Great poster and research!!! Excellent mentoring by Sarah Matar.
Excited to welcome Peter Ishola to the lab! Peter is very passionate about chromatin and Polycomb repression. He joins us from Nigeria.
Sammy successfully defended her thesis on 11/19/2021 and we celebrated with the plant group and her friends and family!
This review covers comparative analysis of PRC2 structure and function in animals and plants:
We condemn the grave injustices that black people confront in this country, in particular the unbridled and deplorable police brutality and express our sorrow about the many lives this has taken, compounded by lack of equal healthcare, housing and employment that is causing more illness and death among black people during COVID19; racial profiling, mass incarcerations, wrongful convictions and many more injustices and no end in sight for 400 years.
Dr. Doris Wagner present a lecture in Biol425 superlab to modify activity of plant chromatin regulators
Wagner Lab graduate student Samantha Klasfeld introduced the CAMB/BIOL 483 class to a wide array of genome-wide sequencing technologies and then focused on the logic needed to inform quality control and analysis of these types of data sets.
Two positions are available in the Wagner lab to investigate developmental and environmental reprogramming of cell fate and function in Arabidopsis in the context of chromatin. We study reprogramming in a variety of biological contexts using a combination of approaches.
The positions are in the following areas:
How do plants tell time? Seasonal cues such as daylength determine when plants flower. Mobile plant proteins like TFL1 co-ordinate this transition. Use genetic, biochemical and imaging approaches to understand how they execute this role.
Epigenetic tailoring of phenotypes Use selective tethering, destruction, or repurposing of master chromatin factors to modulate organism form and function. Requires reverse genetic, biochemical, chemical biology and molecular approaches.
Compare the mode of Polycomb repressive complex 2 recruitment in species with small and large genomes. Use of epigenomic, computational (including machine learning), molecular and reverse genetic approaches to test the hypothesis that large genome size/ repetitive DNA content necessitate a different mode of Polycomb recruitment as the one we and others described for Arabidopsis.
The successful candidate should be about to complete or have recently completed their PhD and should have a strong publication record. We look for an applicant that is able to work both independently and in a team, and is highly productive. Proficiency in either confocal imaging, protein purifications/mass spec, genomic approaches or computational biology/modeling is desirable.
The University of Pennsylvania Biology Department has an excellent core of Plant Biology research groups, and the Wagner group is also part of the superb Penn Epigenetics Institute. Philadelphia is a vibrant and livable city, bike friendly and walkable, with great restaurants and other activities.
Those interested should submit a cover letter (1-2 pages) outlining their research interest and career goals, a current curriculum vitae, and names and contact information of three referees to firstname.lastname@example.org