett. 2005, 7, 3247-3250. |
| 484. | A. B. Smith, III, R. J. Fox, and J. A. Vanecko. (+)-Sorangicin A Synthetic Studies. Construction of the C(1-15) and C(16-29) Subtargets. Org. Lett. 2005, 7, 3099-3102. |
| 483. | J. Q. Trojanowski, A. B. Smith, III, D. Huryn, and V. M.-Y. Lee. Microtubule Stabilizing Drugs for Therapy of Alzheimer’s Disease And Other Neurodegenerative Disorders With Axonal Transport Impairments. Expert Opin. Pharmacother. 2005, 6, 683-685. |
| 482. | L. E. Klein, B. S. Freeze, A. B. Smith, III, and S. B. Horowitz. The microtubule stabilizing agent discodermolide is a potent inducer of accelerated senescence. Cell Cycle 2005, 4, 501-507. |
| 481. | T. Sunazuka, T. Hirose, N. Chikaraishi, Y. Harigaya, M. Hayashi, K. Komiyama, P. A. Sprengeler, A. B. Smith, II, and S. Ōmura. Absolute Stereochemistries and Total Synthesis of (±)-Macrosphelides, Potent, Orally Bioavailable Inhibitors of Cell-Cell Adhesion. Tetrahedron 2005, 61, 3789-3803. |
| 480. | A. B. Smith, III, E. F. Mesaros, and E. A. Meyer. Total Synthesis of (–)-Kendomycin Exploiting a Petasis-Ferrier Rearrangement/Ring-Closing Olefin Metathesis Strategy. J. Am. Chem. Soc. 2005, 127, 6948-6949. |
| 479. | S. J. Shaw, K. F. Sundermann, M. A. Burlingame, D. C. Myles, B. S. Freeze, M. Xian, I. Brouard, and A. B. Smith, III. Towards Understanding How the Lactone Moiety of Discodermolide Affects Activity. J. Am. Chem. Soc. 2005, 127, 6532-6533. |
| 478. | A. B. Smith, III, B. S. Freeze, M. Xian, and T. Hirose. Total Synthesis of (+)-Discodermolide: A Highly Convergent Fourth-Generation Approach. Org. Lett. 2005, 7, 1825-1828. |
| 477. | A. R. Angeles, I. Neagu, E. T. Birzin, E. R. Thornton, A. B. Smith, III, and R. Hirschmann. Synthesis and Binding Affinities of Novel SRIF-mimicking β-D-Glucosides Satisfying the Requirement for a π-Cloud at C1. Org. Lett. 2005, 7, 1121-1124. |
| 476. | S. Neelamkavil, B. P. Mowery, E. R. Thornton, A. B. Smith, III, and R. Hirschmann. A Practical Synthesis of Nα-Fmoc-L-Pyrazinylalanine via Schöllkopf’s Chiral Auxiliary. J. Peptide Res. 2005, 65, 139-142. |
| 475. | A. B. Smith, III, A. K. Charnley, E. F. Mesaros, O. Kikuchi, W. Wang, A. Benowitz, and R. Hirschmann. Design, Synthesis, and Biological Evaluation of Novel Pyrrolinone-Based Somatostatin Mimetics. Org. Lett. 2005, 7, 399-402. |
| 474. | A. B. Smith, III, B. S. Freeze, M. J. LaMarche, T. Hirose, I. Brouard, P. V. Rucker, M. Xian, D. C. Myles, K. F. Sundermann, S. J. Shaw, and M. A. Burlingame. Design, Synthesis, and Evaluation of Analogues of (+)-14-Normethyldiscodermolide. Org. Lett. 2005, 7, 315-318. |
| 473. | A. B. Smith, III, B. S. Freeze, M. J. LaMarche, T. Hirose, I. Brouard, P. V. Rucker, M. Xian, D. C. Myles, K. F. Sundermann, S. J. Shaw, and M. A. Burlingame. Design, Synthesis, and Evaluation of Carbamate-Substituted Analogs of (+)-Discodermolide. Org. Lett. 2005, 7, 311-314. |
| 472. | A. B. Smith, III, S. P. Walsh, M. Frohn, and M. O. Duffey. Diversity Oriented Synthesis of Polyketide Natural Products via Iterative Chemo- and Stereo-selective Functionalization of Polyenoates: Development of a Unified Approach for the C(1-19) Segments of Lituarines A, B, and C. Org. Lett 2005, 7, 139-142. |
| 471. | A. B. Smith, III. Editorial 2005. Org. Lett. 2005, 7, 1-2. |
| 2004 | |
|---|---|
| 470. | A. B. Smith, III, C. Sfouggatakis, D. B. Gotcehv, S. Shirakami, D. Bauer, W. Zhu, and V. A. Doughty. Spongistatin Synthetic Studies. Evolution of a Scalable Synthesis of the EF Fragment of (+) Spongistatin 1 Exploiting the Petasis-Ferrier Union/Rearrangement. Org. Lett. 2004, 6, 3637-3640. |
| 469. | J. Tang, E. Mei, J. Kaplan, C. Green, W. F. DeGrado, A. B. Smith III and R. M. Hochstrasser. 1. Probing Structural Dynamics of Individual Calmodulin: Peptide Complexes in Hydrogel by Single Molecule Confocal Microscopy. J. Phys. Chem. B. 2004, 108, 15910-15918. |
| 468. | A. B. Smith, III, C. M. Adams, S. A. Lodise-Barbosa, and A. P. Degnan. A unified approach to the tedanolides: total synthesis of (+)-13-deoxytedanolide. Proc. Natl. Acad. Sci. USA 2004, 101, 12042-12047. |
| 467. | A. B. Smith, III and M. O. Duffey. Bifunctional Molecular Linchpins: A Three-Component Coupling Protocol Employing 2-Bromoallyltrimethylsilane. Synlett, 2004, 1363-1366. |
| 466. | C. Fang, J. Wang, Y. S. Kim, A. K. Charnley, W. Barber-Armstrong, A. B. Smith, III, S. M. Decatur, and R. M. Hochstrasser. Two-Dimensional Infrared Spectroscopy of lsotopomers of an Alanine-rich α Helix. J. Phys. Chem. B, 2004, 108, 10415-10427. |
| 465. | L. H. Dang, C. Bettegowda, N. Agrawal, I. Cheong, D. Huso, P. Frost, F. Loganzo, L. Greenberger, J. Barkoczy, G. Pettit, A. B. Smith, III, H. Gurulingappa, S. Kahn, G. Parmigiani, K. Kinzler, S. Zhou, and B. Vogelstein. Targeting Vascular and Avascular Components of Tumors with C. novyi-NY and Anti-Microtubule Agents. Cancer Biology & Therapy 2004, 3, 326-337. |
| 464. | A. B. Smith, III, and C. M. Adams. Evolution of Dithiane-Based Strategies for the Construction of Architecturally Complex Natural Products. Acc. of Chem. Res. 2004, 37, 365-377. |
| 464. | A. B. Smith, III, and C. M. Adams. Evolution of Dithiane-Based Strategies for the Construction of Architecturally Complex Natural Products. Acc. of Chem. Res. 2004, 37, 365-377. |
| 463. | A. B. Smith, III, and S. M. Pitram. 2-Tetra-Butyldimethylsilyl-1,3–Dithiane. Electronic Encyclopedia of Reagents for Organic Synthesis, ed. L. Paquette, P. Fuchs, D. Crich, and P. Wipf. John Wiley & Sons |
| 462. | M. A. Burlingame, S. J. Shaw, K. F. Sundermann, D. Zhang, J. Petryka, E. Mendoza, F. Liu, D. C. Myles, M. J. LaMarche, T. Hirose, B. S. Freeze, and A. B. Smith, III. Design, synthesis and cytotoxicity of 7-deoxy aryl discodermolide analogues. Bioorg. Med. Chem. Lett. 2004, 14, 2335-2338. |
| 461. | N. Madani, A. L. Perdigoto, K. Srinivasan, J. M. Cox, J. J. Chruma, J. LaLonde, M. Head, A. B. Smith, III, J. G. Sodroski. Localized Changes in the gp120 Envelope Glycoprotein Confer Resistance to Human Immunodeficiency Virus Entry Inhibitors, BMS-806 and #155. J. Virol. 2004, 78, 3742-3752. |
| 460. | Z. Si, N. Madani, J. M. Cox, J. J. Chruma, J. C. Klein, A. Schoen, N. Phan, L. Wang, A. C. Biorn, S. Cocklin, I. Chaiken, E. Freire, A. B. Smith, III, and J. G. Sodroski. Small-molecule inhibitors of HIV-1 entry block receptor-induced conformational changes in the viral envelope glycoproteins. Proc. Natl. Acad. Sci. USA. 2004,101, 5036-5041. |
| 459. | A. B. Smith, III, and D.-S. Kim. Multicomponent Linchpin Coupling of Silyl Dithiane Employing an N-Ts Azirdine as a Second Electrophile: Synthesis of (–)-lndolizidine 223 AB. Org. Lett. 2004, 6, 1493-1495. |
| 458. | A. B. Smith, III, and R. J. Fox. Construction of a C(30-38) Dioxabicyclo[3.2.1]octane Subtarget for (+) Sorangicin A, Exploiting a Regio- and Stereocontrolled Acid-Catalyzed Epoxide Ring Opening. Org. Lett. 2004, 6, 1477-1480. |
| 457. | A. B. Smith, III, J. J. Chruma, Q. Han, and J. Barbosa. Complestatin synthetic studies: the effects of the amino acid configuration on peptide backbone conformation in the common western BCD macrocycle. Bioorg. Med. Chem. Lett. 2004, 14, 1697-1702. |
| 456. | L. Abrous, P. Jokiel, S. R. Friedrich, J. Hynes, Jr., A. B. Smith, III, and R. Hirschmann. Novel Chimeric Scaffolds to Extend the Exploration of Receptor Space: Hybrid β-D-Glucose-Benzoheterodiazepine Structures for Broad Screening. Effect of Amide Alkylation on the Course of Cyclization Reactions. J. Org. Chem. 2004, 69, 280-302. |
| 455. | A. B. Smith, III. Editorial 2004: The Next Five Years. Org. Lett. 2004, 6, 1-2. |
| 2003 | |
|---|---|
| 454. | C. Fang, J. Wang, A. K. Charnley, W. Barber-Armstrong, A. B. Smith, III, S. M. Decatur, and R. M. Hochstrasser. Two-dimensional infrared measurements of the coupling of amide modes of an α-helix. Chem. Phys. Lett. 2003, 382, 586-592. |
| 453. | R. Hirschmann and A. B. Smith, III. Search for Biologically Active Peptidomimetics of β-Turns and β-Strands. Designed Scaffolds and Serendipitous Observations. Peptide Revolution: Genomics, Proteomics & Therapeutics. eds. M. Chorev and T. K. Sawyer. American Peptide Society, 2003. |
| 452. | A. B. Smith, III, and H. Cui. lndole Diterpine Synthetic Studies. 1. Total Synthesis of (–) 21 lsopentenylpaxilline. Helv. Chim. Acta 2003, 86, 3908-3938. |
| 451. | A. B. Smith, III, B. Scott Freeze, I. Brouard, and T. Hirose. A Practical Improvement, Enhancing the Large-Scale Synthesis of (+)-Discodermolide: A Third-Generation Synthesis. Org. Lett. 2003, 5, 4405-4408. |
| 450. | A. B. Smith, III. Sulfur. C&E N. 2003, 81, 60. |
| 449. | A. B. Smith, III, S. M. Pitram, A. M. Boldi, M. J. Gaunt, C. Sfouggatakis, and W. H. Moser. Multicomponent Linchpin Couplings. Reaction of Dithiane Anions with Terminal Epoxides, Epichlorohydrin, and Vinyl Epoxides: Efficient, Rapid, and Stereocontrolled Assembly of Advanced Fragments for Complex Molecule Synthesis. J. Am. Chem. Soc. 2003, 125, 14435-14445. |
| 448. | A. B. Smith, III, S. M. Pitram, and M. J. Fuertes. (+)-Rimocidin Synthetic Studies. Construction of an Advanced C(1-18) Polyol Fragment. Org. Lett. 2003, 5, 2751-2754. |
| 447. | A. B. Smith, III, Y. S. Cho, G. R. Pettit, and R. Hirschmann. Design, synthesis, and evaluation of azepine-based cryptophycin mimetics. Tetrahedron 2003, 59, 6991-7009. |
| 446. | A. B. Smith, III, N. Kanoh, H. lshiyama, N. Minakawa, J. D. Rainier, R. A. Hark, Y. S. Cho, H. Cui, and W. M. Moser. Tremorgenic lndole Alkaloids. The Total Synthesis of (–) Penitrem D. J. Am. Chem. Soc. 2003, 125, 8228-8237. |
| 445. | V. Prasad, E. T. Birzin, C. T. McVaugh, R. D. van Rijn, S. P. Rohrer, G. Chicchi, D. J. Underwood, E. R. Thornton, A. B. Smith, III, and R. Hirschmann. Effects of Heterocyclic Aromatic Substituents on Binding Affinities at Two Distinct Sites of Somatostatin Receptors. Correlation with the Electrostatic Potential of the Substituents. J. Med. Chem. 2003, 46, 1858-1869. |
| 444. | A. B. Smith, III, L.-D. Cantin, A. Pasternak, L. Guise-Zawacki, W. Yao, A. Charnleyl J. Barbosa, P. A. Sprengeler, R. Hirschmann, S. Munshi, D. B. Olsen, W. A. Schleif and L. C. Kuo. Design, Synthesis and Biological Evaluation of Monopyrrolinone-Based HIV-1 Protease Inhibitors. J. Med. Chem. 2003, 46, 1831-1844. |
| 443. | S. N. Savinov, R. Hirschmann, S. J. Benkovic and A. B, Smith, III. Investigation of an Antibody-Ligase. Evidence for Strain-Induced Catalysis. Bioorg. Med. Chem. Lett. 2003, 13, 1321-1324. |
| 442. | P. V. Murphy, J. L. O’Brien, L. J. Gorey-Feret, and A. B. Smith, Ill. Synthesis of novel HIV-1 protease inhibitors based on carbohydrate scaffolds. Tetrahedron 2003, 59, 2259-2271. |
| 441. | A. B. Smith, III, W. Zhu, S. Shirakami, C. Sfouggatakis, V. A. Doughty, C. S. Bennett, and Y. Sakamoto. Total Synthesis of (+)-Spongistatin 1. An Effective, Second-Generation Construction of an Advanced EF Wittig Salt, Fragment Union, and Final Elaboration. Org. Lett. 2003, 5, 761-764. |
| 440. | A. B. Smith, III, and H. Cui. Total Synthesis of (–)-21-lsopentenylpaxiline. Org. Lett. 2003, 5, 587-590. |
| 439. | Smith, Amos B.; Adams, Christopher M.; Barbosa, Stephanie A. Lodise; Degnan, Andrew P. Total Synthesis of (+)-13-Deoxytedanolide. Journal of the American Chemical Society (2003), 125(2), 350-351. |
| 438. | A. B. Smith, III. Editorial 2003: Year Four. Org. Lett. 2003, 5, 1-2. |
| 2002 | |
|---|---|
| 437. | A. B. Smith, III, S. M. Pitram, M. J. Gaunt, and S. A. Kozmin. Dithiane Additions to Vinyl Epoxides: Steric Control Over the SN2 and SN2′ Manifolds. J. Am. Chem. Soc. 2002, 124, 14516-14517. |
| 436. | A. B. Smith, III, D. Lee, C. M. Adams, and M. C. Kozlowski. Sml2-Promoted Oxidation of Aldehydes in the Presence of Electron Rich Heteroatoms. Org. Lett. 2002, 4, 4539-4541. |
| 435. | A. B. Smith, III, S. N. Savinov, U. Manjappara, and I. M. Chaiken. Peptide-Small Molecule Hybrids via Orthogonal Deprotection-Chemoselective Conjugation to Cysteine-Anchored Scaffolds. A Model Study. Org. Lett. 2002, 4, 4041-4044. |
| 434. | Smith, Amos B.; Safonov, Igor G.; Corbett, R. Michael. Total Syntheses of (+)-Zampanolide and (+)-Dactylolide Exploiting a Unified Strategy. Journal of the American Chemical Society (2002), 124(37), 11102-11113. |
| 433. | A. B. Smith, III and J. Zheng. Total synthesis of salicylihalamide A and related congeners. Tetrahedron 2002, 58, 6455-6471. |
| 432. | A. B. Smith, III, R. M. Corbett, G. R. Pettit, J.-C. Chapuis, J. M. Schmidt, E. Hamell and M. Katherine Jung. Synthesis and Biological Evaluation of a Spongistatin AB-Spiroketal Analog. Bioorg. Med. Chem. Lett. 2002, 12, 2039-2042. |
| 431. | P. V. Murphy, J. L. O’Brien, L. J. Gorey-Feret, and A. B. Smith, III. Structure-Based Design and Synthesis of HIV-1 Protease Inhibitors Employing β-D-Mannopyranoside Scaffolds. Bioorg. Med.Chem. Lett. 2002, 12, 1763-1766. |
| 430. | A. B. Smith, III, V. A. Doughty, C. Sfouggatakis, C. S. Bennett, J. Koyanagi and M. Takeuchi. Spongistatin Synthetic Studies. An Efficient, Second-Generation Construction of an Advanced ABCD Intermediate. Org. Lett. 2002, 4, 783-786. |
| 429. | A. B. Smith, III and I. G. Safonov. Total Synthesis of (+)-Dactylolide. Org. Lett. 2002, 4, 635-637. |
| 428. | A. B. Smith, III. Editorial: The First Three Years. Org. Lett. 2002, 4, 1. |
| 427. | A. B. Smith, III and M. Frohn. Lituarine Synthetic Studies. An Efficient, Stereocontrolled Construction of the Common C(7-19) Tricyclic Spiroketal Fragment. Org. Lett, 2001, 3, 3979-3982; Correction: Org. Lett. 2002, 4, 4183. |
| 2001 | |
|---|---|
| 426. | A. B. Smith, III, Y. S. Cho, L. E. Zawacki, R. Hirschmann, and G. R. Pettit. First Generation Design, Synthesis, and Evaluation of Azepine-Based Cryptophycin Analogs. Org. Lett. 2001, 3, 4063-4066. |
| 425. | A. B. Smith, III, Y. S. Cho, and H. lshiyama. Nodulisporic Acid A Synthetic Studies. 2. Construction of an Eastern Hemisphere Subtarget. Org. Lett. 2001, 3, 3971-3974. |
| 424. | A. B. Smith, III, H. lshiyama, Y. S. Cho, and K. Ohmoto. Nodulisporic Acid A Synthetic Studies. 1. Overall Strategy and Construction of a Western Hemisphere Subtarget. Org. Lett. 2001, 3, 3967-3970. |
| 423. | A. B. Smith, III, I. G. Safonov, and R. M. Corbett. Total Synthesis of (+)-Zampanolide. J. Am. Chem. Soc. 2001, 123, 12426-12427. |
