Abstract: Soft, bio-integrated materials and devices exhibit the ability to collect physiological signals and offer therapeutic functions, posing a substantial impact on our understanding of biology and paving the way for precision medicine. With the assistance of advanced ultrasound technology, the innovative integration holds immense promise for sensing, modulation and actuation in deep tissues and […]

Abstract: The data science ecosystem encompasses data fairness, scalable and powerful statistical and ML/AI methods and tools, and trustworthy science by accounting uncertainty and improving interpretability.  In this talk, I will discuss the challenges and opportunities as we navigate the crossroad of statistics and AI to empower genomic health data science. Examples include leveraging the AI/ML-generated […]

Abstract: In every human cell, 6 ft of DNA and thousands of RNAs and proteins are compacted to fit inside a tiny nucleus. Yet, these molecules are not randomly arranged in the nucleus. Instead, proteins, DNAs, and RNAs are organized in specialized compartments like nuclear bodies, which are thought to play key roles in RNA […]

Abstract: Animals can easily adapt their bodies and movements to new, unstructured environments and situations. Robots cannot. While engineers construct robots from rigid, motorized mechanisms to precisely control their movements, vertebrates leverage compliant, deformable musculoskeletal systems to adaptively navigate complex environments and produce dynamically stable gaits and motions. Providing robots with an equivalent musculoskeletal system […]

Abstract: The Yokoyama Lab studies the genetics underlying neurodegeneration in diverse populations, with a particular focus on Alzheimer’s disease and frontotemporal dementia. We utilize statistical genetics to elucidate contributions to selective vulnerability for neurodegenerative disease. We also assess transcriptomic profiles in the periphery and brain to identify new biomarkers of disease. Finally, we engage in collaborations […]