The Bonini lab specializes in using the genetically tractable model organism, Drosophila, as a tool to understand the molecular basis of disease and disorder of the brain, with a particular focus on degenerative processes including ALS/FTD, TBI and aging.  We implement cutting-edge genetic, molecular and cellular approaches to develop and characterize models of these processes to study their molecular basis, with an emphasis on potential translatability to clinical improvement. Visit our research page to learn more about active projects in the lab.