| 422. | P. V. Murphy, J. L. O’Brien, and A. B. Smith, III. Stereospecific syntheses of β D allopyranosides by dihydroxylation of β-D-erythro-2,3-dideoxyhex-2-enopyranosides. Carbohydr. Res. 2001, 334, 327-335. |
| 421. | A. B. Smith, III, K. P. Minbiole, and S. Freeze. Facile Assembly of 2,4-Orthogonal-Functionalized Oxazoles: Useful Bidirectional Linchpins. Synlett 2001, 1739-1742. |
| 420. | Smith, Amos B., III; Minbiole, Kevin P.; Verhoest, Patrick R.; Schelhaas, Michael. Total synthesis of (+)-phorboxazole A exploiting the Petasis-Ferrier rearrangement. Journal of the American Chemical Society (2001), 123(44), 10942-10953. |
| 419. | Martello, L. A.; LaMarche, M. J.; He, L.; Beauchamp, T. J.; Smith, A. B.; Horwitz, S. B. The relationship between Taxol and (+)-discodermolide: synthetic analogs and modeling studies. Chemistry & Biology (2001), 8(9), 843-855. |
| 418. | S. B. Horwitz, L. A. Martello, C.- P. H. Yang, A. B. Smith, III, and H. M. McDaid. Discodermolide and Taxol: A Synergistic Drug Combination in Human Carcinoma Cell Lines. In Anticancer Agents: Frontiers in Cancer Chemotherapy. Ojima, I.; Vite, G. D.; Karh-Heinz Altmannl K.-H., (Eds.). ACS Symp. Series 796, American Chemical Society: Washington, DC, 2001; pp 81-96. |
| 417. | Smith, Amos B., III; Adams, Christopher M.; Kozmin, Sergey A.; Paone, Daniel V. Total Synthesis of (-)-Cylindrocyclophanes A and F Exploiting the Reversible Nature of the Olefin Cross Metathesis Reaction. Journal of the American Chemical Society (2001), 123(25), 5925-5937. |
| 416. | A. B. Smith, III and J. Zheng. A First Generation Total Synthesis of (+)-Salicylihalamide A. Synlett, 2001,1019-1024. |
| 415. | A. B. Smith, III and B. M. Brandt. Total Synthesis of (–)-Callystatin A. Org. Lett. 2001, 3, 1685-1688. |
| 414. | A. B. Smith, III, P. R. Verhoest, K. P. Minbiole, and M. Schelhaas. Total Synthesis of (+) Phorboxazole A. J. Am. Chem. Soc. 2001, 123, 4834-4836. |
| 413. | L. Abrous, J. Hynes, Jr., S. R. Friedrich, A. B. Smith, III, and R. Hirschmann. Design and Synthesis of Novel Scaffolds for Drug Discovery: Hybrids of β-D-Glucose with 1,2,3,4 Tetrahydrobenzo[e][1,4]diazepin-5-one, the Corresponding 1-Oxazepinel and 2- and 4-Pyridyldiazepones. Org. Lett. 2001, 3, 1089-1092. |
| 412. | A. B. Smith, III, M. J. LaMarche, and M. Falcone-Hindley. Solution Structure of (+) Discodermolide. Org. Lett. 2001, 3, 695-698. |
| 411. | A. B. Smith, III, C. M. Adams, and S. A. Kozmin. On the Reversible Nature of the Olefin Cross Metathesis Reaction. J. Am. Chem. Soc. 2001, 123, 990-991. |
| 410. | Smith, Amos B., III; Lin, Qiyan; Doughty, Victoria A.; Zhuang, Linghang; McBriar, Mark D.; Kerns, Jeffrey K.; Brook, Christopher S.; Murase, Noriaki; Nakayama, Kiyoshi. The spongistatins: architecturally complex natural products. Part two. Synthesis of the C(29-51) subunit, fragment assembly, and final elaboration to (+)-spongistatin 2. Angewandte Chemie, International Edition (2001), 40(1), 196-199. |
| 409. | A. B. Smith, III, V. A. Doughty, Q. Lin, L.-H. Zhuang, M. D. McBriar, A. M. Boldi, W. H. Moser, N. Murase, K. Nakayama, and M. Sobukawa. The Spongistatins: Architecturally Complex Natural Products. Part One: A Formal Synthesis of (+)-Spongistatin 1 by Construction of an Advanced ABCD Fragment. Angew. Chem. lnt. Ed. 2001, 40, 191-195. |
| 2000 | |
|---|---|
| 408. | R. Hirschmann, L. Ducry, and A. B. Smith, III. The Development of an Efficient Regio- and Stereoselective Route to Libraries Based on the β-D-Glucose Scaffold. J. Org. Chem. 2000, 65, 8307-8316. |
| 407. | A. B. Smith, III, L. Ducry, R. M. Corbett and R. Hirschmann. Intramolecular Hydrogen-Bond Participation in Phosphonylammonium Salt Formation. Org. Lett. 2000, 2, 3887-3890. |
| 406. | J. D. Rainier and A. B. Smith, III. Polyene cyclizations to indole diterpenes. The first synthesis of (+) emindole SA using a biomimetic approach. Tetrahedron Lett. 2000, 41, 9419-9423. |
| 405. | A. B. Smith, III, T. Nittoli, P. A. Sprengeler, J. J.-W. Duan, R.-Q. Liu, and R. F. Hirschmann. Design, Synthesis, and Evaluation of a Pyrrolinone-Based Matrix Metalloprotease Inhibitor. Org. Lett, 2000, 2, 3809-3812. |
| 404. | J. Liu, D. J. Underwood. M. A. Cascieri, S. P. Rohrer, L.-D. Cantin, G. Chicchi, A. B. Smith, III and R. Hirschmann. Synthesis of a Substance P Antagonist with Somatostatin Scaffold: Factors Affecting Agonism/Antagonism at GPCRs and the Role of Pseudosymmetry. J. Med. Chem. 2000, 43, 3827-3831. |
| 403. | Smith, Amos B., III; Kanoh, Naoki; Ishiyama, Haruaki; Hartz, Richard A. Total Synthesis of (-)-Penitrem D. Journal of the American Chemical Society (2000), 122(45), 11254-11255. |
| 402. | Smith, Amos B., III; Wang, Wenyong; Sprengeler, Paul A.; Hirschmann, Ralph. Design, Synthesis, and Solution Structure of a Pyrrolinone-Based b-Turn Peptidomimetic. Journal of the American Chemical Society (2000), 122(44), 11037-11038. |
| 401. | M. R. Stetzer, P. A. Heiney, P. W. Stephens, R. E. Dinnebier, Q. Zhu, A. R. McGhie, R. M. Strongin, B. M. Brandt, and A. B. Smith, III. Structure and phase transitions of the 6,6-cyclopropane isomer of C61H2. Phys. Rev. B 2000, 62, 9305-9315. |
| 400. | A. B. Smith, Ill, T. J. Beauchamp, M. J. LaMarche, M. D. Kaufman, Y. Qiu, H. Arimoto, D. R. Jones, and K. Kobayashi. Evolution of a Gram-Scale Synthesis of (+)-Discodermolide. J. Am. Chem. Soc. 2000, 122, 8654-8664. |
| 399. | K. H. Lee, G. L. Olson, D. R. Bolin, A. B. Benowitz, P. A. Sprengeler, A. B. Smith, III, R. F. Hirschmann, and D. C. Wiley. The Crystal Structure of a Pyrrolinone-Peptide Hybrid Ligand Bound to the Human Class II MHC Protein HLA-DR1. J. Am. Chem. Soc. 2000, 122, 8370-8375. |
| 398. | A. B. Smith, Ill. Editorial: A Year of Firsts for Organic Letters. Org. Lett. 2000, 2, 1985-1986. |
| 397. | A. B. Smith, Ill, H. Liu, H. Okumura, D. A. Favor, and R. Hirschmann. Synthesis of Polypyrrolinones on Solid Support. Org. Lett. 2000, 2, 2041-2044. |
| 396. | A. B. Smith, III, H. Liu, and R. Hirschmann. A Second-Generation Synthesis of Polypyrrolinone Nonpeptdomimetics: Prelude to the Synthesis of Polypyrrolinones on Solid Support. Org. Lett. 2000, 2, 2037-2040. |
| 395. | R. K. Kondru, D. N. Beratan, G. K. Friestad, A. B. Smith, Ill, and P. Wipf. Chiral Action at a Distance: Remote Substituent Effects on the Optical Activity of Calyculins A and B. Org. Lett. 2000, 2, 1509-1512. |
| 394. | A. B. Smith, Ill, and Z. Wan. Total Synthesis of the Ansamycin Antibiotic (+) Thiazinotrienomycin E. J. Org. Chem. 2000, 65, 3738-3753. |
| 393. | L. A. Martello, H. M. McDaid, D. L. Regl, C.-P. H. Yang, D. Meng, T. R. R. Pettus, M. D. Kaufman, H. Arimoto, S. J. Danishefsky, A. B. Smith, III, and S. B. Horwitz. Taxol® and Discodermolide Represent a Synergistic Drug Combination in Human Carcinoma Cell Lines. Clinical Cancer Research 2000, 6, 1978-1987. |
| 392. | A. B. Smith, Ill, S. A. Kozmin, C. M. Adams, and D. V. Paone. Assembly of (–) Cylindrocyclophanes A and F via Remarkable Olefin Metathesis Dimerizations. J. Am. Chem. Soc. 2000, 122, 4984-4985. |
| 391. | A. B. Smith, III, J. P. Sestelo, and P. G. Dormer. A Highly Efficient Synthetic Route to (–) Furaquinocin C. Heterocycles 2000, 52, 1315-1328. |
| 390. | T. Sunazuka, T. Hirose, T. Shirahata, Y. Harigaya, M. Hayashi, K. Komiyama, S. Ōmura, and A. B. Smith, III. Total Synthesis of (+)-Madinoline A and (–)-Madinoline B, Potent, Selective Inhibitors of Interleukin 6. Determination of the Relative and Absolute Configurations. J. Am. Chem. Soc. 2000, 122, 2122-2123. |
| 389. | D. B. Smithrud, P. A. Benkovic, S. J. Benkovic, V. Roberts, J. Liu, I. Neagu, S. Iwama, B. W. Phillips, A. B. Smith, III, and R. Hirschmann. Cyclic peptide formation catalyzed by an antibody ligase. Proc. Nat. Acad. Sci. 2000, 97, 1953-1958. |
| 388. | P. W. Schiller, I. Berezowska, T. M.-D. Nguyen, R. Schmidt, C. Lemieux, N. N. Chung, M. L. Falcone-Hindley, W. Yao, J. Liu, S. Iwama, A. B. Smith, III, and R. Hirschmann. Novel Ligands Lacking a Positive Charge for the δ and μ-Opioid Receptors. J. Med. Chem. 2000, 43, 551-559. |
| 387. | A. B. Smith, III. Editorial 2000. Org. Lett. 2000, 2, 1-2. |
| 1999 | |
|---|---|
| 386. | A. B. Smith, III and S. M. Pitram. Multicomponent Linchpin Couplings of SilyI Dithianes: Synthesis of the Schreiber C(16-18) Trisacetomide Subtarget for Mycoticin A and B. Org. Lett. 1999, 1, 2001-2004. |
| 385. | A. B. Smith, III, and J. R. Empfield. Synthetic Strategies Towards the Total Synthesis of Phyllanthocin and Breynolide. Application of Stereochemically Linear and Convergent Strategies. Chem. Pharm. Bull. 1999, 47, 1671-1678. |
| 384. | Smith, Amos B., III; Friestad, Gregory K.; Barbosa, Joseph; Bertounesque, Emmanuel; Duan, James J.-W.; Hull, Kenneth G.; Iwashima, Makoto; Qiu, Yuping; Spoors, P. Grant; Salvatore, Brian A. Total Synthesis of (+)-Calyculin A and (-)-Calyculin B: Cyanotetraene Construction, Asymmetric Synthesis of the C(26-37) Oxazole, Fragment Assembly, and Final Elaboration. Journal of the American Chemical Society (1999), 121(45), 10478-10486. |
| 383. | A. B. Smith, III, G. K. Friestad, J. Barbosa, E. Bertounesque, K. G. Hull, M. Iwashima, Y. Qiu, B. A. Salvatore, P. G. Spoors, and J. J.-W. Duan. Total Synthesis of (+)-Calyculin A and (–) Calyculin B: Asymmetric Synthesis of the C(9-25) Spiroketal Dipropionate Subunit. J. Am. Chem. Soc. 1999, 121, 10468-10477. |
| 382. | A. B. Smith, III, M. D. Kaufmann, T. J. Beauchamp, M. J. LaMarche, and H. Arimoto. Gram-Scale Synthesis of (+)-Discodermolide. Org. Lett. 1999, 1, 1823-1826. |
| 381. | A. B. Smith, III and Z. Wan. Total Synthesis of (+)-Thiazinotrienomycin E. Org. Lett. 1999, 1, 1491-1494. |
| 380. | A. B. Smith, III, N. Kanoh, N. Minakawa, J. D. Rainier. F. R. Blase, and R. A. Hartz. Tremorgenic Indole Alkaloids. Assembly of the A, F and I Rings of Penitrem D. Observation of an Unexpected Stereochemical Outcome. Org. Lett. 1999, 1, 1263-1266. |
| 379. | Smith, Amos B., III; Benowitz, Andrew B.; Sprengeler, Paul A.; Barbosa, Joseph; Guzman, Mark C.; Hirschmann, Ralph; Schweiger, Edwin J.; Bolin, David R.; Nagy, Zoltan; Campbell, Robert M.; Cox, Donald C.; Olson, Gary L. Design and Synthesis of a Competent Pyrrolinone-Peptide Hybrid Ligand for the Class II Major Histocompatibility Complex Protein HLA-DR1. Journal of the American Chemical Society (1999), 121(40), 9286-9298. |
| 378. | A. B. Smith, III, and S. A. Lodise. Synthesis of Tedanolide and 13-Deoxytedanolide. Assembly of a Common C(1)-C(11) Subtarget. Org. Lett. 1999, 1, 1249-1252. |
| 377. | S. Liehr, J. Barbosa, A. B. Smith, III, and B. S. Cooperman, Synthesis and Biological Activity of Cyclic Peptide Inhibitors of Ribonucleotide Reductase. Org. Lett. 1999, 1, 1201-1204. |
| 376. | A. B. Smith, III, K. P. Minbiole, P. R. Verhoest, and T. J. Beauchamp. Phorboxazole Synthetic Studies. 2. Construction of a C(20-28) Subtarget; a Further Extension of the Petasis-Ferrier Rearrangement. Org. Lett. 1999, 1, 913-916. |
| 375. | A. B. Smith, III, P. R. Verhoest, K. P. Minbiole, and J. J. Lim. Phorboxazole Synthetic Studies. 1. Construction of a C(3-19) Subtarget Exploiting an Extension of the Petasis-Ferrier Rearrangement. Org. Lett. 1999, 1, 909-912. |
| 374. | P. A. Heiney, M. R. Stetzer, O. Y. Mindyuk, E. DiMasi, A. R. McGhie, H. Liu, and A. B. Smith, III. Langmuir Films of Amphiphilic Crown Ethers. J. Phys. Chem. B 1999, 103, 6206-6214. |
| 373. | A. B. Smith, III. Editorial. Org. Lett. 1999, 1, 1. |
| 372. | E. D. Soli, A. S. Manoso, M. C. Patterson, P. Deshong, D. A. Favor, R. Hirschmann and A. B. Smith, III. Azide and Cyanide Displacements via Hypervalent Silicate Intermediates. J. Org. Chem. 1999, 64, 3171-3177. |
| 371. | Smith, Amos B., III; Kozmin, Sergey A.; Paone, Daniel V. Total Synthesis of (-)-Cylindrocyclophane F. Journal of the American Chemical Society (1999), 121(32), 7423-7424. |
| 370. | Smith, Amos B., III; Kanoh, Naoki; Minakawa, Noriaki; Rainier, Jon D.; Hartz, Richard A.; Clark, William M.; Haseltine, John N. Total synthesis of penitrem D. Tennen Yuki Kagobutsu Toronkai Koen Yoshishu (1999), 41st 55-60. |
| 369. | Sunazuka, T.; Hirose, T.; Shirahata, T.; Harigaya, Y.; Hayashi, M.; Komiyama, K.; Smith, A. B., III; Omura, S. Relative and absolute stereochemistries and total syntheses of madindolines A and B, potent, selective inhibitors of IL-6 activity. Tennen Yuki Kagobutsu Toronkai Koen Yoshishu (1999), 41st 49-54. |
| 368. | Smith, Amos B., III; Favor, David A.; Sprengeler, Paul A.; Guzman, Mark C.; Carroll, Patrick J.; Furst, George T.; Hirschmann, Ralph. Molecular modeling, synthesis, and structures of N-methylated 3,5-linked pyrrolin-4-ones toward the creation of a privileged nonpeptide scaffold. Bioorganic & Medicinal Chemistry (1999), 7(1), 9-22. |
| 1998 | |
|---|---|
| 367. | Smith, Amos B., III; Sasho, Setsuya; Barwis, Bari A.; Sprengeler, Paul; Barbosa, Joseph; Hirschmann, Ralph; Cooperman, Barry S. Design and synthesis of a tetrahydropyran-based inhibitor of mammalian ribonucleotide reductase. Bioorganic & Medicinal Chemistry Letters (1998), 8(22), 3133-3136. |
| 366. | Smith, Amos B., III; Cho, Young Shin; Friestad, Gregory K. Convenient Wacker oxidations with substoichiometric cupric acetate. Tetrahedron Letters (1998), 39(48), 8765-8768. |
| 365. | Smith, Amos B. ,III; Benowitz, Andrew B.; Guzman, Mark C.; Sprengeler, Paul A.; Hirschmann, Ralph; Schweiger, Edwin J.; Bolin, David R.; Nagy, Zoltan; Campbell, Robert M.; Cox, Donald C.; Olson, Gary L. Design, synthesis, and evaluation of a pyrrolinone-peptide hybrid ligand for the class II MHC protein HLA-DR1. Journal of the American Chemical Society (1998), 120(48), 12704-12705. |
| 364. | Gidalevitz, David; Mindyuk, Oksana Y.; Stetzer, MacKenzie R.; Heiney, Paul A.; Kurnaz, M. Levent; Schwartz, Daniel K.; Ocko, Benjamin M.; McCauley, John P., Jr.; Smith, Amos B., III. A Conformational Phase Transition in a Langmuir Film of an Amphiphilic Azacrown. Journal of Physical Chemistry B (1998), 102(35), 6688-6691. |
| 363. | Smith, Amos B., III; Friestad, Gregory K.; Duan, James J.-W.; Barbosa, Joseph; Hull, Kenneth G.; Iwashima, Makoto; Qiu, Yuping; Spoors, P. Grant; Bertounesque, Emmanuel; Salvatore, Brian A. Total Synthesis of (+)-Calyculin A and (-)-Calyculin B. Journal of Organic Chemistry (1998), 63(22), 7596-7597. |
| 362. | Arimoto, Hirokazu; Kaufman, Michael D.; Kobayashi, Kaoru; Qiu, Yuping; Smith, Amos B., III. Anomalous epoxide formation upon Wittig olefination with 1-iodoethyl triphenylphosphonium ylide. Synlett (1998), (7), 765-767. |
| 361. | Khong, Anthony; Jimenez-Vazquez, Hugo A.; Saunders, Martin; Cross, R. James; Laskin, Julia; Peres, Tikva; Lifshitz, Chava; Strongin, Rob; Smith, Amos B., III. An NMR Study of He2 Inside C70. Journal of the American Chemical Society (1998), 120(25), 6380-6383. |
| 360. | Hirschmann, Ralph; Yao, Wenqing; Arison, Byron; Maechler, Laurie; Rosegay, Avery; Sprengeler, Paul A.; Smith, Amos B., III. Synthesis of the first tricyclic homodetic peptide. use of coordinated orthogonal deprotection to achieve directed ring closure. Tetrahedron (1998), 54(25), 7179-7202. |
| 359. | Smith, Amos B., III; Ott, Gregory R. Total Syntheses of (-)-Macrolactin A, (+)-Macrolactin E, and (-)-Macrolactinic Acid: An Exercise in Stille Cross-Coupling Chemistry. Journal of the American Chemical Society (1998), 120(16), 3935-3948. |
| 358. | Hirschmann, Ralph; Hynes, John, Jr.; Cichy-Knight, Maria A.; van Rijn, Rachel D.; Sprengeler, Paul A.; Spoors, P. Grant; Shakespeare, William C.; Pietranico-Cole, Sherrie; Barbosa, Joseph; Liu, Josephine; Yao, Wenqing; Rohrer, Susan; Smith, Amos B., III. Modulation of Receptor and Receptor Subtype Affinities Using Diastereomeric and Enantiomeric Monosaccharide Scaffolds as a Means to Structural and Biological Diversity. A New Route to Ether Synthesis. Journal of Medicinal Chemistry (1998), 41(9), 1382-1391. |
| 357. | Smith, Amos B., III; Barbosa, Joseph. (+)-Thiazinotrienomycin E: relative and absolute stereochemistry. Tetrahedron Letters (1998), 39(19), 2891-2894. |
| 356. | Sudoh, Masao; Pauletti, Giovanni M.; Yao, Wenqing; Moser, William; Yokoyama, Akihisa; Pasternak, Alexander; Sprengeler, Paul A.; Smith, Amos B., III; Hirschmann, Ralph; Borchardt, Ronald T. Transport characteristics of peptidomimetics. Effect of the pyrrolinone bioisostere on transport across Caco-2 cell monolayers. Pharmaceutical Research (1998), 15(5), 719-725. |
| 355. | Smith, Amos B.; Lin, Qiyan. Synthesis and in vitro cancer cell growth inhibitory activity of monocyclic model compounds containing spongistatin triene side-chains. Bioorganic & Medicinal Chemistry Letters (1998), 8(6), 567-568. |
| 354. | Smith, Amos B., III; Condon, Stephen M.; McCauley, John A. Total Synthesis of Immunosuppressants: Unified Strategies Exploiting Dithiane Couplings and s-Bond Olefin Constructions. Accounts of Chemical Research (1998), 31(1), 35-46. |
| 354. | Smith, Amos B., III; Condon, Stephen M.; McCauley, John A. Total Synthesis of Immunosuppressants: Unified Strategies Exploiting Dithiane Couplings and s-Bond Olefin Constructions. Accounts of Chemical Research (1998), 31(1), 35-46. |
| 1997 | |
|---|---|
| 353. | A.B. Smith, III. Organic Syntheses, John Wiley & Son, Inc.: New York, 1997; Vol. 50. |
| 352. | Smith, Amos B., III; Chen, Sean S.-Y.; Nelson, Frances C.; Reichert, Janice M.; Salvatore, Brian A. Total Syntheses of (+)-Acutiphycin and (+)-trans-20,21-Didehydroacutiphycin. Journal of the American Chemical Society (1997), 119(45), 10935-10946. |
| 351. | Gidalevitz, David; Mindyuk, Oksana Y.; Heiney, Paul A.; Ocko, Benjamin M.; Henderson, Philippe; Ringsdorf, Helmut; Boden, Neville; Bushby, Richard J.; Martin, Philip S.; Strzalka, Joseph; McCauley, John P., Jr.; Smith, Amos B., III. Structure of Discotic Liquid Crystalline Compounds at the Air-Water Interface. Journal of Physical Chemistry B (1997), 101(50), 10870-10875. |
| 350. | Smith, Amos B., III; Lin, Qiyan; Nakayama, Kiyoshi; Boldi, Armen M.; Brook, Christopher S.; Mcbriar, Mark D.; Moser, William H.; Sobukawa, Masao; Zhuang, Linghang. Spongistatin synthetic studies. 3. Construction of the C(1-17) spiroketal. Tetrahedron Letters (1997), 38(50), 8675-8678. |
| 349. | Smith, Amos B., III; Zhuang, Linghang; Brook, Christopher S.; Lin, Qiyan; Moser, William H.; Trout, Robert E. Lee; Boldi, Armen M. Spongistatin synthetic studies. 2. Assembly of the C(18-28) spiroketal. Tetrahedron Letters (1997), 38(50), 8671-8674. |
| 348. | Smith, Amos B., III; Zhuang, Linghang; Brook, Christopher S.; Boldi, Armen M.; Mcbriar, Mark D.; Moser, William H.; Murase, Noriaki; Nakayama, Kiyoshi; Verhoest, Patrick R.; Lin, Qiyan. Spongistatin synthetic studies. 1. Construction of a C(29-48) subtarget. Tetrahedron Letters (1997), 38(50), 8667-8670. |
| 347. | Sunazuka, Toshiaki; Hirose, Tomoyasu; Harigaya, Yoshihiro; Takamatsu, Satoshi; Hayashi, Masahiko; Komiyama, Kanki; Omura, Satoshi; Sprengeler, Paul A.; Smith, Amos B., III. Relative and Absolute Stereochemistries and Total Synthesis of (+)-Macrosphelides A and B, Potent, Orally Bioavailable Inhibitors of Cell-Cell Adhesion. Journal of the American Chemical Society (1997), 119(42), 10247-10248. |
| 346. | K.Chen, C.S. Brook, and A.B. Smith, III. 6-7-Dihydrocyclopenta-1,3-dioxin-5(4H)-one. Org. Syn. 1997, 75, 189-194 |
| 345. | A.B. Smith, III, K.M. Yager, B.W. Phillips, and C.M. Taylor. Enantiospecific Synthesis of Diethyl (R)-(-)-(1-Amino-3-methylbutyl) Phosphonate. Org. Syn. 1997, 75, 19-30 |
| 344. | Hirschmann, Ralph; Yager, Kraig M.; Taylor, Carol M.; Witherington, Jason; Sprengeler, Paul A.; Phillips, Barton W.; Moore, William; Smith, Amos B., III. Phosphonate Diester and Phosphonamide Synthesis. Reaction Coordinate Analysis by 31P NMR Spectroscopy: Identification of Pyrophosphonate Anhydrides and Highly Reactive Phosphonylammonium Salts. Journal of the American Chemical Society (1997), 119(35), 8177-8190. |
| 343. | R. Obata, T. Sunazuka, Z. Tian, H. Tomoda, Y. Harigaya, S. Ōmura and A. B. Smith, III. New Analogs of the Pyripyropene Family of ACAT Inhibitors via α-Pyrone Fragmentation and γ-AcylationI Cyclization. Chem. Lett. 1997, 935-936. |
| 342. | Smith, Amos B., III; Hartz, Richard A.; Spoors, P. Grant; Rainier, Jon D. Tremorgenic indole alkaloids. 10. An improved asymmetric synthesis of a tricyclic common intermediate. Israel Journal of Chemistry (1997), 37(1), 69-80. |
| 341. | Smith, Amos B., III; Hirschmann, Ralph; Pasternak, Alexander; Yao, Wenquing; Sprengeler, Paul A.; Holloway, M. Katharine; Kuo, Lawrence C.; Chen, Zhongguo; Darke, Paul L.; Schleif, William A. An Orally Bioavailable Pyrrolinone Inhibitor of HIV-1 Protease: Computational Analysis and X-ray Crystal Structure of the Enzyme Complex. Journal of Medicinal Chemistry (1997), 40(16), 2440-2444. |
| 340. | Smith, Amos B., III; Boldi, Armen M. Multicomponent Linchpin Couplings of Silyl Dithianes via Solvent-Controlled Brook Rearrangement. Journal of the American Chemical Society (1997), 119(29), 6925-6926. |
| 339. | Smith, Amos B., III; Benowitz, Andrew B.; Favor, David A.; Sprengeler, Paul A.; Hirschmann, Ralph. A second-generation synthesis of scalemic 3,5,5-trisubstituted pyrrolin-4-ones: incorporation of functionalized amino acid side-chains. Tetrahedron Letters (1997), 38(22), 3809-3812. |
| 338. | Edwards, Ann M.; Chupa, Janine A.; Strongin, Robert M.; Smith, Amos B., III; Blasie, J. Kent; Bean, John C. Vectorially-Oriented Monolayers of Cytochrome Oxidase: Fabrication and Profile Structures. Langmuir (1997), 13(6), 1634-1643. |
| 337. | Smith, Amos B., III; Condon, Stephen M.; McCauley, John A.; Leazer, Johnnie L., Jr.; Leahy, James W.; Maleczka, Robert E. A Unified Total Synthesis of the Immunomodulators (-)-Rapamycin and (-)-27-Demethoxyrapamycin: Assembly of the Common C(1-20) Perimeter and Final Elaboration. Journal of the American Chemical Society (1997), 119(5), 962-973. |
| 336. | Smith, Amos B., III; Condon, Stephen M.; McCauley, John A.; Leazer, Johnnie L., Jr.; Leahy, James W.; Maleczka, Robert E. A Unified Total Synthesis of the Immunomodulators (-)-Rapamycin and (-)-27-Demethoxyrapamycin: Construction of the C(21-42) Perimeters. Journal of the American Chemical Society (1997), 119(5), 947-961. |
| 335. | Smithrud, David B.; Benkovic, Patricia A.; Benkovic, Stephen J.; Taylor, Carol M.; Yager, Kraig M.; Witherington, Jason; Philips, Barton W.; Sprengeler, Paul A.; Smith, Amos B., III; Hirschmann, Ralph. Investigations of an Antibody Ligase. Journal of the American Chemical Society (1997), 119(2), 278-282. |
| 1996 | |
|---|---|
| 334. | Lundin, A.; Soldatov, A.; Sundqvist, B.; Strongin, R. M.; Brard, L.; Fischer, J. E.; Smith, A. B., III. Compressibility of C61D2 up to 1 GPa in the temperature range 175-345 K. Carbon (1996), 34(9), 1119-1121. |
| 333. | Smith, Amos B., III; Ott, Gregory R. Total Synthesis of (-)-Macrolactin A. Journal of the American Chemical Society (1996), 118(51), 13095-13096. |
| 332. | Gouda, Hiroaki; Matsuzaki, Keiichi; Tanaka, Haruo; Hirono, Shuichi; Omura, Satoshi; McCauley, John A.; Sprengeler, Paul A.; Furst, George T.; Smith, Amos B., III. Stereostructure of (-)-Chloropeptin I, a Novel Inhibitor of gp120-CD4 Binding, via High-Temperature Molecular Dynamics, Monte Carlo Conformational Searching, and NMR Spectroscopy. Journal of the American Chemical Society (1996), 118(51), 13087-13088. |
| 331. | Prokop, Lisa A.; Strongin, Robert M.; Smith, Amos B., III; Blasie, J. Kent; Peticolas, Lawrence J.; Bean, John C. Vectorially oriented monolayers of detergent-solubilized Ca2+-ATPase from sarcoplasmic reticulum. Biophysical Journal (1996), 70(5), 2131-43. |
| 330. | Smith, Amos B., III; Kinsho, Takeshi. Biomimetic total synthesis of the ACAT inhibitor (+)-pyripyropene E. Tetrahedron Letters (1996), 37(36), 6461-6464. |
| 329. | Smith, Amos B., III; Barbosa, Joseph; Wong, Weichyun; Wood, John L. Total Syntheses of (+)-Trienomycins A and F via a Unified Strategy. Journal of the American Chemical Society (1996), 118(35), 8316-8328. |
| 328. | Smith, Amos B., III; Wood, John L.; Wong, Weichyun; Gould, Alexandra E.; Rizzo, Carmelo J.; Barbosa, Joseph; Funayama, Shinji; Komiyama, Kanki; Omura, Satoshi. (+)-Trienomycins A, B, C, and F and (+)-Mycotrienins I and II: Relative and Absolute Stereochemistry. Journal of the American Chemical Society (1996), 118(35), 8308-8315. |
| 327. | Meingast, C.; Roth, G.; Pintschovius, L.; Michel, R. H.; Stoermer, C.; Kappes, M. M.; Heiny, P. A.; Brard, L.; Strongin, R. M.; Smith, A. B., III. Structure, dynamics, and phase transitions in the fullerene derivatives C60O and C61H2. Physical Review B: Condensed Matter (1996), 54(1), 124-131. |
| 326. | Hirschmann, Ralph; Yao, Wenqing; Arison, Byron; Maechler, Laurie; Rosegay, Avery; Sprengeler, Paul A.; Smith, Amos B., III. The first synthesis of a tricyclic homodetic peptide employing coordinated orthogonal protection. Tetrahedron Letters (1996), 37(32), 5637-5640. |
| 325. | Hirschmann, Ralph; Yao, Wenqing; Cascieri, Margaret A.; Strader, Catherine D.; Maechler, Laurie; Cichy-Knight, Maria A.; Hynes, John, Jr.; van Rijn, Rachel D.; Sprengeler, Paul A.; Smith, Amos B., III. Synthesis of Potent Cyclic Hexapeptide NK-1 Antagonists. Use of a Minilibrary in Transforming a Peptidal Somatostatin Receptor Ligand into an NK-1 Receptor Ligand via a Polyvalent Peptidomimetic. Journal of Medicinal Chemistry (1996), 39(13), 2441-2448. |
| 324. | Smith, Amos B., III; Knight, Steven D.; Sprengeler, Paul A.; Hirschmann, Ralph. The design and synthesis of 2,5-linked pyrrolinones. A potential non-peptide peptidomimetic scaffold. Bioorganic & Medicinal Chemistry (1996), 4(7), 1021-1034. |
| 323. | Nagamitsu, Tohru; Sunazuka, Toshiaki; Tanaka, Haruo; Omura, Satoshi; Sprengeler, Paul A.; Smith, Amos B., III. Total Synthesis of (+)-Lactacystin. Journal of the American Chemical Society (1996), 118(15), 3584-90. |
| 323. | Nagamitsu, Tohru; Sunazuka, Toshiaki; Tanaka, Haruo; Omura, Satoshi; Sprengeler, Paul A.; Smith, Amos B., III. Total Synthesis of (+)-Lactacystin. Journal of the American Chemical Society (1996), 118(15), 3584-90. |
| 322. | Smith, Amos B., III; Tokuyama, Hidetoshi. Nitrene additions to [60]fullerene do not generate [6,5]aziridines. Tetrahedron (1996), 52(14), 5257-62. |
| 1995 | |
|---|---|
| 321. | Smith, Amos B., III; Strongin, Robert M.; Brard, Laurent; Furst, George T.; Atkins, Joshua H.; Romanow, William J.; Saunders, Martin; Jimenez-Vazquez, Hugo A.; Owens, Kevin G.; Goldschmidt, Robert J. Synthesis and Characterization of the First C70O Epoxides. Utilization of 3He NMR in Analysis of Fullerene Derivatives. Journal of Organic Chemistry (1996), 61(6), 1904-5. |
| 320. | H. Tomoda, H. Nishida, N. Tabata, T. Sunazuka, A. B. Smith, III, J. Bordner, and S. Omura, “Studies on Pyripyronenes: Potent ACAT Inhibitors Produced by Aspergillus Fumigatus FO-1289,” Tennen Yuki Kagobutsu Toronkai Koen Yoshishu (1995), 37th, 277-282. |
| 319. | Kniaz, K.; Fischer, J. E.; Girifalco, L. A.; McGhie, A. R.; Strongin, R. M.; Smith, A. B., III. Fullerene alloys. Solid State Communications (1995), 96(10), 739-43. |
| 318. | G. Epple, J.R. Mason, E. Aronov, D.L. Nolte, R.A. Hartz, R. Kalostian, D.L. Campbell, and A.B. Smith, III. Feeding Responses to Predator-Based Repellents in the Mountain Beaver (Aplodontia rufa). Ecol. Appl., 1995, 5 1163-1170. |
| 317. | Neumann, D. A.; Huang, Q.; Copley, J. R. D.; Fischer, J. E.; Heiney, P. A.; Strongin, R. M.; Brard, L.; Smith, Amos B., III. A neutron diffraction study of the 6,5-annulene isomer of C61D2. Proceedings – Electrochemical Society (1995), 95-10 (Proceedings of the Symposium on Recent Advances in the Chemistry and Physics of Fullerenes and Related Materials, 1995), 791-7. |
| 316. | Meingast, C.; Roth, G.; Kappes, M. M.; Michel, R. H.; Stoermer, C.; Brard, L.; Heiney, P. A.; Fischer, J. E.; Smith, A. B. III; Strongin, R. M. Orientational glass transitions in the fullerene derivatives C60O and C61H2. Physics and Chemistry of Fullerenes and Derivatives, Proceedings of the International Winterschool on Electronic Properties of Novel Materials, Kirchberg, Austria, Mar. 5-12, 1995 (1995), 167-70. |
| 315. | Nagamitsu, Tohru; Sunazuka, Toshiaki; Obata, Rika; Tomoda, Hiroshi; Tanaka, Haruo; Harigaya, Yoshihiro; Omura, Satoshi; Smith, Amos B., III. Total Synthesis of (+)-Pyripyropene A, a Potent, Orally Bioavailable Inhibitor of Acyl-CoA:Cholesterol Acyltransferase. Journal of Organic Chemistry (1995), 60(25), 8126-7. |
| 314. | Smith, Amos B., III; Chen, Sean S.-Y.; Nelson, Frances C.; Reichert, Janice M.; Salvatore, Brian A. Total Syntheses of (+)-Acutiphycin and (+)-trans-20,21-Didehydroacutiphycin. Journal of the American Chemical Society (1995), 117(48), 12013-14. |
| 313. | Smith, Amos B., III; Qiu, Yuping; Jones, David R.; Kobayashi, Kaoru. Total Synthesis of (-)-Discodermolide. Journal of the American Chemical Society (1995), 117(48), 12011-12. |
| 312. | Smith, Amos B., III; Nolen, Ernest G.; Shirai, Ryuichi; Blase, Frances R.; Ohta, Mitsuaki; Chida, Noritaka; Hartz, Richard A.; Fitch, Duke M.; Clark, William M.; Sprengeler, Paul A. Tremorgenic Indole Alkaloids. 9. Asymmetric construction of an Advanced F-G-H-ring Lactone precursor for the Synthesis of Penitrem D. Journal of Organic Chemistry (1995), 60(24), 7837-48. |
| 311. | Smith, Amos B,. III; Hirschmann, Ralph; Pasternak, Alexander; Guzman, Mark C.; Yokoyama, Akihisa; Sprengeler, Paul A.; Darke, Paul L.; Emini, Emilio A.; Schleif, William A. Pyrrolinone-Based HIV Protease Inhibitors. Design, Synthesis, and Antiviral Activity: Evidence for Improved Transport. Journal of the American Chemical Society (1995), 117(45), 11113-23. |
| 310. | Smith, Amos B., III; Yager, Kraig M.; Taylor, Carol M. Enantioselective Synthesis of Diverse alpha-Amino Phosphonate Diesters. Journal of the American Chemical Society (1995), 117(44), 10879-88. |
| 309. | Smith, Amos B., III; Barbosa, Joseph; Wong, Weichyun; Wood, John L. Total Synthesis of (+)-Trienomycins A and F. Journal of the American Chemical Society (1995), 117(43), 10777-8. |
| 308. | Smith, Amos B., III; Sestelo, Jose Perez; Dormer, Peter G. Total Synthesis of (-)-Furaquinocin C. Journal of the American Chemical Society (1995), 117(43), 10755-6. |
| 307. | Maliszewskyj, Nicholas C.; Josefowicz, Jack Y.; Heiney, Paul A.; McCauley, John P., Jr.; Smith, Amos B., III. Using atomic force microscopy to image Langmuir Blodgett films of disk shaped molecules. Materials Research Society Symposium Proceedings (1995), 355 (Evolution of Thin Film and Surface Structure and Morphology), 147-52. |
| 306. | Smith, Amos B., III; Tokuyama, Hidetoshi; Strongin, Robert M.; Furst, George T.; Romanow, William J.; Chait, Brian T.; Mirza, Urooj A.; Haller, Ivan. Synthesis of oxo- and methylene-bridged C60 dimers, the first well-characterized species containing fullerene-fullerene bonds. Journal of the American Chemical Society (1995), 117(36), 9359-60. |
| 305. | Dinnebier, Robert E.; Stephens, Peter; Carter, Jerry K.; Lommen, Andrea N.; Heiney, Paul A.; McGhie, Andrew R.; Brard, Laurent; Smith, Amos B., III. X-ray powder diffraction structure of triclinic C60Br24(Br2)2. Journal of Applied Crystallography (1995), 28(3), 327-34. |
| 304. | Hirschmann, Ralph; Yager, Kraig M.; Taylor, Carol M.; Moore, William; Sprengeler, Paul A.; Witherington, Jason; Phillips, Barton W.; Smith, Amos B.. III. Phosphonyltriethylammonium Salts: Novel Reactive Species for the Synthesis of Phosphonate Esters and Phosphonamides. Journal of the American Chemical Society (1995), 117(23), 6370-1. |
| 303. | Hirschmann, Ralph; Hynes, John, Jr.; Spoors, P. Grant; Smith, Amos B., III. Chemoselective monoalkylation of 5-(trifluoroacetamido)- and 5-acetamido-1-pentanol derivatives via N,O-bisdeprotonation. Quantitation of evolved H2 as a probe of anion formation. Tetrahedron Letters (1995), 36(14), 2373-6. |
| 302. | Neumann, D. A.; Fischer, J. E.; Copley, J. R. D.; Heiney, P. A.; Rusn, J. J.; Strongin, R. M.; Brard, L.; Smith, Amos B., III. Neutron scattering studies of C61H2. Materials Research Society Symposium Proceedings (1995), 359(Science and Technology of Fullerene Materials), 537-42. |
| 301. | Smith, Amos B., III; Strongin, Robert M.; Brard, Laurent; Furst, George T.; Romanow, William J.; Owens, Kevin G.; Goldschmidt, Robert J.; King, Richard C. Synthesis of Prototypical Fullerene Cyclopropanes and Annulenes. Isomer Differentiation via NMR and UV Spectroscopy. Journal of the American Chemical Society (1995), 117(20), 5492-502. |
| 300. | Iwashima, Makoto; Kinsho, Takeshi; Smith, Amos B. III. A caveat on the Sharpless asymmetric dihydroxylation. Tetrahedron Letters (1995), 36(13), 2199-202. |
| 299. | Smith, Amos B., III; Condon, Stephen M.; McCauley, John A.; Leazer, Johnnie L., Jr.; Leahy, James W.; Maleczka, Robert E., Jr. Total Synthesis of Rapamycin and Demethoxyrapamycin. Journal of the American Chemical Society (1995), 117(19), 5407-8. |
| 298. | Davidson, Patrick; Clerc, Marianne; Ghosh, Surya S.; Maliszewskyj, Nicholas C.; Heiney, Paul A.; Hynes, John, Jr.; Smith, Amos B., III. Diffuse x-ray scattering from freely suspended strands of a discotic liquid crystal. Journal de Physique II (1995), 5(2), 249-52. |
| 297. | Stull, Terrence L.; Hyun, Lisa; Sharetzky, Christine; Wooten, James; McCauley, John P., Jr.; Smith, Amos B., III. Production and oxidation of indole by Haemophilus influenzae. Journal of Biological Chemistry (1995), 270(1), 5-8. |
| 296. | Smith, III, Amos B.; Akaishi, Ryouichi; Jones, David R.; Keenan, Terence P.; Guzman, Mark C.; Holcomb, Ryan C.; Sprengeler, Paul A.; Wood, John L.; Hirschmann, Ralph; Holloway, M. Katharine. Design and synthesis of nonpeptide peptidomimetic inhibitors of renin. Biopolymers (1995), 37(1), 29-53. |
| 1994 | |
|---|---|
| 295. | Hirschmann, R.; Smith, A. B.; Sprengeler, P. A. Some interactions of macromolecules with low molecular weight ligands. Recent advances in peptidomimetic research. New Perspectives in Drug Design, [based on the Proceedings of the International Round Table of the Rhone-Poulenc Rorer Foundation], 9th, Turnberry, UK, Apr., 1994 (1995), Meeting Date 1994, 1-14. |
| 294. | Tomoda, Hiroshi; Nishida, Hiroyuki; Kim, Young Kook; Obata, Rika; Sunazuka, Toshiaki; Omura, Satoshi; Bordner, Jon; Guadliana, Mark; Dormer, Peter G.; Smith, Amos B., III. Relative and Absolute Stereochemistry of Pyripyropene A, A Potent, Bioavailable Inhibitor of Acyl-CoA:Cholesterol Acyltransferase (ACAT). Journal of the American Chemical Society (1994), 116 (26), 12097-8. |
| 293. | Smith, Amos B., III; Pasternak, Alexander; Yokoyama, Akihisa; Hirschmann, Ralph. Enantioretentive alkylation of oxazolidinone aluminum enolates with epoxides: preparation of uncoded homoserine analogs. Tetrahedron Letters (1994), 35(48), 8977-80. |
| 292. | Scott, Lawrence T.; Cooney, Mark J.; Otte, Carola; Puls, Carsten; Haumann, Thomas; Boese, Roland; Smith, Amos B., III; Carroll, Patrick J.; de Meijere, Armin. Enhancement of Through-Space and Through-Bond p-Orbital Interactions. Syntheses and Properties of Permethylated and Perspirocyclopropanated Cyclotetradeca-1,3,6,9,12-pentayne. Journal of the American Chemical Society (1994), 116 (22), 10275-83. |
| 291. | Smith, Amos B., III; Wood, John L.; Keenan, Terence P.; Liverton, Nigel; Visnick, Melean. General Photoisomerization Approach to trans-Benzobicyclo[5.1.0]octenes: Synthetic and Mechanistic Studies. Journal of Organic Chemistry (1994), 59 (22), 6652-66 |
| 290. | Smith, Amos B., III; Strongin, Robert M.; Brard, Laurent; Romanow, William J.; Saunders, Martin; Jimenez-Vazquez, Hugo A.; Cross, R. James. Synthesis and 3He NMR Studies of C60 and C70 Epoxide, Cyclopropane, and Annulene Derivatives Containing Endohedral Helium. Journal of the American Chemical Society (1994), 116 (23), 10831-2. |
| 289. | Zero-field mSR in crystalline C60. Duty, T. L.; Brewer, J. H.; Chow, K.; Kiefl, R. F.; Macfarlane, A. W.; Morris, G. D.; Schneider, J. W.; Hitti, B.; Lichti, R.; et al. TRIUMF, Vancouver, BC, Can. Hyperfine Interactions (1994), 86 (1-4), 789-95. |
| 288. | Yager, Kraig M.; Taylor, Carol M.; Smith, Amos B., III. Asymmetric Synthesis of alpha-Aminophosphonates via Diastereoselective Addition of Lithium Diethyl Phosphite to Chelating Imines. Journal of the American Chemical Society (1994), 116 (20), 9377-8. |
| 287. | G. Cardini, R. Bini, P. R. Salvi, V. Schettino, M. L. Klein, R. M. Strongin, L. Brard, and A. B. Smith. III. Infrared Spectrum of Two Fullerene Derivatives: C60O and C61H2. J. Phys. Chem. 1994, 98, 9966-9971. |
| 286. | A. B. Smith, III, M. C. Guzman, P. A. Sprengeler, T. P. Keenan, R. C. Holcomb, J. L. Wood, P. J. Carroll, and R. Hirschmann. De Novo Design, Synthesis, and X-ray Crystal Structures of Pyrrolinone-Based β-Strand Peptidomimetics. J. Am. Chem. Soc. 1994, 116, 9947-9962. |
| 285. | A. B. Smith, III, R. M. Strongin, L. Brard, G. T. Furst, W. J. Romanow, K. G. Owens, and R. J. Goldschmidt. C71H2 Cyclopropanes and Annulenes: Synthesis and Characterization. J. Chem. Soc., Chem. Commun. 1994, 2187-2188. |
| 284. | A. B. Smith, III, C. Taylor, S. J. Benkovic, and R. Hirschmann. Peptide Bond Formation Via Catalytic Antibodies: Synthesis of a Novel Phosphonate Diester Hapten. Tetrahedron. Lett. 1994, 35, 6853-6856. |
| 283. | A. B. Smith, III, and M. Iwashima. Calyculin Synthetic Studies. 4. Remarkable Reversal of Diastereoselectivity in Payne Epoxidation of Vinyl Spiroketal Intermediates. Tetrahedron Lett. 1994, 35, 6051-6052. |
| 282. | J. A. Chupa, J. P. McCauley, Jr., R. M. Strongin, A. B. Smith, III, J. K. Blasie, L. J. Peticolas, and J. C. Bean. Vectorially Oriented Membrane Protein Monolayers: Profile Structures via X-Ray Interferometry/Molography. Biophysical Journal 1994, 67, 336-348. |
| 281. | A. B. Smith, III, R. E. Maleczka, Jr., J. L. Leazer, Jr., J. W. Leahy, J. A. McCauley, and S. M. Condon. Rapamycin Synthetic Studies. 2. Elaboration of the C(10)-C(26) Perimeter. Tetrahedron Lett. 1994, 35, 4911-4914. |
| 280. | A. B. Smith, III, S. M. Condon, J. A. McCauley, J. W. Leahy, J. L. Leazer, Jr., and R. E. Maleczka, Jr. Rapamycin Synthetic Studies. 1. Construction of the C(27)-C(42) Subunit. Tetrahedron Lett. 1994, 35, 4907-4910. |
| 279. | H.-G. Knaus, O. B. McManus, S. H. Lee, W. A. Schmalhofer, M. Garcia-Calvo, L. Helms, M. Sanchez, K. Giangiacomo, J. P. Reuben, A. B. Smith, III, G. J, Kaczorowski, and M. L. Garcia. Tremorgenic Indole Alkaloids Potently Inhibit Smooth Muscle High-Conductance Calcium-Activated Potassium Channels. Biochemistry 1994, 33, 5819-5828. |
| 278. | W. A. MacFarlane, R. F. Kiefl, K. Chow, S. Dunsiger, T. L. Duty, T. M. S. Johnston, J. W. Schneider, J. Sonier, L. Brard, R. M. Strongin, J. E. Fischer, and A. B. Smith, III. Hebel-Slichter Peak and Superconducting Energy Gap in Rb3C60 Observed by Muon Spin Relaxation. Hyperfine Interactions 1994, 86, 467. |
| 277. | D. Reznik, W. A. Kamitakahara, D. A. Neumann, J. R. D. Copley, J. E. Fischer, R. M. Strongin, M. A. Cichy, and A. B. Smith, III. A Neutron Scattering Study of Librations and Intramolecular Phonons in Rb2.6K0.4C60. Phys. Rev. B 1994, 49, 1005-1010. |
| 276. | R. Hirschmann, A. B. Smith, III, C. M. Taylor, P. A. Benkovic, S. D. Taylor, K. M. Yager, P. A. Sprengeler, and S. Benkovic. Peptide Syntheses Catalyzed by an Antibody Containing a Binding Site for Variable Amino Acids. Science 1994, 265, 234-237. |
| 275. | A. B. Smith, III, K. Chen, D. J. Robinson, L. M. Laakso, and K. J. Hale. Formal Total Synthesis of FK506. Concise Construction of the C(10)-C(34) Segment Via an Effective Coupling Tactic. Tetrahedron Lett. 1994, 35, 4271-4274. |
| 274. | A. N. Lommen, P. A. Heiney, G. B. M. Vaughan, P. W. Stephens, D. Liu, D. Li, A. L. Smith, A. R. McGhie, R. M. Strongin, L. Brard, and A. B. Smith, III. Structure and phase transition of the 6,5-annulene isomer of C61H2. Phys. Rev. B. 1994, 49, 12572-12577. |
| 273. | H. Selig, K. Kniaz, G. B. M. Vaughan, J. E. Fischer, and A. B. Smith, III. Fluorinated Fullerenes: Synthesis and Characterization. Mikromolekular Chemie, Section Macromolecular Symposia 1994, 82, 89-98. |
| 272. | T. Sunazuka, R. Obata, L. Zhuorong, S. Takamatsu, K. Komiyama, S. Ōmura, and A. B. Smith, III. Relative and Absolute Stereochemistry of the Melanogenesis Inhibitors OH-3984 K1 and K2. Partial Synthesis from Albocycline. Tetrahedron Lett. 1994, 35, 2635-2636. |
| 271. | N. C. Maliszewskyj, P. A. Heiney, J, Y. Josefowicz, J. P. McCauley, Jr., and A. B. Smith, III. Unexpected Square Symmetry Seen by Atomic Force Microscopy in Bilayer Films of Disklike Molecules. Science 1994, 26477-79. |
| 270. | D. M. Cox, S. D. Cameron, A. Tuinman, A. Gakh, J. L. Adcock, R. N. Compton, E. W. Hagaman, K. Kniaz, J. E. Fischer, R. M. Strongin, M. A. Cichy, and A. B. Smith, III. X-ray Photoelectron and NMR Studies of Polyfluorinated C60: Evidence that C-C Bonds are Broken. J. Am. Chem. Soc. 1994, 116, 1115-1120. |
| 269. | B. A. Salvatore and A. B. Smith, III. Calyculin Synthetic Studies. 3. Enantiomeric Purity Determination for The C(26)-C(32) Oxazole Segment via the Silks-Odom 77Se NMR Method. Tetrahedron Lett. 1994, 35, 1329-1330. |
| 268. | A. B. Smith, III, R. Hirschmann, A. Pasternak, R. Akaishi, M. C. Guzman, D. R. Jones, T. P. Keenan, P. A. Sprengeler, P. L. Darke, E. A. Emini, M. K. Holloway, and W. A. Schleif. Design and Synthesis of Peptidomimetic Inhibitors of HIV-1 Protease and Renin. Evidence for Improved Transport. J. Med. Chem. 1994, 37, 215-218. |
| 1993 | |
|---|---|
| 267. | G. B. M. Vaughan, P. A. Heiney, D. E. Cox, J. E. Fischer, A. R. McGhie, A. L. Smith, R. M. Strongin, M. A. Cichy, and A. B. Smith, III. Structural Phase Transitions and Orientation Ordering in C70. Chem. Phys. 1993, 178, 599-613. |
| 266. | T. Sunazuka, S. Ōmura, T. Nagamitsu, K. Matsuzaki, H. Tanaka, and A. B. Smith, III. Total Synthesis of (+)-Lactacystin, the First Non-Protein Neurotropic Factor. Tennen Yuki Kagobutsu Toronkai Koen Yoshishu, 1993, 35th, 72-79. |
| 265. | R. Tycko, G. Dabbagh, G. B. M. Vaughan, P. A. Heiney, R. M. Strongin, M. A. Cichy, and A. B. Smith, III. Molecular orientational dynamics in solid C70: Investigation by one- and two-dimensional magic angle spinning nuclear magnetic resonance. J. Chem. Phys. 1993, 99,7554-7564. |
| 264. | R. Hirschmann, K. C. Nicolaou, S. Pietranico, E. M. Leahy, J. Salvino, B. Arison, M. A. Cichy, P. G. Spoors, W. C. Shakespeare, P. A. Sprengeler, P. Hamley, A. B. Smith, III, T. Reisine, K. Raynor, L. Maechler, C. Donaldson, W. Vale, R. M. Freidinger, M. R. Cascieri, and C. D. Strader. De Novo Design and Synthesis of Somatostatin Non-Peptide Peptidomimetics Utilising β-D-Glucose as a Novel Scaffolding. J. Am. Chem. Soc. 1993, 115, 12550-12568. |
| 263. | S. K. Chowdhury, S. Cameron, D. M. Cox, K. Kniaz, R. M. Strongin, M. A. Cichy, J. E. Fischer, and A. B. Smith, III. Mass Spectrometric Investigation of Polyfluorinated C60. Evidence for the Existence of C60F2n (n = 0 – 30). Org. Mass Spec. 1993, 28, 860-866. |
| 262. | J. E. Fischer, D. E. Luzzi, K. Kniaz, A. R. McGhie, D. A. Ricketts-Foot, W. R. Romanow, G. B. M. Vaughan, P. A. Heiney, D. Li, A. L. Smith, R. M. Strongin, M. A. Cichy, L. Brard, and A. B. Smith, III. Existence of high-order superlattices in orientationally-ordered solid C60. Phys. Rev. B 1993, 47, 14614-14617. |
| 261. | K. Shimokawa and A. B. Smith, III. Total Synthesis of The Pollen-Growth Inhibitor (–)-Emeniveol. Assignment of Absolute Stereochemistry. Tetrahedron Lett. 1993, 34, 7383-7384. |
| 260. | T. Sunazuka, N. Tabata, T. Nagamitsu, H. Tomoda, S. Ōmura, and A. B. Smith, III. Asymmetric Synthesis of the Anticoccidial Antibiotic Diolmycin A1. Determination of Absolute Stereochemistry. Tetrahedron Lett. 1993, 34, 6659-6660. |
| 259. | T. Yildirim, J. E. Fischer, A. B. Harris, P. W. Stephens, D. Liu, L. Brard, R. M. Strongin, and A. B. Smith, III. Orientational Phase Transition in NaxC60 (1 < x < 3). Phys. Rev. Lett. 1993, 71, 1383-1386. |
| 258. | A. Lender, W. Yao, R. A. Spanevello, G. Furst, P. A. Sprengeler, R. Hirschmann, and A. B. Smith, III. Design and synthesis of sulfur-free cyclic hexapeptides which contain the RGD sequence and bind to the fibrinogen GP IIb/IIIa receptor. Int. J. Peptide Protein Res. 1993, 42, 509-517. |
| 257. | S. H. J. Idziak, P. A. Heiney, J. P. McCauley, Jr., P. Carroll, and A. B. Smith, III. Phase Diagram of Hexa-N-alkylthiotriphenylenes. Mol. Cryst. Liq. Cryst. Lett. 1993, 237, 271-275. |
| 256. | T. Sunazuka, T. Nagamitsu, H. Tanaka, S. Ōmura, P. A. Sprengeler, and A. B. Smith, III. An Efficient Asymmetic Synthesis of the Four Stereoisomers of 3-Hydroxyleucine. Tetrahedron Lett. 1993, 34, 4447-4448. |
| 255. | K. Kniaz, J. E. Fischer, H. Selig, G. B. M. Vaughan, W. J. Romanov, D. M. Cox, S. K. Choudhury, J. P. McCauley, Jr., R. M. Strongin, and A. B. Smith, III. Fluorinated Fullerenes: Synthesis, Structure and Properties. J. Am. Chem. Soc. 1993, 115, 6060-6064. |
| 254. | J. J.-W. Duan and A. B. Smith, III. Iodine Monobromide (IBr) at Low Temperature: Enhanced Diastereoselectivity in Electrophilic Cyclizations of Homoallylic Carbonates. J. Org. Chem. 1993, 58, 3703-3711. |
| 253. | N. C. Maliszewskyj, P. A. Heiney, D. R. Jones, R. M. Strongin, M. A. Cichy, and A. B. Smith, III. Langmuir Films of C60, C60O, and C61H2. Langmuir 1993, 9, 1439-1441. |
| 252. | R. F. Kiefl, W. A. MacFarlane, K. H. Chow, S. Dunsiger, T. L. Duty, T. M. S. Johnston, J. W. Schneider, J. Sonier, L. Brard, R. M. Strongin, J. E. Fischer, and A. B. Smith, III. Coherence Peak and Superconducting Energy Gap in Rb3C60 Observed by Muon Spin Relaxation. Phys. Rev. Lett. 1993, 70, 3987-3990. |
| 251. | G. Epple, A. M. Belcher, I. Kuderling, U. Zeller, L. Scolnick, K. L. Greenfield and A. B. Smith, III. Making sense out of scents: species differences in scent glandsl scent-marking behaviour and scent-mark composition in the Callitrichidae. In Marmosets and Tamarins: Systematics, Behaviour, and Ecology. A. Rylands (Ed.). Oxford University Press: Oxford, 1993; pp 123-151. |
| 250. | A. B. Smith, III, R. M. Strongin, L. Brard, G. T. Furst, W. J. Romanow, K. G. Owens, and R. C. King. 1,2-Methanobuckminsterfullerene (C61H2), the Parent Fullerene Cyclopropane: Synthesis and Structure. J. Am. Chem. Soc. 1993, 115, 5829-5830. |
| 249. | T. Sunazuka, T. Nagamitsu, K. Matsuzaki, H. Tanaka, S. Ōmura, and A. B. Smith, III. Total Synthesis of (+)-Lactacystin, the First Non-Protein Neurotropic Factor. J. Am. Chem. Soc. 1993, 115, 5302. |
| 248. | Q. Zhu, O. Zhou, J. E. Fischer, A. R. McGhie, W. R. Romanow, R. M. Strongin, M. A. Cichy, and A. B. Smith, III. Unusual thermal stability of a site-ordered MC60 rocksalt structure (M = K, Rb or Cs). Phys. Rev. B 1993, 47, 13948-13951. |
| 247. | R. Hirschmann, P. A. Sprengeler, T. Kawasakil J. W. Leahy, W. C. Shakespeare, and A. B. Smith, III. The Versatile Steroid Nucleus: Design and Synthesis of Peptidomimetic Employing this Novel Scaffold. Tetrahedron Symposium in Print 1993, 49, 3665-3676. |
| 246. | A. B. Smith, III, M. Ohta, W. M. Clark, and J. W. Leahy. An End Game Protocol for the Construction of the G-H-I Rings of Penitrem D, a Tremorgenic lndole Alkaloid. Tetrahedron Lett. 1993, 34, 3033-3036. |
| 245. | J. A. Chupa, S. Xu, R. F. Fischettil R. M. Strongin, J. P. McCauley, Jr, A. B. Smith, III, J. K. Blasie, L. J. Peticolas, and J. C. Bean. A Monolayer of C60 Tethered to the Surface of an Inorganic Substrate: Assembly and Structure. J. Am. Chem. Soc. 1993, 115, 4383-4384. |
| 244. | J. Y. Josefowicz, N. C. Maliszewskyj, S. H. J. ldziak, P. A. Heiney, G. C. Farrington, J. P. McCauley, and A. B. Smith, III. Structure of Langmuir-Blodget Films of Disk-Shaped Molecules Determined by Atomic Force Microscopy. Science 1993, 260, 323. |
| 243. | S. M. Amador, J. M. Pachence, R. Fischetti, J. P. McCauley, Jr., A. B. Smithl III, and J. K. Blasie. Use of Self-Assembled Monolayers To Covalently Tether Protein Monolayers to the Surface of Solid Substrates. Langmuir 1993, 9, 812-817. |
| 242. | S. A. Peak and A. B. Smith, III. Synthetic Routes to the Oxahydrindene Subunit of the Avermectin-Milbemycin Family of Antiparasitic Agents: A Review. In Studies in Natural Products Chemistry. Atta-ur-Rahman (Ed.). Elsevier: New York, 1993; pp 3-33. |
| 241. | A. B. Smith, III, R. C. Holcomb, M. C. Guzman, T. P. Keenan, P. A. Sprengeler, and R. Hirschmann. An Effective Synthesis of Scalemic 3,5,5-Trisubstituted Pyrrolin-4-ones. Tetrahedron Lett. 1993, 34, 63-66. |
| 1992 | |
|---|---|
| 240. | I. Belaish, I. Entin, R. Goffer, D. Davidov, H. Selig, J. P. McCauley, Jr., N. Coustel, J. E. Fischer, and A. B. Smith, III. Spin cast thin films of fullerenes and fluorinated fullerenes: Preparation and characterization by x-ray reflectivity and surface diffuse x-ray scattering. J. Appl. Phys. 1992, 71, 5248-5250. |
| 239. | O. Zhou, Q. Zhu, G. B. M. Vaughan, J. E. Fischer, P. A. Heiney, N. Coustel, J. P. McCauley, Jr., A. B. Smith, III, and D. E. Cox. Temperature Dependent Structural Studies of K- and RB-Doped C60. In Novel Forms of Carbon. C. L. Renchler, J. J. Pouch, and D. M. Cox (Eds.). MRS Symposium Proceedings, 1992; Vol. 270, p 191. |
| 238. | W. A. Kamitakahara, J. R. D. Copley, R. L. Cappelletti, J. J. Rush, D. A. Neumann, J. E. Fischer, J. P. McCauley, Jr., and A. B. Smith, Ill. Rotations, Vibrations and Structure in Solid C60: Investigations by Neutron Scattering. In Novel Forms of Carbon. C. L. Renchler, J. J. Pouch, and D. M. Cox. (Eds.). MRS Symposium Proceedings, 1992; Vol. 270, p 167. |
| 237. | J. K. Blasie, S. Xu, M. Murphy, J. Chupa, J. P. McCauley, A. B. Smith, III, L. J. Petacolas, and J. C. Bean. Profile Structures of Macromolecular Monolayers on Solid Substrates by X-ray lnterferometry/Holography. MRS Symposium Proceedings 1992; Vol. 270, pp 399-409. |
| 236. | T. Yildirim, O. Zhou, J. E. Fischer, N. Bykovetz, R. M. Strongin, M. A. Cichy, A. B, Smith, III, C. L. Lin, and R. Jelinek. Intercalation of Sodium Heteroclusters into the C60 Lattice. Nature 1992, 360, 568-571. |
| 235. | G. B. M. Vaughan, P. A. Heiney, D. E. Cox, A. R. McGhie, D. R. Jones, R. M. Strongin, M. A. Cichy, and A. B. Smith, III. The orientational phase transition in solid buckminsterfullerene epoxide (C60O). Chem. Phys. 1992, 168, 185-193. |
| 234. | A. B. Smith, III, T. P. Keenan, R. C. Holcomb, P. A. Sprengeler, M. C. Guzman, J. L. Wood, P. J. Carroll, and R. Hirschmann. Design, Synthesis, and Crystal Structure of a Pyrrolinone-Based Peptidomimetic Possessing the Conformation of a β-Strand: Potential Application to the Design of Novel Inhibitors of Proteolytic Enzymes. J. Am. Chem. Soc. 1992, 114, 10672-10674. |
| 233. | J. L. Wood and A. B. Smith, III. Synthesis and Rearrangement Reactions of the First trans-Homotropone. J. Am. Chem. Soc. 1992, 114, 10075-10076. |
| 232. | S. C. Graham, K. Pichler, R. H. Friend, W. J. Romanow, J. P. McCauley, Jr., N. Coustel, J. E. Fischer, and A. B. Smith, III. Photoluminescence in solid films of C60. Synthetic Metals 1992, 49-50, 531-535. |
| 231. | R. Hirschmann, P. A. Sprengeler, T. Kawasaki, J. W. Leahy, W. C. Shakespeare, and A. B. Smith, III. The First Design and Synthesis of a Steroidal Peptidomimetic. The Potential Value of Peptidomimetics in Elucidating the Bioactive Conformation of Peptide Ligands, J. Am. Chem Soc. 1992, 114, 9699-9701. |
| 230. | A. B. Smith, III, J. R. Empfield, R. A. Rivero, H. A. Vaccaro, J. J.-W. Duan, and M. M. Sulikowski. Total Synthesis of (±)-Breynolide, an Aglycon Derivative of the Orally Active Hypocholesterolemic Agent Breynin A. J. Am. Chem. Soc. 1992, 114, 9419-9434. |
| 229. | R. Hirschmann, K. C. Nicolaou, S. Pietranico, J. Salvino, E. M. Leahy, P. A. Sprengeler, G. Furst, A. B. Smith, III, C. D. Strader, M. A. Cascieri, M. R. Candelore, C. Donaldson, W. Vale, and L. Maechler. Nonpeptidal Peptidomimetics with a β-D-Glucose Scaffolding. A Partial Somatostatin Agonist Bearing a Close Structural Relationship to a Potent, Selective Substance P Antagonist. J. Am. Chem. Soc. 1992, 114, 9217-9218. |
| 228. | J. J.-W. Duan, P. A. Sprengeler, and A. B. Smith, III. Iodine Monobromide (IBr) at Low Temperature: A Superior Protocol for Diastereoselective Cyclizations of Homoallylic Carbonates. Tetrahedron Lett. 1992, 33, 6439-6442. |
| 227. | J. L. Wood, P. J. Carroll, and A. B. Smith, III. Novel Structures of a trans-Cyclooctene and trans-Fused Cyclopropane Generated via Photoisomerization of a gem-Dichlorocyclopropylbenzocycloheptenone. J. Chem. Soc., Chem. Commun. 1992, 2, 1433. |
| 226. | A. B. Smith, III, T. A. Rano, N. Chida, G. A. Sulikowski, and J. L. Wood. Total Synthesis of Cytotoxic Macrocycle (+) Hitachimycin. [Erratum to J. Am. Chem. Soc. 1992, 114, 8002-8022.] J. Am. Chem. Soc. 1992, 115, 4947. |
| 225. | Smith, Amos B., III; Rano, Thomas A.; Chida, Noritaka; Sulikowski, Gary A.; Wood, John L. Total synthesis of the cytotoxic macrocycle (+)-hitachimycin. Journal of the American Chemical Society (1992), 114 (21), 8008-22. |
| 224. | A. B. Smith, III, J. L. Wood, C. J. Rizzo, G. T. Furst, P. J. Carroll, J. Donohue, and S. Ōmura. (+) Hitachimycin: Stereochemistry and Conformational Analysis. J. Am. Chem. Soc. 1992, 114, 8003-8007. |
| 223. | A. B. Smith, III, T. P. Keenan, R. T. Gallagher, G. T. Furst, and P. G. Dormer. Structures of Breynins A and B, Architecturally Complex, Orally Active Hypocholesterolemic Spiroketal Glycosides. J. Org. Chem. 1992, 57, 5115-5120. |
| 222. | G. B. M. Vaughan, P. A. Heiney, J. P. McCauley, Jr., and A. B. Smith, III. Conductivity and Structure of a Liquid-Crystalline Organic Conductor. Phys. Rev. B 1992,46, 2787-2791. |
| 221. | J. R. D. Copley, D. A. Neumann, R. L. Cappelletti, W. A. Kamitakahara, E. Prince, N. Coustel, J. P. McCauley, Jr., N. C. Maliszewskyj, J. E. Fischer, A. B. Smith, III, K. M. Creegan, and D. M. Cox. Structure and Low Energy Dynamics of Solid C60. Physica B. 1992, 180 & 181, 706-708. |
| 220. | D. A. Neumann, J. R. D. Copley, W. A. Kamitakahara, J. J. Rush, R. L. Cappelletti, N. Coustell J. E. Fischer, J. P. McCauley, Jr., A. B. Smith, III, K. M. Creegan, and D. M. Cox. Rotational Dynamics and Orientational Melting of C60: A Neutron Scattering Study. J. Chem. Phys. 1992, 96, 8631-8633. |
| 219. | M. M. Sulikowski, G. E. R. Ellis Davies and A. B. Smith, III. Avermectin-Milbemycin Synthetic Studies. Part 7. An Approach to the Southern Hemisphere of Milbemycin α1. J. Chem. Soc., Perkin Trans. 1, 1992, 979-989. |
| 218. | P. G. Dormer, A. B. Smith, III, S. Funayama and S. Ōmura. Furaquinocins A-G: Relative and Absolute Stereochemistry. Tetrahedron Lett. 1992, 33, 1717-1720. |
| 217. | R. F. Kiefl, J. W. Schneider, A. MacFarlane, K. Chow, T. L. Duty, T. L. Estle, B. Hitti, R. L. Lichti, E. J. Ansaldo, C. Schwab, P. W. Percival, G. Wei, S. Wlodek, K. Kojima, W. J. Romanow, J. P. McCauley, Jr., N. Coustel, J. E. Fischer, and A. B. Smith, III. Molecular Dynamics of the Muonium-C60 Radical in Solid C60. Phys. Rev. Lett. 1992, 68, 1347-1350. |
| 216. | Smith, Amos B., III; Leahy, James W.; Noda, Ichio; Remiszewski, Stacy W.; Liverton, Nigel J.; Zibuck, Regina. Total synthesis of the latrunculins. Journal of the American Chemical Society (1992), 114 (8), 2995-3007. |
| 215. | A. B. Smith, III, G. A. Sulikowski, M. M. Sulikowski, and K. Fujimoto. Applications of an Asymmetric [2+2]-Photocycloaddition, Total Synthesis of (–)-Echinosporin. Construction of an Advanced 11 Deoxyprostaglandin Intermediate. J. Am. Chem. Soc. 1992, 114, 2567-2576. |
| 214. | P. A. Heiney, G. B. M. Vaughan, J. E. Fischer, N. Coustel, D. Em Cox, J. R. D. Copley, D. A. Neumann, W. A. Kamitakahara, K. M. Creegan, D. M. Cox, J. P. McCauley, Jr., and A. B. Smith, III. Discontinuous volume change at the orientational-ordering transition in solid C60. Phys. Rev. B, Rapid Commun. 1992, 45, 4544-4547. |
| 213. | J. E. Fischer, P. A. Heiney, and A. B. Smith, III, “Solid State Chemistry of Fullerene-Based Materials,” Acc. Chem. Res., 25, 112-118 (1992). |
| 213. | J. E. Fischer, P. A. Heiney, and A. B. Smith, III, “Solid State Chemistry of Fullerene-Based Materials,” Acc. Chem. Res., 25, 112-118 (1992). |
| 212. | S. Fujiwara and A. B. Smith, III. Avermectin-Milbemycin Synthetic Studies. 6. Stereoselective Elaboration of the “Southern Hemisphere” Oxahydrindene. Tetrahedron Lett. 1992, 33, 1185-1188. |
| 211. | A. B. Smith, III, J. Kingery-Wood, T. L. Leenay, E. G. Nolen, and T. Sunazuka. lndole Diterpene Synthetic Studies. 8. Total Synthesis of (+) Paspalicine and (+) Paspalininem. J. Am. Chem. Soc. 1992, 114, 1438-1449. |
| 210. | O. Zhou, G. B. M. Vaughan, Q. Zhu, J, E. Fischer, P. A. Heiney, N. Coustel, J. P. McCauley, Jr., and A. B. Smith, III. Compressibility of M3C60 Fullerene Superconductors: Correlation Between Tc and Lattice Parameter. Science 1992, 255, 833-835. |
| 209. | L. D. Rotter, Z. Schlesinger, J. P. McCauley, Jr., N. Coustel, J. E. Fischer, and A. B. Smith, III. Infrared reflectivity measurements of a superconducting energy scale in Rb3C60. Nature 1992, 355, 532-535. |
| 208. | S. H. J. ldziak, N. C. Maliszewskyj, G. B. M. Vaughan, P. A. Heiney, C. Mertesdorf, H. Ringsdod, J. P. McCauley, Jr. and A. B. Smith, III. Hexagonal Order in Some Mesophases of Hexacyclene Derivatives. J. Chem. Soc., Chem. Commun. 1992, 2, 98-99. |
| 207. | A. B. Smith, III, J. P. McCauley, Jr., and D. R. Jones. Fullerene Oxides and Synthetic Methods Therefore, U.S. Patent (Filed November 19, 1991). |
| 206. | K. M. Creegan, J. L. Robbins, W. K. Robbins, J. M. Millar, R. D. Sherwood, P. J. Tindall, D. M. Cox, A. B. Smith, III, J. P. McCauley, Jr., D. R. Jones, and R. T. Gallagher. Synthesis and Characterization of C60O, the First Fullerene Epoxide. J. Am. Chem. Soc. 1992, 114, 1103-1105. |
| 205. | Y. Chabre, D. Djurado, M. Armand, W. J. Romanow, N. Coustel, J. P. McCauley, Jr., J. E. Fischer, and A. B. Smith, III. Electrochemical Intercalation of Lithium into Solid C60. J. Am. Chem. Soc. 1992, 114, 764-766. |
| 204. | N. C. Maliszewskyj, P. A. Heiney, J. K. Blasie, J. P, McCauley, Jr., and A. B. Smith, III. Self organization of discogenic molecules at the air-water interface. J. Phys. II, France 1992, 2, 75-85. |
| 1991 | |
|---|---|
| 203. | K. Pichler, S. Graham, O. M. Gelsen, R. H. Friend, W. J. Romanow, J. P. McCauley, Jr., N. Coustel, J. E. Fischer, and A. B. Smith, III. Photophysical Properties of Solid Films of Fullerene, C60. J. Phys. Condensed Matter 1991, 9259-9270. |
| 202. | D. A. Neumann, J. R. D. Copley, R. L. Cappelletti, W. A. Kamitakahara, R. M. Lindstrom, K. M. Creegan, D. M. Cox, W. J. Romanow, N. Coustel, J. P. McCauley, Jr., N. C. Maliszewskyj, J. E. Fischer, and A. B. Smith, III. Coherent Quasielastic Neutron Scattering Study of the Rotational Dynamics of C60 in the Orientationally Disordered Phase. Phys. Rev. Lett. 1991, 67, 3808-3811. |
| 201. | A. B. Smith, III, R. T. Gallagher, T. P. Keenan, G. T. Furst, and P. G. Dormer. Structures of Breynins A and B, Architecturally Complex, Hypocholesterolemic Spiroketal Glycosides. A Revised Formulation of Breynin B. Tetrahedron Lett. 1991, 32, 6847-6850. |
| 200. | G. B. M. Vaughan, P. A. Heiney, J. E. Fischer, D. E. Luzzi, D. A. Ricketts-Foot, A. R. McGhie, Y.-W. Hui, A. L. Smith, D. E. Cox, W. J. Romanow, B. H. Allen, N. Coustel, J. P. McCauley, Jr., and A. B. Smith, III. Orientational Disorder in Solvent-Free Solid C70. Science 1991, 254, 1350-1353. |
| 199. | Q. Zhu, O. Zhou, N. Coustel, G. B. M. Vaughan, J. P. McCauley, Jr., W. J. Romanow, J. E. Fischer, and A. B. Smith, III. X-Ray Diffraction Evidence for Nonstoichiometric Rubidium-C60 Intercalation Compounds. Science 1991, 254, 545-548. |
| 198. | J. P. McCauley, Jr., Q. Zhu, N. Coustel, O. Zhou, G. Vaughan, S. H. J. Idziak, J. E. Fischer, S. W. Tozer, D. M. Groski, N. Bykovetz, C. L. Lin, A. R. McGhie, B. H. Allen, W. J. Romanow, A. M. Denenstein, and A. B. Smith, III. Synthesis, Structure, and Superconducting Properties of Single-Phase Rb3C60. A New, Convenient Method for the Preparation of M3C60 Superconductors. J. Am. Chem. Soc. 1991, 113, 8537-8538. |
| 197. | S. H. J. ldziak, N. C. Maliszewskyj, P. A. Heiney, J. P. McCauley, Jr., P. A. Sprengeler, and A. B. Smith, III. Structure and Mesophases of Hexacyclene Derivatives. J. Am. Chem. Soc. 1991, 113, 7666-7672. |
| 196. | A. B. Smith, III, B. A. Salvatore, K. G. Hull, and J. J.-W. Duan. Calyculin Synthetic Studies. 2. Stereocontrolled Assembly of the C(9)-C(13) Dithiane and C(26)-C(37) Oxazole Intermediates. Tetrahedron Lett. 1991, 32, 4859-4862. |
| 195. | A. B. Smith, III, J. J.-W. Duan, K. G. Hull, and B. A. Salvatore. Calyculin Synthetic Studies. Stereoselective Construction of the C(14)-C(25) Spiroketal Subunit. Tetrahedron Lett. 1991, 32, 4855-4858. |
| 194. | R. J. Sension, C. M. Phillips, A. Z. Szarka, W. J. Romanow, A. R. McGhie, J. P. McCauley, Jr., A. B. Smith, III, and R. M. Hochstrasser. Transient Absorption Studies of C60 in Solution. J. Phys. Chem. 1991, 95, 6075-6078. |
| 193. | C. T. Chen, L. H. Tjeng, P. Rudolf, G. Meigs, J. E. Rowe, J. Chen, J. P. McCauley, Jr., A. B. Smith, III, A. R. McGhie, W. J. Romanow, and E. W. Plummer. Electronic states and phases of KxC60 from photoemission and X-ray absorption spectroscopy. Nature 1991,352, 603-605. |
| 192. | H. Selig, C. Lifshitz, T. Peres, J. E. Fischer, A. R. McGhie, W. J. Romanow, J. P. McCauley, Jr., and A. B. Smith, III. Fluorinated Fullerenes. J. Am. Chem. Soc. 1991, 113, 5475-S76. |
| 191. | P. A. Heiney, J. E. Fischer, A. R. McGhie, W. J. Romanow, A. M. Denensteins, J. P. McCauley, Jr., A. B. Smith, III, and D. E. Cox. Orientational Ordering Transition in Solid C60. Phys. Rev. Lett. 1991, 66, 2911-2914. |
| 190. | O. Zhou, J. E. Fischer, N. Coustel, S. Kycia, Q. Zhu, A. R. McGhie, W. J. Romanow, J. P. McCauley, Jr., A. B. Smith, III, and D. E. Cox. Structure and bonding in alkali metal-doped C60. Nature 1991, 351, 462-464. |
| 189. | J. E. Fischer, P. A. Heiney, A. R. McGhie, W. J. Romanow, A. M. Denenstein, J. P. McCauley, Jr. and A. B. Smith, III. Compressibility of Solid C60. Science 1991, 252, 1288-1290. |
| 188. | C. J. Rizzo and A. B. Smith, III. Aphidicolin Synthetic Studies. A Stereocontrolled End Game. J. Chem. Soc., Perkin Trans. 1, 1991, 5, 969-979. |
| 187. | A. B. Smith, III, J. R. Empfield, R. A. Rivero, and H. A. Vaccaro. Total Synthesis of (±) Breynolide: An Aglycon Derivative of a Potent, Orally Active Hypocholesterolemic Agent. J. Am. Chem. Soc. 1991, 113, 4037-4038. |
| 186. | A. B. Smith, III, J. P. Konopelski, B. A. Wexler, and P. A. Sprengeler. Quadrone Structural and Synthetic Studies. Total Synthesis of Natural (–)-Quadrones the (+)-Enantiomer, and the Racemate. Conformational Analysis, Circular Dichroism, and Determination of Absolute Stereochemistry. J. Am. Chem. Soc. 1991, 113, 3533-3542. |
| 185. | W. K. Lee, P. A. Heiney, J. P. McCauley, Jr. and A. B. Smith, III. Fourier Transform Infrared Absorption Study of Hexa(hexylthio)triphenylene: A Discotic Liquid Crystal. Mol. Cryst. Liq. Cryst. 1991, 198, 273-284. |
| 184. | A. B. Smith, III, J. L. Wood, A. E. Gould, S. Ōmura, and K. Komiyama. Isolation and Structure Determination of (+)-Trienomycin F. An Endgame Synthetic Strategy for the Trienomycin Family of Antitumor Antibiotics. Tetrahedron Lett. 1991, 32, 1627-1630. |
| 183. | Smith, Amos B.,III; Hale, Karl J.; Vaccaro, Henry A.; Rivero, Ralph A. Phyllanthoside-phyllanthostatin synthetic studies. 9. Total syntheses of (-)-phyllanthostatin 1, (+)-phyllanthostatin 2, and (+)-phyllanthostatin 3. Journal of the American Chemical Society (1991), 113 (6), 2112-22. |
| 182. | A. B. Smith, III, R. A. Rivero, K, J. Hale, and H. A. Vaccaro. Phyllanthoside-Phyllanthostatin Synthetic Studies. 8. Total Synthesis of (+)-Phyllanthoside: Development of the Mitsunobu Glycosyl Ester Protocol. J. Am. Chem. Soc. 1991, 113, 2092-2112. |
| 181. | A. B. Smith, III, M. Fukui, H. A. Vaccaro and J. R. Empfield. Phyllanthoside-Phyllanthostatin Synthetic Studies. 7. Total Synthesis of (+)-Phyllanthocin and (+)-Phyllanthocindiol. J. Am. Chem. Soc. 1991, 113, 2071-2092. |
| 180. | A. B. Smith, III, J. L. Wood and S. Ōmura. (+)-Mycotrienins I and II: Relative and Absolute Stereochemistry. Tetrahedron Lett. 1991, 32, 841-842. |
| 179. | B.-C. Chen, M. C. Weismiller, F. A. Davis, D. Boschelli, J. R. Empfield and A. B. Smith, III. Enantioselective Synthesis of (+)-Kjellmanianone. Tetrahedron 1991, 47, 173-182. |
 |
1990 |
|---|---|
| 178. | W. K. Lee, P. A. Heiney, M. Ohba, J. N. Haseltine and A. B. Smith, III. Fourier transform infrared study of two truxene-based discotic liquid crystals. Liquid Crystals 1990, 8, 839-850. |
| 177. | A. M. Belcher, G. Epple, K. L. Greenfield, L. E. Richards, I. Kuderling and A. B. Smith, III. Proteins: biologically relevant components of the scent marks of a primate (Saguinus fuscicollis). Chemical Senses 1990, 75, 431-446. |
| 176. | A. B. Smith, III, T. Sunazuka, T. L. Leenay, and J. Kingery-Wood. Total Syntheses of (+) Paspalicine and (+)-Paspalinine. J. Am. Chem. Soc. 1990, 112, 8197-8198. |
| 175. | J. L. Wood, D. R. Jones, R. Hirschmann and A. B. Smith, III. A Versatile, Efficient Synthesis of (–) (2S, 3R, 4S)-2-Amino-1-cyclohexyl-3,4-dihydroxy-6-methylheptane, The Abbott Pseudodipeptidyl Insert. Tetrahedron Lett. 1990, 31, 6329-6330. |
| 174. | A. B. Smith, III, J. L. Wood, W. Wong, A. E. Gould, C. J. Rizzo, S. Funayama and S. Ōmura. (+) Trienomycins A, B, and C: Relative and Absolute Stereochemistry. J. Am. Chem. Soc. 1990, 112,7425-7426. |
| 173. | C. J. Rizzo, J, L. Wood, G. T. Furst, and A. B. Smith, III. Aphidicolin Synthetic Studies, 2. 2D NMR Analysis of Aphidicolin and Its Degradation Products 3α, 18-dihydroxy-17-noraphidicolan-16-one and 3α, 18-Isopropylidenedioxy-17-noraphidicolan-16-one. J. Nat. Prod. 1990, 53, 735-739. |
| 172. | E. Fontes, W. K. Lee, P. A. Heiney, G. Nounesis, C. W. Garland, A. Riera, J. P. McCauley, Jr. and A. B. Smith, III. Smectic-smectic phase transitions in binary liquid-crystalline mixtures of DB5-T8. J. Chem. Phys. 1990, 92, 3917-3929. |
| 171. | A. B. Smith, III, I. Noda, S. W. Remiszewski, N. J. Liverton, and R. Zibuck. Total Synthesis of (+) Latrunculin A. J. Org. Chem. 1990, 55, 3977-3979. |
| 170. | A. B. Smith, III, T. A. Rano, N. Chida, and G. A. Sulikowski. Total Synthesis of (+)-Hitachimycin. J. Org Chem. 1990, 55, 1136-1138. |
| 169. | A. B. Smith, III, J. L. Wood, C. J. Rizzo, G. T. Furst, P. J. Carroll, J. Donohue and S. Ōmura. Solution and Crystal Structures of (+)-Hitachimycin (Stubomycin). J. Org Chem. 1990, 55, 1133-1135. |
| 168. | S. M. Amador, J. M. Pachence, R. Fischetti, J. P. McCauley, Jr., A. B. Smith, III, P. L. Dutton, and J. K. Blasie. X-Ray Diffraction Studies of Protein Monolayers Monolayers Bound to Self-Assembled Monolayers. MRS Proceedings 1990, 177, 393-398. |
| 1989 | |
|---|---|
| 167. | G. Epple, A. M. Belcher, K. L. Greenfield, I. Kuderling, and A. B. Smith, III. Chemical Signals in the Social Environment of a Primate, Saguinus fuscicollis: Fractionation Studies of Complex Scent Mixtures. In K. Doving (ed) Olfaction and Taste X 1989, 10, 36-44. |
| 166. | A. B. Smith, III, J. R. Empfield, and H. A. Vaccaro. Phyllanthoside-Phyllanthostatin Synthetic Studies. 6. An Augmented Spiroketalization Tactic for the Total Synthesis of Phyllanthocin. Tetrahedron Lett. 1989, 30, 7325-7328. |
| 165. | A. B. Smith, III, K. J. Hale, L. M. Laakso, K. Chen, and A. Riéra. FK-506 Synthetic Studies. 3. An Efficient Asymmetric Synthesis of the C(24)-C(34) Fragment of FK-506, FR-900520, and FR 900523. Tetrahedron Lett. 1989, 30, 6963-6966. |
| 164. | A. B. Smith, III, K. J. Hale and J. P. McCauley, Jr. An Efficient New Method for the Desulfonylation of β-Keto Phenylsulfones. Tetrahedron Lett. 1989, 30, 5579-5582. |
| 163. | A. B. Smith, III, G. A. Sulikowski, and K. Fujimoto. Total Synthesis of Natural (–)-Echinosporin. Determination of the Absolute Configuration. J. Am. Chem. Soc. 1989, 111, 8039-8041. |
| 162. | A. B. Smith, III, P. J. Carroll, Y. Kashman and D. Green. Revised Structures of Antheliolides A and B. Tetrahedron Lett. 1989, 30, 3363-3364. |
| 161. | H. A. Vaccaro, R. A. Rivero and A. B. Smith, III. Total Synthesis of (+)-Phyllanthocindiol and (+) Phyllanthostatin 3. Tetrahedron Lett. 1989, 30, 1465-1466. |
| 160. | A. B. Smith, III and K. J. Hale. An Enantioselective Synthesis of the C(10) to C(23) Backbone of the Potent lmmunosuppressant FK506. Tetrahedron Lett. 1989, 30, 1037-1040. |
| 159. | P. J. Carrolll, J. N. Haseltine, R. M. Hochstrasser and A. B. Smith, III. Structures of (E,E)-1,1’-Ethanediylidenebis(2,3-dihydro-1H-indene), (E,E)-1,1’-Ethanediylidenebis(1,2,3,4-tetrahydronaphthalene) and (E,E)-5,5′-Ethanediylidenebis(6,7,8,9-tetrahydro-5H-benzocycloheptene). Acta Crystallogr. 1989, C45, 1803-1805. |
| 158. | A. B. Smith, III and T. L. Leenay. lndole Diterpene Synthetic Studies. 5. Development of a Unified Synthetic Strategy: A Stereocontrolled, Second-Generation Synthesis of (–)-Paspaline. J. Am. Chem. Soc. 1989, 111, 5761-5768. |
| 157. | R. E. Mewshaw, M. D. Taylor, and A. B. Smith, III. lndole Diterpene Synthetic Studies. 2. First Generation Total Synthesis of (–)-Paspaline. J. Org. Chem. 1989, 54, 3449-3462. |
| 156. | A. B. Smith, III, A. T. Lupo, Jr., M. Ohba, and K. Chen. Total Synthesis of (+)-Hydroxyjatrophone A and (+)-Hydroxyjatrophone B. J. Am. Chem. Soc. 1989, 111, 6648-6656. |
| 155. | M. Lee, J. N. Haseltine, A. B. Smith, III, and R. M. Hochstrasser. lsomerization Processes of Electronically Excited Stilbene and Diphenylbutadiene in Liquids: Are They One-Dimensional? J. Am. Chem. Soc. 1989, 111, 5044-5051. |
| 154. | J. L. Wood, N.J. Liverton, M. Visnick, and A. B. Smith, III. An Efficient Photochemical Approach to the trans-Bicyclo[5.1.0]octene Ring System. J. Am. Chem. Soc. 1989, 111, 4530-4532. |
| 153. | P. A. Heiney, E. Fontes, W. H. de Jeu, A. Riera, P. Carroll and A. B. Smith, III. Frustration and helicity in the ordered phases of a discotic compound. J. Physique (France) 1989, 50, 461-483. |
| 152. | A. B. Smith, III. Hitachimycin (a.k.a. stubomycin): structural and synthetic studies. Pure Appl. Chem. 1989, 61, 405-408. |
| 151. | W. K. Lee, B. A. Wintner, E. Fontes, P. A. Heiney, M. Ohba, J. N. Haseltine and A. B. Smith, III. Reentrant isotropic phase in a discotic liquid crystal mixture. Liquid Crystals 1989, 4, 87-102. |
| 150. | K. M. Nordstrom, A. M. Belcher, G. Epple, K. L. Greenfield, J. J. Leyden, and A. B. Smith, III. Skin Surface Microflora of the Saddle-Back Tamarin Monkey (Saguinus fuscicollis). J. Chem. Ecol. 1989, 15, 629-639. |
| 149. | A. B. Smith, III, J. N. Haseltine, and M. Visnick. Tremorgenic lndole Alkaloid Studies. 6. Preparation of an Advanced Intermediate for the Synthesis of Penitrem D. Synthesis of an Indole-Oxocane. Tetrahedron 1989, 45, 2431-2449. |
| 148. | A. B. Smith, III and B. D. Dorsey. Evolution of a Synthetic Strategy, Part 11: Total Synthesis of (–) Casbene and (–)-Bertyadional. In Strategies and Tactics in Organic Synthesis. Lindberg, Ed. Academic Press: New York, NY, 1989; pp 369-414. |
| 1988 | |
|---|---|
| 147. | G. Epple, A. Belcher, K. L. Greenfield, I. Kuderling, K. Nordstrom and A. B. Smith, III. Scent mixtures used as social signals in two primate species: Saguinus fuscicollis and Saguinus o. oedipus. In Perception of Complex Smells and Tastes. D. Laing (Ed.). Academic Press: Sydney, 1988; pp 1-25. |
| 146. | J. Haseltine, M. Visnick and A. B. Smith, III. A Concise Route to the Penitrem Series of Tremorgenic Mycotoxins: Preparation of an Oxocane-Fused lndole. J. Org. Chem. 1988, 53, 6160-6162. |
| 145. | V. L. Windisch, A. B. Smith, III, and R. M. Hochstrasser. Unimolecular Photodissociation of s-Tetrazine and Derivatives. J. Phys. Chem. 1988, 92, 5366-5370. |
| 144. | C. J. Rizzo and A. B. Smith, III. A New End Game for Aphidicolin. Tetrahedron Lett. 1988, 29, 2793-2796. |
| 143. | A. B. Smith, III and T. L. Leenay. Indole-Diterpene Synthetic Studies. 4. A Stereocontrolled, Second Generation Synthesis of (–)-Paspaline. Tetrahedron Lett. 1988, 29, 2791-2792. |
| 142. | A. B. Smith, III and T. L. Leenay. Indole-Diterpene Synthetic Studies. 3. A Unified Synthetic Strategy for the Simple lndole Tremorgens. Tetrahedron Lett. 1988, 29, 2787-2790. |
| 141. | A. B. Smith, III, B. D. Dorsey, M. Ohba, A. T. Lupo, Jr., and M. S. Malamas. Preparation, Reactivity, and Spectral Properties of 1,3-Dioxin Vinylogous Esters: Versatile β-Ketovinyl Cation Equivalents. J. Org. Chem. 1988, 53, 4314-4325. |
| 140. | A. Belcher, G. Epple, I. Kuderling, and A. B. Smith, III. Volatile Components of Scent Material from Cotton-Top Tamarin (Saguinus o. oedipus): A Chemical and Behavioral Study. J. Chem. Ecol. 1988, 14, 1367-1384. |
| 139. | A. B. Smith, III and P. K. Trumper. Theoretical Evaluation of Stereoelectronic Diastereofacial Selectivity in the Conjugate Addition of Cuprates to 5-Substituted Cyclopentenones. Tetrahedron Lett. 1988, 29, 443-446. |
| 138. | A. B, Smith, III, N. K. Dunlap and G. A. Sulikowski. Cuprate Additions to 5-Methoxycyclopentenones: A Novel Stereoelectronic Effect. Tetrahedron Lett. 1988, 29, 439-442. |
| 137. | A. B. Smith, III, T. L. Leenay, H.-J. Liu, L. A. K. Nelson, and R. G. Ball. A Caveat on the Swern Oxidation. Tetrahedron Lett. 1988, 29, 49-52. |
| 136. | E. Fontes, P. A. Heiney, M. Ohba, J. N. Haseltine, and A. B. Smith, III. Molecular disorder in columnar-phase discotic liquid-crystal strands. Phys. Rev. A 1988, 37, 1329-1334. |
| 1987 | |
|---|---|
| 135. | G. Epple, M. C. Alveario, A. M. Belcher, and A. B. Smith, III. Species and Subspecies Specificity in Urine and Scent Marks of Saddle-back Tamarins (Saguinus Fuscicollis). Intern. J. Primatol. 1987, 8, 663. |
| 134. | A. B. Smith, III, K. J. Hale and H. A. Vaccaro. The Total Synthesis of (+)-Phyllanthostatin 2. Tetrahedron Lett. 1987, 28, 5591-5594, |
| 133. | C. J. Rizzo, N. K. Dunlap, and A. B. Smith, III. A Convenient Preparation of 4- and 5-Substituted Cyclopentenones: A Short Synthesis of Methylenomycin B. J. Org. Chem. 1987, 52, 5280-5283. |
| 132. | A. B. Smith, III, Y. Yokoyama, N. K. Dunlap, A. Hadener, and C. Tamm. Total Synthesis of Dechloromikrolin: A Structural Reassignment with Biosynthetic Implications. Tetrahedron Lett. 1987, 28, 3663-3666. |
| 131. | A. B. Smith, III, Y. Yokoyama, D. M. Huryn, and N. K. Dunlap. Total Synthesis of (+)-Mikrolin. Tetrahedron Lett. 1987, 28, 3659-3662. |
| 130. | A. B. Smith, III, K. J. Hale, and H. A. Vaccaro. The Total Synthesis of (–)-Phyllanthostatin-1. J. Chem. Soc., Chem. Commun. 1987, 1026-1028. |
| 129. | R. A. Gleeson, M. A. Adams, and A. B. Smith, III. Hormonal Modulation of Pheromone-Mediated Behavior in a Crustacean. Biol. Bull. 1987, 172, 1-9. |
| 128. | A. B. Smith, III and R. A. Rivero. Total Synthesis of (+)-Phyllanthoside. J. Am. Chem. Soc. 1987, 109, 1272-1274. |
| 127. | A. B. Smith, III and M. Fukui. Total Synthesis of (+)-Phyllanthocin. J. Am. Chem. Soc. 1987, 109, 1269-1272. |
| 1986 | |
|---|---|
| 126. | A. B. Smith, III, K. J. Hale, and R. A. Rivero. An Efficient Synthesis of Glycosyl Esters Exploiting the Mitsunobu Reaction. Tetrahedron Lett. 1986, 27, 5813-5816. |
| 125. | M. Lee, A. J. Bain, P. J. McCarthy, C. H. Hans, J. N. Haseltine, A. B. Smith, III, and R. M. Hochstrasser. Picosecond photoisomerization and rotational reorientation dynamics in solution. J. Chem. Phys. 1986, 85, 4341-4347. |
| 124. | A. B. Smith, III, R. Zibuck and N. J. Liverton. Total Synthesis of the Latrunculins: Architecturally Novel Marine Natural Products. In New Synthetic Methodology and Functionally Interesting Compounds. Z. Yoshida (Ed.). Elsevier: New York, 1986; pp 183-202. |
| 123. | E. Fontes, P. A. Heiney, J. L. Haseltine, and A. B. Smith, III. High resolution X-ray scattering study of the multiply reentrant polar mesogen DB90N02. J. Physique 1986, 47, 1533-1539. |
| 122. | A. B. Smith, III, B. D. Dorsey, M. Visnick, T. Maeda, and M. S. Malamas. Synthesis of (–) Bertyadionol. J. Am. Chem. Soc. 1986, 108, 3110-3112. |
| 121. | P. J. Carroll, N. J. Liverton and A. B. Smith, III. Structure of 1,1a,4,5,6,8,9,9a-Octahydro-3-methoxy-1,1,2-trimethyl-(1aS-trans)-7H-cyclopropa[3,4]cyclohept[1,2-e]inden-7-one. Acta Cryst., C 1986, 42, 1594-1596. |
| 120. | A. B. Smith, III, N. J. Liverton, N. J. Hrib, H. Sivaramakrishnan, and K. Winzenberg. Total Synthesis of (+) Jatropholones A and B: Exploitation of the High-pressure Technique. J. Am. Chem. Soc. 1986, 108, 3040-3048. |
| 119. | A. B. Smith, III, M. Visnick, J. N. Haseltine and P. A. Sprengeler. Organometallic Reagents in Synthesis: A New Protocol for Construction of the Indole Nucleus. Tetrahedron 1986, Symposium in Print, 42, 2957-2969. |
| 118. | Schow, Steven R.; Bloom, Jonathan D.; Thompson, Andrew S.; Winzenberg, Kevin N.; Smith, Amos B., III. Milbemycin-avermectin studies. 5. Total synthesis of milbemycin b3 and its C(12) epimer. Journal of the American Chemical Society (1986), 108 (10), 2662-74. |
| 117. | R. Zibuck, N. J. Liverton, and A. B. Smith, III. Total Synthesis of (+)-Latrunculin B. J. Am. Chem. Soc. 1986, 108, 2451-2453. |
| 116. | G. Epple, A. M. Belcher and A. B. Smith, III. Chemical Signals in Callithrichid Monkeys – A Comparative Review. In Chemical Signals in Vertebrates IV. D. Duval (Ed.). Plenum, 1986. |
| 115. | A. M. Belcher, A. B. Smith, III, P. C. Jurs, B. Lavine, and G. Epple. Analysis of Chemical Signals in a Primate Species (Saquinus fuscicollis): Use of Behavioral, Chemical, and Pattern Recognition Methods. J. Chem. Ecology 1986, 12, 513-531. |
| 114. | A. B. Smith, III, P. A. Levenberg, and J. Z. Suits. Chromium (II) Reagents; 1. Reduction of α-Acetylenic Ketones to trans-Enones. Synthesis 1986, 184-189. |
| 1985 | |
|---|---|
| 113. | A. B. Smith, III and S. N. Kilényi. Avermectin-Milbemycin Studies. 4. An Expedient Two-step Preparation of p Hydroxybenzoates. Tetrahedron Lett. 1985, 26, 4419-4422. |
| 112. | A. B. Smith, III and A. S. Thompson. Avermectin-Milbemycin Studies. 3. Synthesis of a Milbemycin-Avermectin Hybrid. Tetrahedron Lett. 1985, 26, 4283-4286. |
| 111. | A. B. Smith, III and A. S. Thompson. Avermectin-Milbemycin Studies. 2. An Efficient Chemical Degradation of Avermectin B1a. Tetrahedron Lett. 1985, 26, 4279-4282. |
| 110. | A. B. Smith, III, N. J. Liverton, N. J. Hrib, H. Sivaramakrishnan, and K. Winzenberg. Total Synthesis of Jatropholone A and B. J. Org. Chem. 1985, 50, 3239-3241. |
| 109. | A. B. Smith, III and M. Visnick. An Expedient Synthesis of Substituted Indoles. Tetrahedron Lett. 1985, 26, 3757-3760. |
| 108. | A. B. Smith, III and R. Mewshaw. Total Synthesis of (–)-Paspaline. J. Am. Chem. Soc. 1985, 107, 1769-1771. |
| 107. | A. B. Smith, III, and D. M. Huryn. Total Synthesis of (–)-Gilmicolin. J. Org. Chem. 1985, 50, 1342-1344. |
| 106. | A. B. Smith, III, B. A. Wexler, C.-Y. Tu, and J. P. Konopelski. Stereoeletroncic Effects in the Cationic Rearrangements of [4.3.2] Propellanes. J. Am. Chem. Soc. 1985, 107, 1308-1320 |
| 105. | Smith, Amos B., III; Belcher, Anne M.; Epple, Gisela; Jurs, Peter C.; Lavine, Barry. Computerized pattern recognition: a new technique for the analysis of chemical communication. Science (Washington, DC, United States) (1985), 228 (4696), 175-7. |
| 104. | V. A. Santopietro, J. Donohue, and A. B. Smith, III. Crystal and molecular structure of hydroxyjatrophone C. J. Cryst. Spect. Res. 1985, 15, 247-255. |
| 103. | G. Epple and A. B. Smith, III. The Primates II: A Case Study of Saddle-Back Tamarin, Saguinus Fuscicollis. In Social Odours in Mammals. R. E. Brown and D. W. MacDonald (Eds.). Oxford University Press, Oxford, 1985. |
| 1984 | |
|---|---|
| 102. | A. B. Smith, III and J. P. Konopelski. Total Synthesis of (+)-Quadrone: Assignment of Absolute Stereochemistry. J. Org. Chem. 1984. 49, 4094-4095. |
| 101. | A. B. Smith, III and R. Mewshaw. An Efficient Approach to Chiral, Nonracemic trans-Decahydro-5,8-adimethyl-1,6-naphthalenedione Derivatives: Total Synthesis of (+) Pallescensin A. J. Org. Chem. 1984, 49, 3685-3689. |
| 100. | A. B. Smith, III and B. A. Wexler. Acid-Catalyzed Rearrangements of Tricyclo[4.3.2]propellane Derivatives. Tetrahedron Lett. 1984, 25, 2317-2320. |
| 099. | A. B. Smith, III and A. S. Thompson. An Enantioselective Total Synthesis of (–)-Talaromycins A and B. J. Org. Chem. 1984, 49, 1469-1471. |
| 098. | E. R. Koft and A. B. Smith, III. Intramolecular [2+2] Photochemical Cycloadditions. 3. Perhydrohistrionicotoxin Synthetic Studies: Synthesis of Spiro[4.5]decanones via Intramolecular [2+2] Photocycloaddition. J. Org. Chem. 1984, 49, 832-836. |
| 097. | E. R. Koft and A. B. Smith, III. Intramolecular [2+2] Photocyclizations. 2. Total Synthesis of (±)-Hibiscone C (Gmelofuran). J. Am. Chem. Soc. 1984, 106, 2115-2121. |
| 096. | A. B. Smith, III, B. H. Toder, R. E. Richmond, and S. J. Branca. Vinyloygous Wolff Rearrangement. 5. Mechanistic Studies. J. Am. Chem. Soc. 1984, 106, 4001-4009. |
| 095. | A. B. Smith, III, B. H. Toder, and S. J. Branca. Vinylogous Wolff Rearrangement. 4. General Reaction of β,γ-Unsaturated α’-Diazo Ketones. J. Am. Chem. Soc. 1984, 106, 3995-4001. |
| 094. | A. B. Smith, III. Evolution of a Synthetic Strategy: Total Synthesis of Jatrophone. In Strategies and Tactics In Organic Synthesis. T. Lindberg (Ed.). New York: Academic Press, 1984; pp 223-274. |
| 093. | J. Donohue, A. B. Smith, III, and P. J. Carroll. Crystal and molecular structure of reductiomycin. J. Cryst. Spect. Res. 1984, 14, 35-43. |
| 092. | R. A. Gleeson, M. A. Adams, and A. B. Smith, III. Characterization of a Sex Pheromone in the Blue Crab, Callinectes Sapidus: Crustecdysone Studies. J. Chem. Ecology 1984, 10, 913-921. |
| 1983 | |
|---|---|
| 091. | M. D. Taylor, A. B. Smith, III, and M. S. Malamas. Jatrophone, Jatrophone Derivatives, and Analogues. Conformation and Reactions with Propanethiol. J. Org. Chem. 1983, 48, 4257-4261. |
| 090. | M. D. Taylor and A. B. Smith, III. Total Synthesis of (+)-Hanegokedial. Tetrahedron Lett. 1983, 24, 1867-1870 |
| 089. | A. B. Smith, III and R. E. Richmond. Total Synthesis of the Paniculides. J. Am. Chem. Soc. 1983, 105, 575-585. |
| 088. | A. B. Smith, III and D. Boschelli. Stereocontrolled Total Synthesis of (±) Xanthocidin, Two Diastereomers, (±) Epixanthocidin and (±) β lsoxanthocidin and (±) Desdihydroxy-4,5-didehydroxanthocidin, A Likely Biosynthetic Precursor. J. Org. Chem. 1983, 48, 1217-1226. |
| 087. | A. B. Smith, III and S. R. Schow. Spiroketals Useful as Intermediates in the Synthesis of Milbemycin and Avermectin Macrolides, US Patent 4,408,059; Canadian Patent 1 196630. |
| 086. | A. B. Smith, III, S. J. Branca, M. A. Guaciaro, P. M. Wovkulich, and A. Korn. 2-Hydroxymethyl-2-Cyclopentenone. Organic Syntheses 1983, 61, 65-70; Organic Syntheses Collective, Vol. VII, 1983; pp 271 -275. |
| 085. | M. D. Taylor, A. B. Smith, III, G. T. Furst, S. P. Gunasekara, C. A. Bevelle, G. A. Cordell, N. R. Farnsworth, S. M. Kupchan, H. Uchida, A. R. Branfman, R. G. Dailey, Jr., and A. T. Sneden. New Antileukemic Jatrophone Derivatives from Jatropha gossypiifolia: Structural and Stereochemical Assignment through Nuclear Magnetic Resonance Spectroscopy. J. Am. Chem. Soc. 1983, 105, 3177-3183. |
| 1982 | |
|---|---|
| 084. | A. B. Smith, III, S. R. Schow, J. D. Bloom, A. S. Thompson, and K. N. Winzenberg. Total Synthesis of Milbemycin β3. J. Am. Chem. Soc. 1982, 104, 4015-4018. |
| 083. | E. R. Koft and A. B. Smith, III. Total Synthesis of Hibiscone C (Gmelofuran). J. Am. Chem. Soc. 1982, 104, 5568-5570. |
| 082. | M. D. Taylor, G. Minaskanian, K. N. Winzenberg, P. Santone, and A. B. Smith, III. Preparation, Stereochemistry, and Nuclear Magnetic Resonance Spectroscopy of 4-Hydroxy-(acetoxy)bicyclo[5.1.0]octanes. Synthesis of (–)- and (±)-8,8-Dimethylbicyclo[5.1.0]oct-2-en-4-one. J. Org. Chem. 1982, 47, 3960-3964. |
| 081. | E. R. Koft and A. B. Smith, III. Total Synthesis of (±)-Mycorrhizin A and (±)-Dechloromycorrhizin A. J. Am. Chem. Soc. 1982, 104, 2659-2661. |
| 080. | A. B. Smith, III and M. S. Malamas. Jatrophone Analogues: Synthesis of cis- and trans-Normethyljatropholactones. J. Org. Chem. 1982, 47, 3442-3447. |
| 079. | A. B. Smith, III and P. J. Jerris. Total Synthesis of (±)-Modhephen and Its Epimer, (±)-Epimodhephene. J. Org. Chem. 1982, 47, 1845-1855. |
| 078. | A. Mehreteab, J. R. Andrews, A. B. Smith, III, and R. M. Hochstrasser. Two-Photon Excitation and Fluorescence Lifetimes of Silver Atoms in Rare Gas Matrices. J. Phys. Chem. 1982, 86, 888-891. |
| 077. | B. A. Wexler, B. H. Toder, G. Minaskanian, and A. B. Smith, III. Efficient Regiocontrolled Synthesis of Sarkomycin and Homosarkomycin. J. Org. Chem. 1982, 47, 3333-3335. |
| 076. | A. B. Smith, III, S. J. Branca, N. N. Pilla, and M. A. Guaciaro. Stereowntrolled Total Synthesis of (±) Pentenomycins I-III, Their Epimers, and Dehydropentenomycin I. J. Org. Chem. 1982, 47, 1855-1869. |
| 075. | A. B. Smith, III, B. A. Wexler, and J. Slade. Synthesis of (±)-Descarboxylquadrone. Tetrahedron Lett. 1982, 23,1631-1634. |
| 074. | A. B. Smith, III, B. H. Toder, P. Carroll and, J. Donohue. Andrographolide: an X-ray crystallographic analysis. J. Cryst. Spect. Res. 1982, 12, 309-319. |
| 1981 | |
|---|---|
| 073. | G. Epple, N. F. Golob, M.-S. Cebul and A. B. Smith, III. Communication by scent in some Callitrichidae (Primates) – An interdisciplinary approach. Chem. Senses 1981, 6, 377-390. |
| 072. | A. B. Smith, III and R. K. Dieter. The Acid Promoted Decomposition of α-Diazo Ketones, Tetrahedron Report #111. Tetrahedron 1981, 37, 2407-2439. |
| 071. | D. Boschelli, A. B. Smith, III, O. D. Stringer, R. H. Jenkins, Jr., and F. A. Davis. An Asymmetric Synthesis of (+) Kjellmanianone. Tetrahedron Lett. 1981, 22, 4385-4388. |
| 070. | A. B. Smith, III and R. E. Richmond. A Common Strategy for Construction of the Paniculides (A-C): Total Synthesis of Paniculide A. J. Org. Chem. 1981, 46, 4814-4816. |
| 069. | D. Boschelli and A. B. Smith, III. Total Synthesis of (±)-Xanthocidin and (±)-Desdihydroxy-4,5-dihydroxanthocidin. Tetrahedron Lett. 1981, 22, 3733-3736. |
| 068. | J. L. Wellington, G. K. Beauchamp and A. B. Smith, III. Stability of Chemical Communicants of Gender in Guinea Pig Urine. Behavioral and Neural Bio. 1981, 32, 364-375. |
| 067. | A. B. Smith, III and P. A. Levenberg. Oxidation of p-Hydroxyketones and Esters: A Convenient Synthesis of 1,3-Diketones and β-Ketoesters. Synthesis 1981, 567-570. |
| 066. | A. B. Smith, III and R. K. Dieter. Lewis Acid Promoted Decomposition of Unsaturated α-Diazo Ketones. 3. Stereochemical Consequences of Polyolefinic Cyclizations Initiated by the α-Diazo Ketone. J. Am. Chem. Soc. 1981, 103, 2017-2022. |
| 065. | A. B. Smith, III and R. K. Dieter. Lewis Acid Promoted Decomposition of Unsaturated α-Diazo Ketones. 2. A New Initiator for Polyolefinic Cationic Cyclization. J. Am. Chem. Soc. 1981, 103, 2009-2016. |
| 064. | A. B. Smith, III, B. H. Toder, S. J. Branca, and R. K. Dieter. Lewis Acid Promoted Decomposition of Unsaturated α-Diazo Ketones. 1. An Efficient Approach to Simple and Annulated Cyclopentenones. J. Am. Chem. Soc. 1981, 103, 1996-2008 |
| 063. | A. B. Smith, III, P. A. Levenberg, P. J. Jerris, R. M. Scarborough, Jr., and P. M. Wovkulich. Synthesis and Reactions of Simple 3(2H)-Furanones. J. Am. Chem. Soc. 1981, 103, 1501-1513. |
| 062. | P. J. Jerris and A. B. Smith, III. Synthesis and Configurational Assignment of Geiparvarin: A Novel Antitumor Agent. J. Org. Chem. 1981, 46, 577-585. |
| 061. | A. B. Smith, III, M. A. Guaciaro, S. R. Schow, P. M. Wovkulich, B. H. Toder, and T. W. Hall. A Strategy for the Total Synthesis of Jatrophone: Synthesis of Normethyljatrophone. J. Am. Chem. Soc. 1981, 103, 219-222. Also see: 103,4652. |
| 060. | A. B. Smith, III, and P. J. Jerris. Total Synthesis of (±)-Modhephene. J. Am. Chem. Soc. 1981, 103, 194-195. |
| 059. | D. Boschelli, R. M. Scarborough, Jr. and A. B. Smith, III. Total Synthesis of (±)-Desepoxy-4,5- didehydromethylenomycin A. Tetrahedron Lett. 1981, 22, 19-22. |
| 1980 | |
|---|---|
| 058. | G. K. Beauchamp, J. W. Lerman, C. J. Wysocki, J. G. Brand, J. L. Kubie and A. B. Smith, III. Chemical Communication in the Guinea Pig: Urinary Components of Low Volatility and Their Access to the Vomeronasal Organ. In Chemical Signals: Vertebrates and Aquatic Invertebrates. Plenum Press: New York, 1980; p 327. |
| 057. | M. Paczkowski, R. Pierce, A. B. Smith, III, and R. M. Hochstrasser. Consecutive Processes in the Photolysis of Dimethyl-s-Tetrazine Molecules in the Vapor Phase. Chem. Phys. Lett. 1980, 72, 5-9. |
| 056. | A. B. Smith, III and N. N. Pilla. A Stereospecific Total Synthesis of (±)-Epipentenomycin I, (±)-Epipentenomycin II, and (±)-Epipentenomycin III. Tetrahedron Lett. 1980, 21, 4691-4694. |
| 055. | A. B. Smith, III, B. A. Wexler and J. S. Slade. Bis-β, β’-Conjugate Addition. Tetrahedron Lett. 1980, 21, 3237-3240. |
| 054. | A. B. Smith, III and P. J. Jerris. Synthesis of Geiparvarin: A Novel Antitumor Agent Possessing a 3(2H) Furanone Ring. Tetrahedron Lett. 1980, 21, 711-714. |
| 053. | A. B. Smith, III and R. M. Scarborough, Jr. Ruthenium Tetroxide Oxidation of Simple Ethers: A Systematic Study. Synth. Commun. 1980, 10, 205-211. |
| 052. | G. Epple, M. C. Alveario, N. F. Golob, and A. B. Smith, III. Stability and Attractiveness Related to Age of Scent Marks of Saddle Back Tamarins (Saguinus fuscicollis). J. Chem. Ecology 1980, 6, 735-748. |
| 051. | R. M. Scarborough, Jr., B. H. Toder, and A. B. Smith, III. A Stereospecific Total Synthesis of (±) Methylenomycin A and Its Epimer, (±)-Epimethylenomycin A. J. Am. Chem. Soc. 1980, 102, 3904-3913. |
| 1979 | |
|---|---|
| 050. | G. Epple, N. F. Golob and A. B. Smith, III. Odor Communication in the Tamarin Saguinus fuscicollis (Callitrichidae): Behavioral and Chemical Studies. In Chemical Ecology: Odour Communication in Animals. F. J. Ritter (Ed.). Elsevier/North-Holland, 1979; pp 117-130. |
| 049. | B. H. Toder, D. Boschelli, and A. B. Smith, III. Crystal and molecular structure of geiparvarin. J. Crystal and Molecular Structure, 1979, 9, 189-198. |
| 048. | P. J. Jerris, P. M. Wovkulich, and A. B. Smith, III. A Facile Synthesis of Simple Tetronic Acids and Pulvinones. Tetrahedron Lett. 1979, 4517-4520. |
| 047. | J. L. Wellington, K. J. Byrne, G. Preti, G. K. Beauchamp, and A. B. Smith, III. Perineal Scent Gland of Wild and Domestic Guinea Pigs: A Comparative Chemical and Behavioral Study. J. Chem. Ecology 1979, 5, 737-751. |
| 046. | N. F. Golob, R. G. Yarger, and A. B. Smith, III. Primate Chemical Communication, Part III: Synthesis of the Major Volatile Constituents of the Marmoset (Saguinus fuscicollis) Scent Mark. J. Chem. Ecology 1979, 5, 543-555. |
| 045. | R. M. Scarborough, Jr., A. B. Smith, III, W. E. Barnette, and K. C. Nicolaou. Organoselenium-Induced Ring Closures: Cyclization of Dienes with ‘PhSeOH’ to Form Cyclic Ethers. J. Org. Chem. 1979, 44, 1742-1744. |
| 1978 | |
|---|---|
| 044. | A. B. Smith, III and R. M. Scarborough, Jr. γ-Alkylation of Lithium Dienolates Derived from 3(2H) Furanones and Related α,β-Unsaturated Carbonyl Compounds. Tetrahedron Lett. 1978, 4193-4196. |
| 043. | M. A. Guaciaro, P. M. Wovkulich, and A. B. Smith, III. An Efficient Synthesis of α-Substituted α,β Unsaturated Ketones Employing a Versatile Latent α-Ketovinyl Anion Equivalent. Tetrahedron Lett. 1978, 4661-4664. |
| 042. | S. J. Branca and A. B. Smith, III. A Stereospecific Total Synthesis of (±)-Pentenomycin I, (±) Pentenomyci II, and Dehydropentenomycin I Exploiting a Versatile Latent α-Ketovinyl Anion Equivalent. J. Am. Chem. Soc. 1978, 100, 7767-7768. |
| 041. | B. Dellinger, M. A. Paczkowski, R. M. Hochstrasser, and A. B. Smith, III. Observation of Transient Intermediates in the Photochemical Decomposition of Substituted s-Tetrazines. J. Am. Chem. Soc. 1978, 100, 3242-3243. |
| 040. | A. B. Smith, III and P. J. Jerris. Conjugated Addition to 2,2-Dimethyl-3(2H)-furanone: Support for the Baldwin Rules for Ring Closure. Syn. Commun. 1978, 8, 421-426. |
| 039. | A. B. Smith, III and R. M. Scarborough, Jr. Nucleophilic Ring Cleavage of Mono-activated Cyclopropanes via Sodium and Lithium Phenyl Selenolate. Tetrahedron Lett. 1978, 1649-1652. |
| 038. | B. H. Toder and A. B. Smith, III. Crystal and molecular structure of (±)-Cyclomethylenomyci A. J. Crystal and Molecular Structure 1978, 8, 1-8. |
| 1977 | |
|---|---|
| 037. | G. Preti, A. B. Smith, III, and G. K. Beauchamp. Chemical and Behavioral Complexity in Mammalian Chemical Communication Systems: Guinea Pigs (Cavia porcellus), Marmosets (Saguinus fuscicollis) and Humans (Homo sapiens). In Chemical Signals in Vertebrates. D. Muller-Schwarze and M. M. Mozell (Eds.). Plenum Press: New York, 1977; pp 95-114. |
| 036. | R. M. Scarborough, Jr. and A. B. Smith, III. An Efficient General Synthesis of ω-Olefinic Methyl Esters. Tetrahedron Lett. 1977, 8, 4361-4364. |
| 035. | R. M. Scarborough, Jr., and A. B. Smith, III. A Stereospecific Total Synthesis of (±)-Methylenomycin A. A Novel Antibiotic Possessing an α-Methylene Ketone Functionality. J. Am. Chem. Soc. 1977, 99, 7085-7087. |
| 034. | B. Dellinger, R. M. Hochstrasser, and A. B. Smith, III. Measurements of the Relative Chemical Reactivity of Triplet Spin Substates. J. Am. Chem. Soc. 1977, 99, 5834-5835. |
| 033. | R. L. Lichter, P. R. Srinivasan, A. B. Smith, III, R. K. Dieter, C. T. Denny, and J. M. Schulman. 13C and 15N Nuclear Magnetic Resonance Parameters of Ethyl Diazoacetate. J. Chem. Soc., Chem. Comm. 1977, 366-368. |
| 032. | B. Dellinger, D. S. King, R. M. Hochstrasser, and A. B. Smith, III. High-Resolution Optical Spectroscopy and Laser Isotope Enrichment of Matrix-Isolated s-Tetrazine in Argon. J. Am Chem. Soc. 1977, 99, 7138-7142. |
| 031. | B. Dellinger, D. S. King, R. M. Hochstrasser, and A. B. Smith, III. Laser Induced Isotope Enrichment in a Rare Gas Matrix. J. Am. Chem. Soc. 1977, 99, 3197-3198. |
| 030. | R. M. Hochstrasser, D. S. King, and A. B. Smith, III. Spectroscopy, Photophysics, and Photochemistry of Dimethyl-s-tetrazine and Phenyl-s-tetrazine in Crystals and Mixed Crytsals at Low Temperatures. J. Am. Chem. Soc. 1977, 99, 3923-3933. |
| 029. | S. J. Branca, R. L. Lock, and A. B. Smith, III. Exploitation of the Vinylogous Wolff Rearrangement. An Efficient Total Synthesis of (±)-Mayurone, (±)-Thujopsene, and (±)-Thujopsadience. J. Org. Chem. 1977, 42, 3165-3168. |
| 028. | S. J. Branca and A. B. Smith, III. Preparation, Stereochemistry, and Nuclear Magnetic Resonance Spectroscopy of Methyl 1,3-Dimethyl-2-oxocyclohexaneacetates and Related Derivatives. J. Org. Chem. 1977, 42, 1026-2030. |
| 027. | B. H. Toder, S. J. Branca, and A. B. Smith, III. Photochemistry of 2(5H)-Furanone. Hydrogen Abstraction by the β-Carbon Atom. J. Org. Chem. 1977, 42, 904-906. |
| 026. | D. S. King, C. T. Denny, R. M. Hochstrasser, and A. B. Smith, III. The Photochemical Decomposition of 1,4-s-Tetrazine-15N2. J. Am. Chem. Soc. 1977, 99, 271-273. |
| 025. | A. B. Smith, III, K. J. Byrne, and G. K. Beauchamp. Syn- and Anti-Phenylacetaldehyde Oxime: Two Novel Testosterone-Dependent Mammalian Metabolites. J. Chem. Ecology 1977, 3, 309-319. |
| 024. | A. B. Smith, III and R. K. Dieter. β,γ-Unsaturated Diazo Ketones. A New Initiator for Polyolefinic Cationic Cyclization. J. Org. Chem. 1977, 42, 396-397. |
| 023. | R. G. Yarger, A. B. Smith, III, G. Preti, and G. Epple. The Major Volatile Constituents of the Scent Mark of a South American Primate (Saguinus fuscicollis, Callithricidae). J. Chem. Ecology 1977, 3, 45-46. |
| 1976 | |
|---|---|
| 022. | A. B. Smith, III, B. H. Toder, and S. J. Branca. Stereochemical Consequences of the Vinylogous Wolff Rearrangement. J. Am. Chem. Soc. 1976, 98, 7456-7458. |
| 021. | A. B. Smith, III, R. G. Yarger, and G. M. Epple. The Major Volativel Constituents of the Marmoset (Saguinus fuscicollis) Scent Mark. Tetrahedron Lett. 1976, 983-986 |
| 020. | A. B. Smith, III and R. K. Dieter. Intramolecular Photochemical Oxetane Formation in Two β,γ-γ’,δ’-Diunsaturated Ketones. Tetrahedron Lett. 1976, 327-330. |
| 1975 | |
|---|---|
| 019. | A. B. Smith, III, S. J. Branca, and B. H. Toder. A New Approach to Simple Simple Cyclopentenones: Application to the Synthesis of Dihydro and cis-Jasmone. Tetrahedron Lett. 1975, 4225-4228. |
| 018. | B. H. Toder, S. J. Branca, R. K. Dieter and A. B. Smith, III. Regiospecific Methylation of Cyclopentenone Derivatives. Synth. Commun. 1975, 5, 435-439. |
| 017. | A. B. Smith, III. Acid-catalysed Decomposition of By-Unsaturated Diazomethyl Ketones: A New Cyclopentenone Annotation. J. Chem. Soc., Chem. Commun. 1975, 274-275. |
| 016. | A. B. Smith, III, L. Brodsky, S. Wolff, and W. C. Agosta. The Photochemistry of Two Rigid p,y-Cyclopropyl Ketones, exo- and endo-Tricyclo[3,2,1,02,4]octan-6-one. J. Chem. Soc., Chem. Commun. 1975, 509-510. |
| 1974 | |
|---|---|
| 015. | A. B. Smith, III. A Vinylogous Wolff Rearrangement; Copper Sulphate-catalysed Decomposition of Unsaturated Diazomethyl Ketones. J. Chem. Soc., Chem. Commun. 1974, 695-696. |
| 014. | A. B. Smith, III, and W. C. Agosta. Photochemical Reactions of 3-Substituted Cyclopentenyl Ketones. J. Am. Chem. Soc. 1974, 96, 3289-3295. |
| 013. | S. Wolff, A. B. Smith, III, and W. C. Agosta. Preparation of Some Bicyclic Ethers. J. Org. Chem. 1974, 39, 1607-1612. |
| 1973 | |
|---|---|
| 012. | A. B. Smith, III, and W. C. Agosta. Photochemical Reactions of 1-Cyclopentenyl and 1-Cyclohexenyl Ketones. J. Am. Chem. Soc. 1973, 95, 1961-1968. |
| 1972 | |
|---|---|
| 011. | Wolff, Steven; Schreiber, William L.; Smith, Amos B., III; Agosta, William C. Photochemistry of cyclopentenones. Hydrogen abstraction by the b-carbon atom. Journal of the American Chemical Society (1972), 94 (22), 7797-806. |
| 010. | Smith, Amos B., III; Foster, A. M.; Agosta, William C. Two novel routes to spiro[3.4]octan-1-ones. Journal of the American Chemical Society (1972), 94 (14), 5100-1. |
| 009. | Smith, Amos B., III; Agosta, William C. Photochemistry of 6-propyl-2-cyclohexenone. Journal of Organic Chemistry (1972), 37 (8), 1259-62. |
| 1971 | |
|---|---|
| 008. | Agosta, William C.; Smith, Amos B., III. Photochemical reactions of simple cyclopentenones. Journal of the American Chemical Society (1971), 93 (21), 5513-20. |
| 007. | Agosta, William C.; Smith, Amos B., III. New photochemical reaction of cyclopentenones. Journal of the Chemical Society [Section] D: Chemical Communications (1971), (7), 343. |
| 1970 | |
|---|---|
| 006. | Agosta, William C.; Smith, Amos B., III. Preparation and reactions of 2,2-dimethyl-4-cyclopentene-1,3-dione. Journal of Organic Chemistry (1970), 35 (11), 3856-60. |
| 005. | Agosta, William C.; Smith, Amos B., III. 2,2-Dimethylcyclopent-4-ene-1,3-dione as a dienophile and a dipolarophile. Journal of the Chemical Society [Section] D: Chemical Communications (1970), (11), 685-6. |
| 004. | Smith, Amos B., III; Agosta, William C. Triphenylene as a singlet sensitizer. Journal of the Chemical Society [Section] D: Chemical Communications (1970), (8), 466-7. |
| 1969 | |
|---|---|
| 003. | Agosta, William C.; Smith, Amos B., III; Kende, Andrew S.; Eilerman, Robert G.; Benham, Judith. Intramolecular photorearrangement of cyclopentenones. Tetrahedron Letters (1969), (52), 4517-20. |
| 1968 | |
|---|---|
| 002. | Heine, Harold W.; Smith, Amos Brittain, III; Bower, J. David. Aziridines. XVIII. Reactions of a 1,3-diazabicyclo-[3.1.0]hex-3-ene with alkenes, alkynes, and diethyl azodicarboxylate. Journal of Organic Chemistry (1968), 33 (3), 1097-9. |
| 1963 | |
|---|---|
| 001. | Heine, H. W.; Smith, Amos B. III. Isomerization of 1,3-diphenyl-2,2-dichloroaziridine. Angew. Chem. (1963), 75 (14), 669-70. |